Vaccines and Other Immunomodulatory Agents

• 6690 · PDF Unfavorable early progression-free survival of immunotherapy compared to chemotherapy in bladder cancer: A meta-analysis of randomized trials Donghwi Choi, Hangyul Lee, Jinha Kim, Young Kwang Chae
• 6691 · PDF Pattern of inferior early progression-free survival with immunotherapy versus chemotherapy in head and neck cancer: A meta-analysis of randomized trials Donghwi Choi, Hangyul Lee, Jinha Kim, Young Kwang Chae
• 6692 · PDF Self-adjuvanting alpha-helical polypeptide simultaneously delivers neoantigen mRNAs and activates dendritic cells to eradicate tumors Jiadiao Zhou
• 6693 · PDF KLRG1 + PD-1 + CD8 + T cells drive potent antitumor immunity induced by a systemic STING nanovaccine Shuang Chen, Shuyue Ye, Qiang Feng, Gang Huang, Animesha Krishnamurthy, Baran Devrim Sumer, Jinming Gao
• 6694 · PDF Monocyte-derived dendritic cells for antigen-specific T cell activation Kaitlin Hsu, Jessica Voce, Amy Zhao, Jessie Ni
• 6695 · PDF Early progression disadvantage of immunotherapy-only treatment versus chemotherapy in NSCLC: A meta-analysis of randomized controlled trials Jinha Kim, Hangyul Lee, Donghwi Choi, Young Kwang Chae
• 6696 · PDF A senescent whole-cell vaccine platform derived from conditionally reprogrammed primary tumor cells primes potent T-cell immunity and overcomes ICI resistance in murine breast cancer models Sara Rasouli, Chongwen Cao, Weiyi Gong, Haichang Li, Bei Liu, Anna Vilgelm, Jenny Li, Xuefeng Liu
• 6697 · PDF Pelareorep combined with atezolizumab and chemotherapy shows immune conversion activity in advanced pancreatic cancer: Biomarker results of cohort 1 of the GOBLET trial Hendrik Schürmann, Sven-Thorsten Liffers, Richard Trauger, Thomas Heineman, Dirk Arnold, Jens T. Siveke
• 6698 · PDF EpitopeMiner: Scalable knowledge mining for evidence-driven personalized cancer vaccine design Agamjyot Singh Chadha, Isaac Jiasheng Cheong, Marcia Zhang, Wei Kit Tan, Wei Lin Tang, Jing Quan Lim, Solomonraj Wilson, Choon Kiat Ong, Bernett Lee, Chwee Ming Lim, Olaf Rotzschke, Mai Chan Lau
• 6699 · PDF Novel preclinical immunocompetent mouse model for assessment of immunotherapies targeting cGAS-STING axis Angela Pappalardo, Philippe De La Rochere, Patricia Isnard-Petit, Gaëlle H. Martin, Fabiane Sonego, Kader Thiam
• 6700 · PDF A fully integrated set of in vitro and in vivo tools for utilization of micro-organisms as new therapeutic weapons against cancer Guillaume Serin, Lucie Demontoux, Elizabeth Bertrand, Marie Leblanc, Sylvie Maubant, Ismahene Benzaid, Marc Hillairet De Boisferon
• 6701 · PDF Re-engineering cancer vaccines: Bria-OTS+ integrates innate and adaptive immunity for broad and persistent anti-tumor responses Miguel A. Lopez-Lago, Pravin Kesarwani, Vikas Bhardwaj, Xiaoyi Zheng, Ying Liu, Sagarika Pachhal, Patience cournoo, Renee Cortez, George Woodfield, Charles Wiseman, William V. Williams
• 6702 · PDF A Cxcl10 mRNA-LNP adjuvant enhances immune checkpoint inhibitor responses in melanoma models Kaitlyn M. Landreth, Katherine Lee, Emel Sen Kilic, Joshua Chapman, Mary Garland-Kledzik, F. Heath Damron, Tracy W. Liu
• 6703 · PDF Rg002: An mRNA-LNP-based immunotherapy targeting HPV-16/18-related malignancies Shan Cen, Lan Zhu, Fei Chen, Wei Wang, Lihua Qiu, Hua Yang, Yijie Dong, Weiguo Zhang, Huizhen Zhang, Jing Wang
