Spatial Proteomics and Transcriptomics 2

• 3950 Spatial transcriptomic dissection of microenvironmental drivers of NMIBC progression Jacob Alltucker, Yiling Shen, Suhyeon Choi, Pavithra Nedumaran, Andrew Martinez, Joseph Lownik, Huihui Ye, Hideki Furuya, Dan Theodorescu, Simon Knott
• 3951 · PDF Spatial mapping of B7-H3 mediated cellular plasticity in treatment naive pancreatic cancer Assya Legrini, Tengyu Zhang, Mari-Claire McGuigan, Colin Wood, Luke McNickle, Claire Kennedy-Dietrich, Ghazal Latifi, Yoana Doncheva, Josefina Vasquez, Hannah Morgan, Pamela McCall, Michail Doukas, Joanne Edwards, Nigel Jamieson
• 3952 · PDF Spatial multi-omics dissection of follicular lymphoma by GlycoScope-IN-DEPTH reveals a galectin-8L-driven complement-enriched, immune-exhausted microenvironment Stephanie P. T. Yiu, Ankit Basak, Carolina Ortiz-Cordero, Alex K. Shalek, Laura Kiessling, Sizun Jiang
• 3953 · PDF Assessing the role of immune aggregates as potential biomarkers of immunotherapy response in appendiceal adenocarcinoma (AA) using spatial proteomics Matt Lastrapes, Eleanor A. Fallon, Brenda Melendez, Bharat B. Singh, Davis Ingram, Khalida M. Wani, Lon W. Fong, Ashish Damania, Vivian Orellana, Nadim J. Ajami, Jillian Losh, Alexander Lazar, Kanwal Pratap Singh Raghav, John P. Shen, Melissa Taggart, Jennifer A. Wargo, Beth A. Helmink, Paul A. Scheet, Michael Geoffrey White
• 3954 · PDF Identifying biomarkers of response in BRAF p.V600E mutant colorectal cancers (mCRC) Gagandeep Brar, Brooke Rhead, Unnati Jariwala, Stamatina Fragkogianni, Amit Mahipal
• 3955 · PDF Spatial characterization of tumor-immune interactions in MMR-p and MMR-d among African American colorectal cancer patients using attention-based modeling Hassan Brim, Khushi Desai, Shweta Dixi, Justin Hong, Colles Price, Jonathan H. Chen, Nicolas Fernandez, Sara Sim, Sami Farhi, Rabia Zafar, Elham Azizi, Hassan Ashktorab
• 3956 · PDF Spatial transcriptomic mapping of ER-positive breast tumors reveals immune pathway remodeling and resistance mechanisms following anti-PD-1 therapy Oliver J. De Sa, Megan Hopkins, Angel Arnaout, Arif Awan, Gregory Pond, Jane Bayani, Melanie Spears
• 3957 · PDF Spatially derived transcriptomic predictors of immune checkpoint blockade outcome in advance gastric cancer Changjin Hong, Sunho Park, Jean R. Clemenceau, Minji Kim, Inyeop Jang, Seock-Jin Chung, Sung Hak Lee, Sam C. Wang, Tae Hyun Hwang
• 3958 · PDF Spatial transcriptomic profiling of peritoneal metastases identifies multicellular programs in patient tumors undergoing pressurized intraperitoneal aerosol chemotherapy (PIPAC) Heini Maaret Natri, Arianna L. Williams-Katek, Muhammad Talha Waheed, Tiana Li, Marwan Fakih, Mingye Feng, Amit Merchea, Sue Chang, Richard L. Whelan, Danielle Deperalta, Thanh H. Dellinger, Nicholas Banovich, Mustafa Raoof
• 3959 · PDF Novel methodology to explore glioma malignant transformation with spatial multi-omics Michal Polonsky, Jonathan Fox, Sheel Shah, Noa Hadas, Richard Everson, Long Cai
• 3960 · PDF Spatially resolved transcriptomic signatures of gallbladder carcinogenesis from precursor to undifferentiated stages Yeseul Kim, Yoseob Lee, Harim Oh, You-Na Sung, Yoo Jin Lee, Yona Kim, Inho Park, Jinhyuk Bhin, Su-Jin Shin
• 3961 · PDF Identifying the molecular signature of infiltrating edge cells in glioblastoma as drivers of tumour invasion and recurrence Alyona Ivanova, Shamini Ayyadhury, Yanxia Ma, Xuehong Gui, Akshay V. Basi, Megan Yijun Wu, Trevor J. Pugh, David G. Munoz, Sungnam Cho, Tosin Oyewale, Lucas Schütz, Chibawanye I. Ene, Jared K. Burks, Sunit Das
