Insights into Genomic Instability

• 4681 · PDF Probing the RecQL4 homolog Hrq1: A genetic suppressor screen identifies critical functional features Robert H. Simmons, Matthew Bochman
• 4682 · PDF Metabolic enzymes as protective modulator of BRCA2 haploinsufficiency and genome instability Xiao Zi Huang, Tuan Zea Tan, C. Pawan K. Patro, Li Ren Kong, Ashok R. Venkitaraman
• 4683 · PDF Loss of nuclear integrity at persistent DNA bridges ties PARP inhibitors to cGAS/STING signaling Ece Koçak, Kerry A. Larkin, Nicholas R. Ader, Yiduo Hu, Kevin Li, C. Patrick Lusk, Anna Dominika Staniszewska, Mark R. Albertella, Megan C. King
• 4684 · PDF A RHNO1-ATR/Chk1 positive feedback loop sustains the cellular DNA replication stress response Niphat Jirapongwattana, Carley M. Conover, Catalina Trujillo Jaramillo, Adam R. Karpf
• 4685 Intestinal inflammation triggers POLE P286 R -driven ultramutated colorectal cancer Md Kawsar Mustofa, He Zhang, Diego H. Castrillon, Hasan Zaki
• 4686 Lymphatic niches shield stem cells from malignant fate Ananya Goyal, Madison Conte, Shiri Gur-Cohen
• 4687 · PDF The BRCT domain is a modular platform for signal transduction in the DNA damage response Nicholas Woods, Thales Nepomuceno, Rebekah Baskin, Rafael Mesquita, Volha Golubeva, Xueli Li, Nicholas Palermo, John M. Koomen, Alvaro N. Monteiro
• 4688 · PDF The nuclease EXO1 promotes genomic instability by degrading nascent DNA in BRCA-proficient cells Alexandra Nusawardhana, Claudia M. Nicolae, George-Lucian Moldovan
• 4689 · PDF Dynamic and defective repair of extrachromosomal DNA drives genome instability in cancer Shu Zhang, Yanbo Wang, Thomas B. K. Watkins, Xiaowei Yan, Aditi Gnanasekar, Jun Tang, Ivy T. Wong, Howard Y. Chang, Paul S. Mischel
• 4691 · PDF Assessing prognostic and therapeutic associations across EMAST, MSI, and MSS among African Americans colorectal cancer subtypes Hassan Brim, Mudasir Rashid, Ahmed Imran, Somtochukwu Abazu, yumna siddiqui, Shweta Dixit, Anas Brim, Wardah Bajwa, Mrinalini Deverapal, Rumaisa Rashid, Aurmin Amirmokri, Chibuzor Nwachukwu, Neda Dezfuli, Rabia Zafar, Gholamreza Oskrochi, Zaki Sherif, Adeyinka O Laiyemo, John Carethers, Babak Shokrani, Hassan Ashktorab
• 4692 · PDF Environmental toxin-induced m6A RNA modification promotes R-loop accumulation and chromosomal instability Rebekah Gridley, Palakshi Bandapalli, Sharmila Govindaraj, Siddhant Meshram, Suvo Chatterjee, Gurdeep Singh, Arunkumar Ganesan
• 4693 · PDF The cancer testis antigen, HORMAD1, promotes genomic stability in lung adenocarcinoma Ronnesha Johnson, Angelique Whitehurst, Anthony J. Davis, Luis Reza Herrera
• 4694 · PDF Oxidative base damage to telomeres sensitizes cancer cells to ATR inhibition Alex Garbouchian, Natalia Cestari Moreno, Aninda Dey, Patricia Lynn Opresko, Ryan Barnes
• 4695 · PDF Distinct genomic remodeling in Li Fraumeni Syndrome breast cancer Nabamita Boruah, Renyta Moses, Ryan Hausler, Heena Desai, Maliha Tayab, Ahn Le, Gregory Kelly, Anupama Nayak, Kara Maxwell
• 4696 · PDF Oncogenic transcriptional rewiring in micronuclei Duaa Hassan Al-Rawi, Danguole Norkunaite, Kaden Southard, Mercedes Duran, Xuelan Chen, Andrew William McPherson, Scott W. Lowe, Sohrab Shah, Samuel F. Bakhoum
• 4698 · PDF Quantifying ongoing chromosomal instability using single-cell whole-genome sequencing Barbara Hernando, Blas Chaves-Urbano, Maria Escobar-Rey, Alice Cadiz, Angel Fernandez-Sanroman, Marina Torres, Sara Barrambana, Carmen G. Lechuga, Carmen Guerra, Mariano Barbacid, Maria Garcia-Perez, Patricia G. Santamaria, Geoff Macintyre
• 4699 · PDF CK2alpha is a novel phosphoinositide effector of PIPKIIalpha and PIPKIIbeta in DNA damage repair Gavril Limet Ibaan, Suyong Choi

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