Molecular Targets 2

• 5712 · PDF Virtual screening identification of FDA approved drugs blocking the therapeutic action of tumor-specific amplitude-modulated radiofrequency electromagnetic fields Hugo Jimenez, Ping Dou, Aaban A. Azmi, Elyas Khan, Alhussein Elshebiny, Yusuf Fateh, Nathan Elias, Cameron Osenkowski, Liyue Zhang, Grayson Barker, Allan M. Johansen, Ravi Paluri, Janaka S. S. Liyanage, Mohammed N. Al Hallak, Anthony F. Shields, Muhammad W. Saif, Husain Y. Khan, Amro Aboukameel, Md Hafiz Uddin, Sahar F. Bannoura, Ramzi M. Mohammad, Alexandre Barbault, Boris C. Pasche
• 5713 Comparative performance of amplicon-based DNA and RNA NGS co-detection versus hybrid-capture DNA-NGS for SNV/INDEL profiling in Chinese NSCLC driver genes Zefeng Xie, Yuze Zhao, Haitao Li, Yu Li, Yulan Chen, Meilian Liu, Xuyuan Li
• 5714 Amplicon-based DNA and RNA co-detection improves ROS1 fusion identification across Chinese solid tumors compared with hybrid capture DNA-NGS Meiyi Li
• 5715 · PDF Histone-modifying enzymes in androgen-deprived prostate cancer: EZH1 as a synergistic therapeutic target Tanaya Purohit, Emily Schmitt, Zachary Schultz, Marcelo Bigarella, Kayla Bahr, Mohammad Rizvi, Diana Garcia, Sean Sardeson, Erika Heninger, Shannon Reese, Jacob Popp, Joshua M. Lang, Karla Esbona, Wei Huang, Peter W. Lewis, John M. Denu, Bing Yang, David F. Jarrard
• 5716 Establishing a drug-target relationship between doxycycline/methacycline and acetylated KLF5 in bone-metastatic prostate cancer Duo Zhang, Xinyuan Jiang, Yutian Ren, Yujing Qin, Shiqi Deng, Qifan Zhou, Yuanguang Chen, Zhiqian Zhang, Xumu Zhang, Jin-Tang Dong
• 5717 · PDF Identifying the regions responsible for isoaspartylation and aggregation of SCLC antigen ELAVL4 Shiori Fukutome, