Cell Death Pathways and Treatment

• 5663 Chemotherapy-induced galectin-1 derives drug-tolerant persister state associated EMT in triple negative breast cancer with targetable vulnerability to ferroptosis inducers Shagufa A. Ehtesham Shaikh, Kedar Sharma, Dipti Bhattacharya, Vaibhav Kothari, Samruddhi Jadhav, Nandini Verma
• 5664 · PDF Targeting cholangiocarcinoma with ferroptosis-inducing siRNA-based nanotherapeutics Peyton Classon, Danielle Marie Carlson, Jayla Millender, Irene Yan, Sumera Ilyas, Rory L. Smoot, TUSHAR PATEL, Gregory J. Gores, Davide Povero
• 5665 · PDF Levistolide A inhibits bladder cancer progression by suppressing GPX4 expression and activating ferroptosis Yixi Gong, Jihye Kim, Ingyu Lee, Xiaoyu Guo, Bomi Han, Eui Man Jeong
• 5666 · PDF Tambiciclib (SLS009), a CDK9 inhibitor, promotes apoptosis and suppresses MCL-1 levels in AML cell lines Elizabeth C. Trull, Philip C. Amrein
• 5667 · PDF Ferroptosis necessitates caspase 5 dependent GSDME cleavage in ovarian cancer Mahmuda Akter, Lei Sun, Cheng Chi, Shuang Huang
• 5668 · PDF USP7 and ITCH/UBE4B ubiquitin ligase regulate the switch between apoptosis and necroptosis via Ku70 and c-FLIPL polyubiquitination in neuroblastoma Christophe Le Clorennec, Carla Sampaio, Peter E. Zage
• 5669 · PDF Investigating the role of TRPM4 in the cancer cell death induced by ErSO and derivatives Brooke A. Bouwens, Michael P. Mulligan, Rowan Glover, Paul J. Hergenrother
• 5670 · PDF Oxidative stress-mediated non-apoptotic, non-autophagic cell death: A mechanistically distinct strategy to overcome resistance in colorectal cancer cells Mati Ur Rehman, Almuayyad Gajani, Mahwish Fatima, Paras Jawaid, Arooj Shafiq, Azhar Hussain Rajabali
• 5671 · PDF Mitotic entry with DSB induces pyroptosis through 53BP1-mediated NLRP3 inflammasome activation Mengshi Luo, Yuewen Zhang, Wenjian Gong, Zhiqi Liao, Linghui Wang, Qiuyang Xu, Xingzhe Liu, Yijie Wu, Xuejiao Zhao, Gorden B. Mills, Ding Ma, Guangnian Zhao, Qinglei Gao, Yong Fang
• 5672 · PDF PRMT5 inhibition enhances therapeutic vulnerability to Bcl-xL/Bcl-2 inhibitors in glioblastoma Shumpei Onishi, Ashis Chowdhury, Jean-Paul Bryant, Dragan Maric, Qi Li, Jing Wu, Yeshavanth Kumar Banasavadi-Siddegowda
• 5673 · PDF Ferroptosis induction synergizes with KRAS inhibitors in KRAS -mutant lung adenocarcinoma Amirali Karimi, Yu Qian, David Molkentine, Alvaro Guimaraes Paula, Busra Ernhofer, David Hwa Peng, Monique B. Nilsson, John V. Heymach
• 5674 · PDF CD47 blockade induces necroptosis and complements the effects of BCL-2 inhibition in hematologic malignancies Stephen Jun Fei Chong, Rebecca Valentin, Jing Wang, Fen Zhu, Filip Garbicz, Kartini Iskandar, Brienne C. Y. Toh, Marisa Peluso, Jeremy Zhang, Liam Hackett, Benjamin H. Lee, Li Ren Kong, Catherine J. Wu, Wee Joo Chng, Shazib Pervaiz, Carsten U. Niemann, Ruben D. Carrasco, Matthew S. Davids
• 5675 · PDF MUC1-C-directed exatecan ADC induces genotoxic stress and transcriptional suppression of UPR-inflammatory pathways in metastatic colorectal cancer Surender Kharbanda, Deepak Raina, Rehan Ahmad, Changchuin Mao, Sourav Choudhary, Brian Lawney, Nandita Sreenivasalu, Govind Panchamoorthy, Ravi Jasuja
• 5676 · PDF Bites that kill: Understanding cancer cell fate after macrophage mediated trogocytosis Ishwaree Datta, Meghan Morrissey, Annie Rogers
• 5677 · PDF GPX4-FTH1-ARNT signaling regulates iron efflux to suppress ferroptotic cell death and promote immune remodeling in osteosarcoma Md Abdullah, Donghee Lee, Jong Hyuk Kim
• 5678 · PDF Cuproptosis induction in TP53-mutated acute myeloid leukemia Yuju An, Xinghan Zeng, Brandy Perkins, Nour S. Naji, Yanyan Wang, Booseong Seo, Yashvi Hemani, Frederick Bunz, Theodoros Karantanos
• 5679 · PDF LIFR inhibition with EC359 triggers ferroptosis to overcome chemoresistance in endometrial cancer Emily Jean Aller, Baskaran Subramani, Xue Yang, Paulina Ramirez, Bindu Santhamma, Hareesh B. Nair, Edward Kost, Ratna K. Vadlamudi, Suryavathi Viswanadhapalli
• 5680 Hinokitiol targets metal and redox vulnerabilities in liver cancer Daniela Delgado, Anyssa Rodriguez, Subhash C. Chauhan, Nirakar Sahoo
• 5681 · PDF Mechanism of mitochondria-independent cuproptosis Martin Mistrik, Martin Loffelmann, Petr Dzubak, Marian Hajduch, Josef Srovnal, Zdenek Skrott, Lucie Beresova, Tomas Pluhacek, Petr Tarkowski
• 5682 · PDF Elucidating and overcoming therapeutic resistance in esophageal adenocarcinoma Naren Li, Jessica Ji, Jaylon C. Aggison, Siqi Wu, Francisco A. Molina-Pelayo, Cristian G. Medina, Ritika Raj, Yuan Xu, Robert T. Ripley

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