Early Detection Biomarkers 1

• 1091 · PDF Noninvasive diagnosis of solid pulmonary nodules using peripheral blood ctDNA: Development of a multimodality platform Gunangyu Bai, Luyan Shen, Shaohua Ma, Shugeng Gao
• 1092 · PDF Multi-analyte blood-based screening early detection of HPV-associated oropharyngeal and anal cancer within the PLCO cohort Krystle A. Kuhs, Hilary Robbins, Li Chen, Xiaoshuang Feng, Yana Al-Inaya, Gjystina Lumaj, Samuli Eldorfs, Qin Wang, Tim Waterboer, Dipon Das, Daniel Faden
• 1093 · PDF Validation of a blood test for multi-cancer risk stratification in a lung cancer screening cohort Ehsan Irajizad, Johannes Fahrmann, Hamid Rudsari, Jody V. Vykoukal, Iakovos Toumazis, Sara Khoramisarvestani, Sara Ansari, Jane Yang, Nicole M. Kettner, Jennifer B. Dennison, Edwin Justin Ostrin, Samir M. Hanash
• 1094 · PDF Circulating tumor DNA (ctDNA) for molecular residual disease (MRD) detection and recurrence monitoring in hepatocellular carcinoma (HCC); COSMOS-HCC01 Masashi Kudo, Mitsuhito Sasaki, Shinji Itoh, Teiichi Sugiura, Tsuyoshi Kobayashi, Keishi Sugimachi, Shinichi Nakanuma, Yuta Abe, Hisashi Kosaka, Nobuhiro Nakamoto, Naoto Yamamoto, Makoto Ueno, Takuji Okusaka, Atsushi Takebe, Minoru Esaki, Kazuyoshi Ohkawa, Hisateru Komatsu, Yu Takahashi, Masatake Tanaka, Takeshi Aramaki, Tomokazu Kawaoka, Rie Sugimoto, Taro Yamashita, Takashi Yamaguchi, Masatoshi Kudo, Masato Ozaka, Chiemi Notake, Hiroshi Uchigata, Masafumi Ikeda, Naoto Gotohda, Yoshiaki Nakamura
• 1095 · PDF ARID1A protein expression enhances risk stratification in colorectal polyp surveillance Aula Ammar, Amna Matly, Kimiya Kabiri Arani, Scott Murray, Mayuri Hendricks, Alexander Winton, Natalie Fisher, Gerard Lynch, Mark Johnstone, Colin Steele, Noori Maka, Jennifer Hay, Philip Dunne, Stephen McSorley, Joanne Edwards
• 1096 · PDF OncoSeek 2.0: An advanced multi-cancer blood test enhancing early detection and aiding cancer diagnosis Mao Mao, Yong Shen, Shiyong Li, Wei Wu, Yinyin Chang, PingPing Xing, Chenyu Ding, Dandan Zhu, Qingxia Xu, Wei Cui
• 1097 · PDF Performance of a blood-based screening test for the early detection of advanced precancerous lesions Prashanthi Natarajan, Preethi Srinivasan, Hsiao-Yun Huang, Alan Selewa, Rebecca Panitch, Caitlin Guccione, Fatemeh Almodaresi, Jayashree Joshi, Su Maw, Misagh Kordi, Yunshu Song, Yu Lin, Osama Khan, Breeana L. Mitchell, Adham Jurdi, Minetta C. Liu, Johannes G. Reiter, Trupti Kawli, Matthew Rabinowitz, Alexey Aleshin
• 1098 · PDF Discrete precancer subtypes and biomarkers of cancer progression identified with spatiotemporal analysis of CDH1-driven diffuse gastric cancer Jeremy L. Davis, Amber Famiglietti, Yunhe Liu, Rachael Belcher, Sun A Kim, Baktiar O. Karim, Donna Butcher, Linghua Wang
• 1099 · PDF The RNA editing enzyme ADAR1 is involved in carcinogenesis associated with intraductal papillary mucinous neoplasm Masashi Kayano, Kunitoshi Shigeyasu, Kazuya Moriwake, Toshiaki Takahashi, Eiki Miyake, Yuhei Kondo, Yuya Sakurai, Shunsuke Nakamura, Masafumi Takahashi, Kaori Nitta, Kazuya Yasui, Tomokazu Fuji, Kosei Takagi, Hiroshi Tazawa, Toshiyoshi Fujiwara
