Liquid Biopsies: Circulating Nucleic Acids 4

• 5306 Transcriptomic analysis of small extracellular vesicles in metastatic breast cancer Emmanuel Acheampong, Tumisang Ntereke, Katie Dixon, Karen Page, Shradha Bhagani, Naila Abid, Marc Wadsley, Rebecca Allsopp, Charles Coombes, Jacqui Shaw
• 5307 · PDF Analytical performance of an ultrasensitive whole genome sequencing assay for molecular residual disease detection Andrew Georgiadis, Christopher Greco, Cynthia Maddox, Paul McGregor, Cesar Nalvarte, Kaitlin Victor, Amanda Harvey, Shelby Bain, Robert Summersgill, Ana Perez-Lebron, Liam Cox, Stephen Higgings, David Riley, Samuel Angiuoli, Marcia Eisenberg, Brian Caveney, Eric Severson, Taylor J. Jenson, Shakti Ramkissoon, Mark Sausen
• 5308 · PDF Monitoring treatment response in metastatic breast cancer patients using an mDETECT assay Keira Frosst, Brooke E. Wilson, Katarzyna J. Jerzak, Christopher R. Mueller
• 5309 · PDF Baseline ctDNA profiling identifies molecular predictors of resistance to second-generation ALK inhibitors in EML4-ALK-positive NSCLC Emma Roger Sønderbek, Maiken Parm Ulhøi, Peter Meldgaard, Boe Sandahl Sorensen
• 5310 · PDF Dynamic changes in ctDNA methylation predict early response to immunotherapy in advanced esophageal cancer Hui Zhang#, Yu Lang#, Yaping Dong#, Wei Li#, Jialin Lin, Lu Yang, Jiapeng Kang, Wenqiang Yu*, Changshun Yang*, Jingxun Wu*, Qiyuan Li*, Feng Ye*, Weiwei Tang*
• 5311 · PDF Tracking prostate cancer progression by deep whole genome sequencing of primary tumors and longitudinal circulating tumor DNAs Samira Rahimirad, Eleonora Scarlata, Lucie Hamel, Seta Derderian, Ginette McKercher, Fadi Brimo, Fred Saad, Armen Aprikian, Simone Chevalier
• 5312 · PDF Digital PCR-based plasma DNA methylationassayfor noninvasive molecular subtyping of small cell lung cancer: A prospective feasibility study Jin-Soo Kim, Mi Young Kim, Jeemin Yim, Yun Young Lee, Joon An, Jinil Han, Ji Eun Kim, Youngho Moon
• 5313 · PDF Fragmentomic analysis of cfDNA WGS at regulatory regions generates gene-level expression-like traits for subtype analysis in breast cancer Jonathan H. Shepherd, Jeff Burdine, Yoichiro Shibata, Gregory M. Mayhew, Gabe Milburn, Michael V. Milburn, Matthew LaBella, Shalee Killpack, Kirk L. Pappan, James M. Davison, Kirk Beebe
• 5314 · PDF Combining gene expression and mutation profiling in a single cfDNA assay through the addition of a custom hybrid capture panel targeting gene regulatory regions to a commercial CGP panel Gregory M. Mayhew, Jonathan H. Shepherd, Yoichiro Shibata, Jeff Burdine, Gabriel V. Milburn, Kirk L. Pappan, Nripesh Prasad, Michael V. Milburn, James M. Davison, Kirk Beebe
• 5315 · PDF Analytical precision and cross-platform replicability of cfDNA-based genome-wide multi-feature classifiers for early cancer detection Vishruth Girish, Alice C. Eastman, Adrianna L. Bartolomucci, Akshaya V. Annapragada, Hope Orjuela, Carter Norton, Daniel H. Du, Sarah Short, Christopher M. Cherry, James R. White, Shashikant Koul, Vilmos Adleff, Zachariah H. Foda, Jillian Phallen, Victor E. Velculescu, Robert B. Scharpf
• 5316 · PDF Analytical validation of SPIRAL: An integrated genomic and epigenomic liquid biopsy assay Lei Wang, Peiru Liu, Chaoran Zheng, Shanshan Yu, Yalan Jin, Fujun Qiu, Bo Yang, Yuan Sun, Xiaotian Wang, Shuailai Wu, Zhihong Zhang
• 5317 · PDF Evaluation of circulating tumor DNA as a biomarker for early relapse detection and molecular profiling in patients with high-risk neuroblastoma Natalia Wojciechowska, David Farbo, Tiffany Duque, Angela Brentlinger, Chelsee Greer, Anish Ray