• 6704 · PDF Exercise attenuates anti-PD-1-induced adventitial macrophage inflammation in the aorta of aged melanoma-bearing mice Jonghae Lee, Sumedha Pareek, Truong Lam, Fei Wang, Guanshu Liu, Jared K Burks, Jun-ichi Abe, Keri Schadler
• 6705 · PDF A versatile coacervate based delivery system to overcome engineering barriers in immune cells Renxia Zhang, Peipei Zhu, Manman Lu, Qing Zhang, Lihong Jiang, Xiaowen Fei, Xiaofei Gao
• 6707 Developing oncolytic measles virus expressing MG53 for the treatment of lung cancer Zhongguang Li, Cheng Chih Hsu, Fei Jiang, Matthew Bu, Ellica Leong, Umme Lubaba, Xuefeng Liu, Jianrong Li, Haichang Li
• 6708 · PDF Neoadjuvant pembrolizumab with therapeutic DNA vaccine reshape intratumoral immunity in a phase 2 trial of HPV-positive HNSCC Hye Ryun Kim, June-Young Koh, Chang Gon Kim, Min Hee Hong, Hyun Jun Hong, Dahee Kim, Nam Suk Sim, Sun Och Yoon, Gamin Kim, Wonrak Son, Yeju Kim, Chang Geol Lee, Kyung Hwan Kim, Jeong Seok Lee, Chan-Young Ock, Yoon Woo Koh
• 6709 · PDF Temporal trends in biomarker utilization across 24,000+ immuno-oncology trials Fahad Benthani, Samik Upadhaya, Cynthia L. Neben, Kellie R. McDonald, Alicia Y. Zhou
• 6710 Development of T cell activating nucleic acid fusion vaccine to prevent metastatic uveal melanoma establishment Vitali Alexeev, Mizue Terai, Sergei Koshkin, Takami Sato
• 6711 · PDF Investigating MyD88 and NLRP3 pathway modulation in a TLR4 and TLR9 driven immunotherapy in a murine model of ovarian cancer Ania V. Klas, Rita E. Serda
• 6712 Promoting improved agnostic cross presentation of tumor antigens with an oncolytic adenovirus expressing bispecific macrophage engagers Ahmet Hazini, Margarida Rei, Natanya Cartwright, Ricardo A. Fernandes, Kerry Fisher, Len Seymour
• 6713 · PDF Engineering a hydrogel-based vaccine to prevent recurrence in pancreatic ductal adenocarcinoma Peter Yuxin Xie, James P. Agolia, Rosyli F. Reveron-Thornton, Chuner Guo, Maria Moozhiyil Korah, Andrea Delitto, Deshka Foster, Ovijit Chaudhuri, Daniel Delitto
• 6714 · PDF Humanized SLE mouse model for evaluating B-cell CAR-T therapy efficacy and safety Ruowen Zhang, Thi Minh Thi Ho, Bo Peng, Hongjing Qu, Qi Jiang, Benjamin Wei, Qingcong Lin
• 6715 Safety, tolerability, and early immune responses in the safety run-in of an HER2 multi-epitope vaccine combined with T-DM1 in residual HER2-positive breast cancer Saranya Chumsri, Sharmila Giri, Andy J. Ness, David W. Hillman, Nadine Norton, Davitte Cogen, Brian M. Necela, Aziza Nassar, Donald W. Northfelt, Pooja Advani, Rohit Rao, Alvaro Mareno-Aspitia, Brenda Ernst, Kathryn J. Ruddy, Matthew P. Goetz, Keith L. Knutson
• 6716 · PDF ALK-mRNA vaccine as a new Immunotherapy for ALK+ cancers Gabriele Saccu, Alessandro Gasparetto, Carmen Mecca, Elisa Bergaggio, Simone Piane, Taek-Chin Cheong, Nirmala Tilija Pun, Roberto Chiarle
• 6717 · PDF Preclinical study of armored claudin 18.2 nanobody CAR NK cells targeting gastric cancer Byeong-Hyeok Choi, Ga-Ram Hwang, Morgan Flaherty, Vincent M. DeStefano, Masayuki Wada, Kevin Pinz, Jennifer E. Chow, Nabil Hagag, Yu Ma, Jing Luo, Yupo Ma
• 6718 · PDF Identifying new cell surface markers of T-cell reactivity through single cell transcriptomic analysis Abraham A. Hakim, Lisa Kenney, Nivedita Mohan Ratnam, Jared J. Gartner, Ian S. Goldlust, Aarushi Bhasin, Brian Bui, Nicholas D. Klemen, Steven A. Rosenberg, Frank J. Lowery

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