• 3962 · PDF Same-species multiplex IF with HCR™Gold IF: Cross-clone benchmarking using Abcam's oncology-validated primaries Wudy Yang, Randy Chen, Harry Choi, Aneesh Acharya, Will Howat
• 3963 · PDF Spatially Resolved Cell-Cell Communication Reveals Intra-tumoral heterogeneity in Small Cell Lung Cancer Tingxiao Gao, Jalal Kazan, Fatema Zohora, Gregory Schwartz, Benjamin Lok
• 3964 · PDF Spatial profiling of the neuroblastoma tumor microenvironment using seqFISH Christopher Riccardi, Michal Polonsky, Michael J. Zobel, Rebekah Kennedy, Melody Khoshneviszadeh, Anya Zdanowicz, Bruce Pawel, James Amatruda, Long Cai, Shahab Asgharzadeh
• 3965 · PDF Spatialomics detection of neuroendocrine involvement in cancer tissue Scott T. Clarke, Chris Vonnegut, Leticia Montoya, Mae Voeun, Wenjun Zhou, Anna Cartier, Aleksey Rukavishnikov
• 3966 · PDF In situ spatial multiomic profiling of breast cancer tissue utilizing the CosMx Spatial Molecular Imager Megan Hopkins, Oliver De Sa, Dan Dion, Vida Talebian, Jane Bayani, Melanie Spears
• 3967 · PDF Spatial whole transcriptomic profiling of breast cancer tissue with CosMx Spatial Molecular Imager Megan Hopkins, Oliver De Sa, Dan Dion, Vida Talebian, Jane Bayani, Melanie Spears
• 3968 · PDF Spatial transcriptomic features associated with response to neoadjuvant therapy in triple-negative breast cancer Shiqing Liao, Teia Noel, Joseph Lownik, Pavithra Nedumaran, Yoona Yang, Richard Mebane, Aagam Shah, Andrew Martinez, Akil A. Merchant, Simon Knott
• 3969 Stereoseq spatial transcriptomics reveals cell-type contributions to prostate cancer metastasis Jonathan Panzer, Shannon Carskadon, Albert Levin, Sean Huang, Vikrant Kumar, Indra Adrianto, Nallasivam Palanisamy
• 3970 · PDF Genome wide testing of archived ovarian and uterine carcinosarcoma FFPE tissue using FusionPlus Hi-C to determine HRD status Amanda Bradshaw, Christopher Elms, Mia Jeffris, Jon Belton, Williams Ricketts, Alex R. Hastie, Michael Birrer
• 3971 · PDF Rapid antibody drug conjugate markers and RNA biomarkers in solid tumors using a hybrid Ultivue InSituPlex and Protease-Free RNAscope Workflow Patrick Savickas, AKASH PARVATIKAR, Jack Casey, Anushka Dikshit, AMAN TYAGI
• 3972 · PDF Comprehensive immune landscape analysis of solid tumors using a 17-Plex immunofluorescence assay in clinical trials Jaspreet Kaur, Richard Van Krieken, Xun Li, Ying Huang, Lisa Kattenhorn, Naveen Dakappagari, Margaret E. McLaughlin, Jennifer Bordeaux
• 3973 · PDF A framework for antibody validation via spatial proteo-transcriptomics using the CellScape platform Tim Schunk, Tim Mandelkow, Shida Xiong, Jonas Raedler, Rodler Severin, Philipp Nuhn, Anne Letsch, Marion van Macklenbergh, Jan Weitkamp, Jakob Kohler, Arne Christians, Oliver Braubach, Steve Lott, Micaela Mathiak, Gavin Gordon, Björn Konukiewitz, Christoph Rocken, Niclas Christian Blessin
• 3974 · PDF Decoding cancer hallmarks through single-cell whole transcriptome imaging in invasive ductal carcinoma Claire Williams, Patrick Danaher, Megan Vandenberg, Martin Shelton, Mirko Corselli, Christine Kang, John Lyssand, Joseph Beechem
• 3975 · PDF Spatially resolved multi-omics reveal metastatic ecosystem remodeling and immunomodulatory niches in HGSOC Yufeng He, Ce Luo, Yuanguang Meng, Zhe Zhang, Zexian Zeng

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