Metabolic Alterations in Colorectal and Gastrointestinal Cancers

• 4703 · PDF Sex-specific metabolic features in pre-cancerous polyps identified in Puerto Rican stool samples: A pilot study Melissa Gabriela Soto-Santiago, Gabriel Borges Velez, Leslie A. Casiano Agosto, Luis R. Llanos, Ibis R. Vera-Urbina, Josue Perez-Santiago, Maria Gonzalez-Pons
• 4704 Disruption in cholesterol homeostasis by free fatty acid promote colon cancer by modulating CCL20 Janani Muralidharan, Ankit Bhatt, Jaliya M. Mims, Gene Hughes, Paige Marcelline, Sejong Bae, Shailesh Singh, Hina Mir
• 4705 · PDF A clearer picture of cachexia: Leveraging body composition imaging in C26 tumored mice Cheryl Davis, Liz Bailey, Mollie McArthur, Melissa Tran, Ben Hoerner, Victoria Caruso, Helen Ketteringham, Corrine Silvio, Shannan Paul, Delaney McCormick, Jocelyn Saurbaugh, Chris Holding, Aliccia Koznecki, Dawn Lusk, Shorena Nadaraia-Hoke, Kathleen Hutchinson
• 4706 Mechanoplasmonics: Integrating nanoplasmonic materials and stiffness tunable hydrogels for real-time, label-free cellular analysis Cason M. Hancock, Harlie Rios, Alexander McGhee, Swarna Ganesh
• 4707 · PDF Repurposing statins activates compensatory glutathione metabolism as synergistic vulnerability in colorectal cancer Jieqing FENG, Jianming LI, Hong YAN, Zongwei CAI
• 4708 · PDF Metabolomics signatures with multidrug-resistant colorectal cancer cells Christopher Farrell
• 4709 · PDF Metabolic reprogramming through SREBP2-driven cholesterol synthesis in CAFs of CMS4 colorectal cancer Iguru Omori, hiroaki kasashima, Yukina Kusunoki, Nobuhiro Naito, Zizhou Wang, Yuki Seki, Kenji Kuroda, Yuichiro Miki, Mami Yoshii, Tatsuro Tamura, Masatsune Shibutani, Takahiro Toyokawa, Masakazu Yashiro, Yu Muta, Yuki Nakanishi, Kiyoshi Maeda
• 4710 Comprehensive metabolomic profiling of FFPE human tissues reveals key metabolic reprogramming in colorectal cancer and associated pathways Tom Cohen, Ashima Mehta, Adam Richardson, Monil Gandhi, Douglas Guzior, Kevin Cho, Ethan Stancliffe, Gary Patti
• 4711 · PDF Investigating synergistic impact of diet-induced hyperinsulinemia and mutant Kras on colorectal cancer metastasis Anindita Mahanty, Cara Wallingford, Alexa Magstadt, Revan Hammontree, Jennifer Davis
• 4712 Targeting NRF2-regulated polyamine and glutathione metabolism enhances chemotherapy efficacy in colorectal cancer based on KRAS status Jiamin Li, Jieqing Feng, Fuyue Wang, Yingjie Zhang, Hong Yan, Zongwei Cai
• 4713 Targeting glycogen metabolism in cancer-associated fibroblasts alleviates immunosuppression and inhibits colorectal cancer malignancy Xudong Zhu, Yuning Zhou, Haoxiang Zhang, Yinping Jiang, Jinpeng Liu, Chi Wang, B. Mark Evers, Qingding Wang
• 4714 Tumor-associated macrophage creatine metabolic reprogramming enhances hnRNPA1 phase separation and promotes colorectal cancer stemness and recurrence Zhengran Zhou, Xuanhui Liu, Yifan Zheng, Zhengyu Wei, Zerong Cai, Yufeng Chen, Peishan Hu, Xiaojian Wu
• 4715 · PDF Detection of mitochondria-targeting anticancer agents in tumor organoids Yoonseok Kam, Lisa Winer, Natalia Romero
• 4716 · PDF Disruption of mitochondrial dynamics alters DNA repair capacity in colon cancer Marion D. Creech, Erin M. Wolf Horrell, Tianyan Gao
• 4717 TBK1/IKKbeta-mediated CAD phosphorylation links pyrimidine synthesis blockade and chemosensitization to innate immune activation Taolin Xie, Chi Liang, Hansong Xia, Anjie Lu, Chao Qin, Xinchi Xie, Wayne Yeh, Pinghui Feng
• 4718 Redox reprogramming protects colon cancer cells from disulfidptosis under glucose deprivation Elimelech Nesher, Subha Ranjan Das, Igor Koman
• 4719 · PDF Dissecting metabolism-driven transcriptional reprogramming in human colon and liver cancer cells Subhamoy Datta, Emilia Kotinurmi, Konsta Karttunen, Biswajyoti Sahu, Paivi Pihlajamaa
• 4720 · PDF Glutamine transporter ASCT2 as a therapeutic target in HPV positive organoid models of HNSCC Shu-Yun Cheng, Ella Jackert, Liyang Tang, Daniel Kwon, Niels Kokot, Uttam Sinha, Yang Chai, Albert Y. Han
• 4721 · PDF Cross‑species multi‑omics mapping of APC/KRAS‑driven metabolic networks Mahima Bharti, Swagata Maity, Marcos Calderon, Peng Zhang, Augustine Takyi, Marco Marchetti, Paul Stewart, Bruce A. Edgar
• 4722 · PDF Genetic background shapes mitochondrial metabolic adaptations underlying thyroid cancer progression Vincenzo Davide Pantina, Chiara Modica, Francesco Verona, Giulia Bozzari, Roberta Drago, Caterina D'accardo, Gaetana Porcelli, Sebastiano Di Bella, Rosario Brancato, Pierre Sonveaux, Matilde Todaro, Giorgio Stassi
• 4723 · PDF Dysregulated lipid metabolism accompanies chromosomal instability in obesity-associated oesophageal adenocarcinoma Yun Suen Kho, Aiswarya Nair, Daryl Kai Ann Chia, Supriya Srivastava, Jimmy Bok Yan So, Asim Shabbir, Li Ren Kong, Ashok R. Venkitaraman
• 4724 Elevated plasma trimethylamine-N-oxide (TMAO) levels correlate with better clinical and molecular responses in immunotherapy-treated resectable gastroesophageal cancer and pleural mesothelioma Rachel J. Keogh, Paul K. Lee, N.V. Rajeshkumar, Blair V. Landon, Joshua E. Reuss, Jaime Wehr, Gavin Pereira, Amna Jamali, Noushin Niknafs, Ronan J. Kelly, Ali H. Zaidi, Josephine L. Feliciano, Julie R. Brahmer, Vincent K. Lam, Patrick M. Forde, Chi V. Dang, Valsamo Anagnostou

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