Metabolic Features of Thoracic and Urologic Cancers

• 4728 Loss of LKB1 promotes lactate utiliaztion in KRAS -mutant lung adenocarcinoma Yu Qian, David Molkentine, Yifan Kong, Amirali Karimi, Qian Huang, Chendong Yang, Ralph J. DeBerardinis, John V. Heymach
• 4729 LINE-1 retrotransposition drives lipid metabolic reprogramming and immune suppression in lung squamous cell carcinoma via cPLA2/5-LOX axis Rui Zhang, Wenjing Tian, Pengpeng Liu, Jinpu Yu
• 4730 · PDF Construction of a prognostic model for small-cell lung cancer based on lipid metabolism related proteins Haohua Zhu, Aijuan Yu, Huiyang Shi, Jingyu Lu, Kai Zhu, Miaohan Wang, Yi Liu, Naizhong Zheng, Xingsheng Hu
• 4731 · PDF Cysteine oxidation is required for brain metastasis in lung cancer Maolin Ge
• 4732 Anaplastic lymphoma kinase harnesses the SLC4A7 bicarbonate transporter to intensify de novo nucleotide synthesis in neuroblastoma and lung cancer. Ruth Palmer, Wei-Yun Lai, Tzu-Po Chuang, Joel Johansson, Emre Can Tuysuz, Dan E. Lind, Alexander Schmidt, Michael N. Hall, Bengt Hallberg
• 4734 · PDF Metabolomic profiling among non-small cell lung cancer and non-cancer populations: A case-control study Yoo-Min Koh, Jae Jeong Yang, Mi-Jeong Yoo, Qiuyin Cai, Feifei Xiao, Hiren Mehta, Lizi Wu, Hyung-Suk Yoon
• 4735 Designing a novel 3D co-culture model incorporating patient T-cells to study lipid metabolism as a metabolic vulnerability in KRAS driven non-small cell lung cancer Saoirse Flanagan, Robyn Stanley, Sze Ying Tan, Beatrice Malacrida, Noémie Petit, David O’Reilly, Jarushka Naidoo, Shane Browne, Paul Murray, Catríona M. Dowling
• 4736 · PDF Trace metal signatures in non-small cell lung cancer: A pilot study of patients attended at Mount Sinai Hospital in New York City Diddier Prada, Manish Arora, Julio landero, Jamshid Abdul Ghafar, Rachel Brody, Oscar Arrieta, Fred R. Hirsch
• 4737 · PDF Utilizing patient-derived organoid tumor models to combat chemo-immunotherapy resistance in NSCLC Manojavan Nagarajan, Chunjing Wu, Dao M. Nguyen, Estelamari Rodriguez, Emily Kim, Diane Lim, George Theodore, Irving Vidaurre, Wei Sha, Adeline Murphy, Jose Gomez, Durga Prasad Gannamedi Hinder, David Lombard, Lynn G. Feun, Niramol Savaraj, Medhi Wangpaichitr
• 4738 · PDF Pharmacological activation of PI3Kalpha triggers cancer cell death under metabolic stress Benoit Bilanges, Ralitsa Madsen, Daniele Morelli, Thomas Jones, Wayne Pearce, Etienne Leveille, Mustafa Kocak, Eden Bramson, Mark Bekala, Roger Williams, Nicholas McGranahan, Markus Muschen, William R. Sellers, Henning Walczak, Bart Vanhaesebroeck
• 4739 · PDF Targeting PGK1 enhances enzalutamide efficacy in resistant prostate cancer Min Zhang, Ruixin Wang, Xiaoqi Liu
• 4740 · PDF Exploiting ketone body metabolism as a therapeutic vulnerability in prostate cancer Pablo Sanchis, Agustina Ayelen Sabater, Jiabin Dong, Peter Shepherd, Nicolás Anselmino, Paul G. Corn, Elba Vazquez, Christopher J. Logothetis, Daniel Frigo, Geraldine Gueron, Estefania Labanca
• 4741 · PDF Loss of SIRT3 promotes metabolic and epigenetic dysregulation in aggressive prostate cancer Xiaochen Yu, Alphonse Nicholas Dimeck, Eriko Katsuta, Spencer Rosario, Mark Long, Song Liu, Kent Nastiuk, Hai Wang, Subhamoy Dasgupta
• 4742 · PDF Investigating the crosstalk between metabolic reprogramming and epigenetic modifications in bone metastatic prostate cancer Madison Aust, Abbas Jawadwala, Ephraim Jeremiah Gardner, Surendra Gulla, Tej K. Sharma, Remi M. Adelaiye-Ogala
• 4743 · PDF Dual inhibition of PIKfyve and FASN reveals therapeutic potential in neuroendocrine prostate cancer Yang Zheng, Caleb Cheng, Yizhi Cao, Gabriel Cruz, Yuping Zhang, Radha Paturu, Somnath Mahapatra, Jing Hu, Rahul Mannan, Huseyin Karaburk, Rupam Bhattacharyya, Yitong Yin, Xuhong Cao, Hui Xue, Chungen Li, Zhen Wang, Stephanie Miner, Ulka N. Vaishampayan, Vaibhav Sahai, Lois S. Weisman, Ke Ding, Costas Andreas Lyssiotis, Yuzhuo Wang, Yuanyuan Qiao, Arul M. Chinnaiyan
• 4744 · PDF Metabolomic profiling of fresh and formalin-fixed paraffin-embedded samples reveals metabolome alterations in penile cancer Andres Enrique Hernandez-Gonzalez, Maria Sanchez-Vazquez, Luis Torres-Peña, Keren Valentin-Lopez, Carlos A. Rivera-López, Brandon Torres-Rivera, Maria Marcos-Martinez, Antonio Puras-Baez, Nataliya Chorna, Magaly Martinez-Ferrer
• 4745 · PDF Tumor-intrinsic Warburg effect as the driver and therapeutic target for cancer-associated cachexia in mouse models Shaozi Fu, Vincent Pham, Victoria Sanchez, Yaxing Nie, Kasie Liu, Chenhui He, Yu Luan, Lingtao Jin, Gang Huang
• 4746 Downregulation of PDLIM2 promotes tumor growth through regulation of oncometabolites and HIF-1alpha pathway Tsung-Hsien Chuang, Jing-Xing Yang, Yu-Chen Chuang, Jen-Chih Tseng, Yi-Ling Liu, Chao-Yang Lai
• 4747 Chronic E-cigarette aerosol exposure induces metabolic, translational, and immune reprogramming in mice: A serum proteomics analysis Rizwana Begum, Ganesan Muthusamy, Shreya Pokharel, Biplov Sapkota, Poorna Sai Vaddi, Shang SU, Abhishek Pandit, Naveen Chintala Ramulu, Joseph Francis

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