In Vitro Models 2: 2D, 3D, Organoids, and Spheroids

• 2497 · PDF A human pcVMT platform for personalizing chemotherapy route and regimen selection in peritoneal carcinomatosis Aaqil M. Khan, Stephanie J. Hachey, Vinodh Kumar Radhakrishnan, Fatemeh Tajik, Melanie Roman, Christopher C. W. Hughes, Maheswari Senthil
• 4852 · PDF Unraveling the molecular events driving BRCA1 -associated transformation in novel models of early müllerian cancer Carly A. Tompkins, Victoria R. Cerda, Marcela Haro, Quentin Chartreux, Andrew J. Li, Simon A. Gayther, B.J. Rimel, Fabiola Medeiros, Kate Lawrenson
• 4853 · PDF A comprehensive endometrial cancer organoid biobank reveals subtype-specific transcriptional programs and therapeutic targets Mali Barbi, Shalini Gupta, Santhilal Subhash, Divya Gowthaman, Arielle Katcher, Megan Gorman, Brian Yueh, Erdogan Akyildiz, Uma Mahesh, Devin Gee, Nyasha Chambwe, Charlie Chung, Marina Frimer, Gary L. Goldberg, Semir Beyaz
• 4854 Mutational profiling of patient tumor organoids for clinical variable association and markers of therapeutic response in mucinous appendiceal cancers Daniel J. Gironda, Cecilia R. Schaaf, Steven D. Forsythe, R. Andrew Erali, Tiefu Liu, Ming Leung, Ashok K. Pullikuth, Helen R. Bernardirathgeb, Eleftherios Makris, Shay Soker, Edward A. Levine, Konstantinos I. Votanopoulos, Lance D. Miller
• 4855 · PDF Cystathionine beta-synthase drives transcoelomic metastasis in ovarian cancer Pallab Shaw, ARPAN DEY BHOWMIK, Akrit Pran Jaswal, Resham Bhattacharya, Priyabrata Mukherjee, Shailendra Kumar Dhar Dwivedi, Geeta Rao
• 4856 · PDF Quantifying the dual effect of anti-tumor and pro-tumor human neutrophils on natural killer cell behaviors in a microphysiological system Shuai Shao, Caroline N. Jones
• 4858 · PDF Combined pan and precision targeting in extrachromosomal DNA-positive gastric cancer Gengyi Zou, Melissa Pizzi, Aryanasingh Bhati, Bansi Vanparia, Wei-Chieh Yu, Ailing Scott, Yibo Fan, Calena Brown-Abel, Liyong Zeng, Johnson Amoah, Tanaya Alexander Washington, Yuan-Hung Lo, Vineet Bafna, Shilpa Dhar, Jaffer Ajani
• 4859 · PDF A novel sarcoma tumoroid platform preserving the tumor microenvironment to guide personalized immunotherapy Tony Ezzat, Nathaniel Ruppert, Elizabeth Nowak, Danny G. Cho, Masahiro Hitomi, Tyler E. Miller, Gary K. Schwartz, Jacob G. Scott, Zachary D. Burke
• 4860 · PDF Predicting therapy efficacy and revealing tumor heterogeneity using patient-derived 3D bioprinted ovarian cancer models Jiangang Zhang, Huiyu Yang, Ying Shan, Zihan Zhong, Ziren Kong, Yuning Sun, Huayu Yang, Lingya Pan, Yilei Mao, Ying Jin
• 4861 · PDF Modeling IDH-mutant low-grade astrocytoma using human embryonic stem cells Greta Henriette Ghita, Yanhong Yang, Viviane Tabar
• 4862 Development of a high-throughput multimodal patient-derived platform integrating autologous fibroblasts and tumor-infiltrating lymphocytes for colorectal cancer drug discovery Lewis Campbell, Agapitos Patakas, Athanasios Koulis, Hannah Findlay, Daria Paruzina, Cameron Fyfe, Ellen Main
• 4863 Innovative xeno free synthetic hydrogel supports iPSC derived intestinal organoids and colorectal cancer (CRC) organoid growth, An advanced organoid platform for therapeutic screening Kalhara R. Menikdiwela, JOHN HUANG
• 4864 · PDF A leiomyosarcoma cell model based on smooth muscle-committed TP53 -knockout iPSCs identifies novel actionable pathways. Annalisa Astolfi, Livia Gozzellino, Alice Costa, Ilenia Motta, Margherita Nannini, Maria Concetta Nigro, Martina Lops, Maria Giulia Pirini, Antonio De Leo, Gianandrea Pasquinelli, Maria A. Pantaleo
• 4865 · PDF Functional assessment of patient drug sensitivity using AI-powered image analysis on patient-derived organoids and micoorganoid spheres Abraham Lin, Maxim Le Compte, Divya L. Dayanidhi, Edgar Cardenas De La Hoz, Rebecca Stone, Tyler Gilcrest, Geert Roeyen, Filip Lardon, Christophe Deben
• 4866 · PDF Interactions between colorectal cancer cells and cancer-associated fibroblasts across desmoplastic reaction subtypes Wataru Kosaka, Keigo Murakami, Yota Akamori, Hideaki Karasawa, Yuki Yasuda, Ichiro Ise, Tomoyuki Ono, Megumi Murakami, Yoshihiro Sato, Gumpei Yoshimatsu, Hideyuki Suzuki, Takashi Kamei, Shinobu Ohnuma, Toru Furukawa, Michiaki Unno
• 4867 · PDF The radiosensitivity index (RSI): A patient-derived organoid platform for predicting radioresistance in cervical cancer Young Joo Lee, Ju Hee Oh, Eun Hye Choi, Kyung Jin Eoh, Sang Wun Kim, Yoo-Na Kim, Ji Hyun Lee, Eun Ji Nam
• 4868 Modelling glioblastoma sensitivity to irradiation with a patient derived xenograft-derived 3D platform Fu-Ju Chou, Annamaria Rapisarda, Marianna Zipeto, Michael Ritchie, Markus Hippich, Daniel Ciznadija, BanuPriya Sridharan, Veena Jagannathan, Gilad Silberberg, Stefano Cairo
• 4870 · PDF Isolation, characterization and establishment of male breast cancer cells from male breast cancer patient-derived tumor (PDT) Samikshya Kandel, Kathy Robinson, Ricardo Cosyleon, Daotai Nie, Krishna A. Rao
• 4872 · PDF 3D bioprinting of fresh NSCLC: The Lung3Dprint proof of concept study Aurélie Cadiou, Clarisse Thiollier-Schmitt, Gabrielle Devret, Raphaële Guelminger, Tanguy Fenouil, Corinne Perrin, Camille Leonce, Samantha Ballesta, Gaëtan Pochon, Nicolas Alcala, Lars Petter Jordheim, Charles Dumontet, Michaël Duruisseaux
• 4873 Reconstructing drug-tolerant persister (DTP) niches in iPSC-derived alveolar lung cancer organoids for spatio-temporal dissection of cell-cell interactions and ligand-receptor targets Toshio Suzuki, Harry Choi, Erik Johansson, Tetsuharu Nagamoto, Ayako Suzuki, Takuji Suzuki, Katsuya Tsuchihara, Yutaka Suzuki, Yuki Yamamoto
• 4874 · PDF Preclinical assessment of HER2 CAR-T cells using tumor and GI organoid models to define therapeutic window Julia B. Schueler, Ina Rohleff, Tania Martianez Canales, Kanstantsin Lashuk, Youri von Elsswilk, Namrata Jayanth, Ludovico Buti
• 4876 · PDF Cytokine supplementation for improved tumoroid-immune cell co-culture Shyanne Salen, Colin D. Paul, Sydney Hawkins, Matthew R. Dallas, David Kuninger
• 4877 · PDF A high-throughput 3D tumor-immune co-culture platform for evaluating immune checkpoint inhibitors Laure-Anne Ligeon, Tabea Gamma, Zuzanna Kotkowska, Charlotte Veser, Irina Agarkova, Sue Grepper, Madhu Nag-LAL
• 4878 · PDF Modeling tumor microenvironment-mediated resistance in NSCLC using a high-throughput spheroid microarray platform Alireza Rahnama, Maddalena Arrighi, Ines Pulido Endrino, Takeshi Shimamura, Ian Papautsky
• 4879 · PDF Bladder cancer organoids as a translational models to model disease biology and assess new therapies Emilie Decaup, Céline Rouget, Amandine Prioux-Quartier, Claire Béraud, Nadège Bidan, Xavier Gamé, Philippe Lluel
• 4880 · PDF An in-vitro vascularized micro-tumor model of cervical cancer Daniela Gaebler, Christopher C. W. Hughes, Stephanie J. Hachey
• 4881 Fabrication and characterization of echogenic microbubbles for in vitro modeling of blood-brain barrier (BBB) disruption via focused ultrasound Nathan Han, Nabhan Fakrudin, Frederic Zenhausern, Jian Gu

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