• 5318 · PDF A low-cost, ultra-fast, low-input amplicon NGS workflow for rapid cancer profiling Fang Liu, Kemin Zhou, Pan Du, Binggang Xiang
• 5319 · PDF Circulating tumor DNA (ctDNA)-based profiling of acquired resistance to the fibroblast growth factor receptor (FGFR)2/3 inhibitor lavengratinib(ABSK061) in patient(pt)s with advanced solid tumors Yue Wang, Chunyu Zhou, Liyun Zhao, Chaoze Cheng, Zhixuan Zhu, Zishuo Wang, Peng Zhang, Jing Zhang, Hua Zou, Jing Ji, Hongping Yu, Ji Zhu, Yan Zhao, Dewei Li, Yongsheng Li, Wei Li, Yanru Qin, Shujun Yang, Nannan Zhang
• 5320 · PDF Leveraging enhanced conversion efficiency of the KAPA EvoPrep Boost workflow for urine ctDNA detection Angela Apessos, Maria Shin, Yanpeng Xi, Stephanie J. Yaung, Indira Wu
• 5321 · PDF Comprehensive profiling of urine microRNAs in prostate cancer patients Matias A. Bustos, Yoko Koh, Jaime Moon, Dai Takamatsu, SooMin Kim, Gianna Jimenez, David L. Krasne, Timothy G. Wilson, Dave S. B. Hoon
• 5322 · PDF Non-invasive tracking of clonal evolution and treatment response through liquid biopsies Farhia Kabeer, Matteo Lepur, Branden Lynch, Emilia Hurtado, Janine Senz, Ding Ma, Vinci Au, Caroline Baril, Gavin Ha, Samuel Aparicio, Jessica N. McAlpine, Alexandre Bouchard-Côté, David G. Huntsman, Yvette Drew, Andrew Roth
• 5323 · PDF Circulating tumor DNA dynamics predict the response to neoadjuvant chemotherapy but not long-term outcomes in PIK3CA -mutated breast cancer Ayaka Sato, Takayuki Ueno, Shunji Takahashi, Yoshinori Murakami, Masahiko Tanabe
• 5324 · PDF Circulating tumor DNA detects minimal residual disease and predicts outcomes in esophageal cancer after esophagectomy Qingjiang Hu, Eiji Oki, Yasue Kimura, Hajime Otsu, Yusuke Yonemura, Koshi Mimori
• 5325 · PDF Cell-free DNA fragmentomes for treatment response monitoring in patients with metastatic colorectal cancer: The Dolphin study Denise E. van Steijn, Lorenzo Rinaldi, Adria Closa, Erica Peters, Alissa Konicki, Mariska Bierkens, Haoyue Wang, Marjolein Greuter, Birgit Lissenberg-Witte, Veerle Coupé, Amoolya Singh, Timothy McDaniel, Meike de Wit, Anna Houben, Daan van den Broek, Miriam Koopman, Gerrit Meijer, Max Lahaye, Manon Braat, Victor Velculescu, Jeanine Roodhart, Nicholas Dracopoli, Frederieke van der Baan, Geraldine Vink, Niels Kok, Remond Fijneman
• 5326 · PDF High throughput genomic profiling of tissue and liquid biopsy samples reveals targetable mutations in NSCLC patients from the Indian population Amit Kumar, Puja Sinha, Rama Chandran, Shobit Gupta, Giulliana Tessarin
• 5327 · PDF Utilization of urinary cell-free DNA as an informative biomaterial for comprehensive genomic profiling Robert Summersgill, Jesse Fox, Patrick Horn, LaRonda White, Vito Caropreso, Amy Meltzer, Ana Perez-Lebron, Kenneth Valkenburg, Eric Severson, Taylor J. Jenson, Shakti Ramkissoon, Brian Caveney, Marcia Eisenberg
• 5328 · PDF Analytical performance of magnetic bead-based cfDNA extraction with a low input targeted DNA enrichment Mayer Saidian, Yingmin Wang, Heng Wang, Yun Bao, Jason Saenz, Carlos Hernandez, Cameron Van Dieren, Daniel Cedeno, Nafiseh Jafari
• 5329 · PDF Unlocking transrenal DNA: New methods for stabilizing and isolating small cfDNA in urine Daniela Mancarella-Langer, Franziska Kaiser, Daniel Groelz, Moritz Rath, Nguyen Van Nhi Le, Eric Provencher, Michelle Walther

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