• 1100 · PDF Epigenetic profiling identifies markers of aggressive cancer subtype using a targeted methylation-based multi-cancer early detection (MCED) blood test Kezhong Chen, Jian Huang, Dahong Zhang, Shu Wang, Hongxu Liu, Wenzhao Zhong, Xiangnan Li, Qiang Zhang, Zhigao Li, Jiaqi Liu, Ziqing Tian, Fei Zhou, Gongsheng Jin, Xudong Xiang, Zhigang Li, Hui Xie, Ya Wei, Guochun Zhang, Guolin Ye, Ming Cai, Junfeng Wang, Yan Zhang, Chao Cheng, Hefei Li, Desong Yang, Jianhong Lian, Sheng Huang, Tao Xu, Zengjun Wang, Xi Guo, Zhuowei Liu, Minfeng Chen, Yang Wang, Yue An, Yanzhan Yang, Min Li, Jing Liu, Baoliang Zhu, Yonghui Li, Xiaohui Wu, Fan Yang, Jun Wang
• 1101 · PDF A novel method for tumor fraction estimation using methylation sequencing data Daokun Sun, Yu Sun, Alex Robertson, Lee A. Albacker, Chang Xu
• 1102 · PDF Uncovering early transcriptional alterations in lung cancer: Preliminary insights from the Boston Lung Trans-omics (BOLT) Initiative Yu Chen Zhao, Li Su, Lorelei A. Mucci, Timothy R. Rebbeck, Yi Li, David C. Christiani
• 1103 · PDF The genomic landscape of melanoma-prone skin Katie Lee, Yung-Ching Kao, Darren Smit, Marietta K. Saldias Montivero, Joshua Jay Levy, Brock C. Christensen, Quan Nguyen, H. Peter Soyer, Mitchell S. Stark
• 1104 · PDF Detection of bladder cancer via urinary DNA mutation and methylation using modified qPCR Di Jin, Roy Tan, Ruiyun Zhang, Haige Chen
• 1105 · PDF Nestin expression is prevalent but highly variable in human cancer: A tissue microarray study involving 5,917 cancers from 107 tumor entities Clara von Bargen, Muriel Torzewski, Fiete Gehrisch, Anne Menz, Florian Lutz, Viktoria Chirico, Florian Viehweger, David Dum, Ria Schlichter, Andrea Hinsch, Christoph Fraune, Chrisitan Bernreuther, Seyma Büyücek, Martina Kluth, Claudia Hube-Magg, Georgia Makrypidi-Fraune, Nina Schraps, Katharina Möller, Andreas M Luebke, Patrick Lekok, Guido Sauter, Maximilian Lennartz, Till Clauditz, Andreas H Marx, Ronald Simon, Eike Burandt, Natalia Gorbokon, Maria Chrisitna Tsourlakis, Sarah Minner, Till Krech, Morton Freytag, Viktor Reiswich, Stefan Steurer
• 1106 · PDF Rapid identification of comprehensive multi-omic protein and RNA biomarkers on a single FFPE tissue section using a novel integrated nCounter® workflow Lakshmi Chandramohan, Kirsteen Maclean, Quratul Ain, Brigitte Lovell, Lisa Duncan, Sergio Hernandez, Christina Bailey, Michael Bailey, Patrick Danaher, Wei Yang, Shanshen He, Joseph M. Beechem
• 1107 · PDF Development and performance of a multiomics lung cancer screening blood test Ofer Shapira, Alexander F. Lovejoy, Álvaro González, Urvee Desai, Thomas Royce, Gurnit Atwal, Ian Bast, Eric Beraut, Alexandra Buckley, Austin Cauwels, Peter Combs, Nicholas Eisele, G Parker Flowers, Lourdes Gomez, Rebecca Gupte, Johnnie Hahm, Teng-Kuei Hsu, Saiful Islam, Poorval Joshi, Amanda Kahn-Kirby, Phuong Thuy Menchavez, Erene Mina, Jinesh Niroula, Cameron Pospisil, Sodany Son, Rashmi Sriram, Peter Ulz, Russell Williams, Rui Yang, Wilson Zhang, Marian Navratil, C Jimmy Lin, Tanya Moreno, Richard Bourgon
• 1108 · PDF Performance of an optimized methylation-protein multi-cancer early detection (MCED) test classifier Vladimir G. Gainullin, Melissa Gray, Madhav Kumar, Stephen Luebker, Amy Lehman, Darl D. Flake, Avinash Shanmugam, Kevin Cortes, Emily Chang, Philip J. Uren, Amin Mazloom, Jorge Garces, Gerard A. Silvestri, David W. Chesla, Robert W. Given, Tomasz M. Beer, Frank Diehl
• 1109 · PDF The complementary contributions of methylation and protein biomarker classes in a multi-cancer early detection (MCED) test Vladimir G. Gainullin, Melissa Gray, Madhav Kumar, Stephen Luebker, Avinash Shanmugam, Kevin Cortes, Emily Chang, Philip J. Uren, Amin Mazloom, Jorge Garces, Tomasz M. Beer, Frank Diehl
• 1110 · PDF Promote biomarker identification for early detection of head and neck cancers through AHEAD and EDRN programs under the leadership and collaboration between NIDCR and NCI Zhong Chen, Wendy Wang, Guillermo Marquez, Jason Wan, Sudhir Srivastava
• 1111 · PDF Promoting awareness and enhancing access to low-dose computed tomography screening for early detection of lung cancer in underrepresented minority communities in Northern Illinois Subaranjana Saravanaguru Vasanthi, Georgia Kapetaneas, Rose Bahari, Shylendra B Sreenivasappa, Nameer Mardini, Sandra Martell, Joseph Ross, Yamilé Molina, Neelu Puri
• 1112 · PDF Circulating early myeloid-derived suppressor cells as indicators of tumor-driven myelopoiesis and disease progression in lung cancer Anna Zanichelli, Orazio Fortunato, Mara Lecchi, Paolo Verderio, Luigi Rolli, Ugo Pastorino, Gabriella Sozzi, Claudia Chiodoni, Sabina Sangaletti
• 1113 Clinical validation of a targeted multi-cancer early detection (MCED) test using cfDNA mutation and integrated genomic signatures analysis Chee-Onn Leong, Boon Shing Tan, Hiu Ching Toh, Ee Mun Loo, Anand Mohan, Teryna Thu, Zhi Win Ng, Xin Yi Chew, Chin King Looi, Felicia Fei Lei Chung, Chun Wai Mai
• 1114 · PDF Informatics-Driven Integration of OpenMRS and iBreastCheck to Strengthen Community-Based Cancer Screening in Ethiopia Tsedey Michele Tsegaye, Mukesh kumar Patel, Tulay Soylu
• 1115 · PDF Expression of annexin A4 in cancer: A tissue microarray study involving 6,058 cancers from 105 tumor entities Cosima Völkel, Nayma Malas, Fiete Gehrisch, Nina Schraps, Anne Menz, Florian Lutz, Viktoria Chirico, Florian Viehweger, David Dum, Ria Schlichter, Andrea Hinsch, Christoph Fraune, Christian Bernreuther, Seyma Büyücek, Martina Kluth, Claudia Hube-Magg, Georgia Makrypidi-Fraune, Katharina Möller, Andreas M. Luebke, Patrick Lebok, Guido Sauter, Maximilian Lennartz, Till S. Clauditz, Andreas H. Marx, Ronald Simon, Eike Burandt, Natalia Gorbokon, Maria C. Tsourlakis, Sarah Minner, Till Krech, Morton Freytag, Viktor Reiswich, Stefan Steurer
• 1116 · PDF A scalable multimodal framework for unbiased risk biomarker discovery across multiple cancer types Constantin Petrescu, Lisa Schmunk, Jack Monahan, Abbas Salami, Thomas M. Stubbs
• LB371 · PDF Prospective investigation of the blood metabolome to identify risk biomarkers for biliary tract cancer Valerie Gunchick, Wei Zheng, Chris Haiman, Caroline Um, Roger Milne, Rachel Solomon, Yu Chen, Andrew Chan, Qiuyin Cai, Xiao-Ou Shu, on behalf of the BTC Metabolomic Consortium

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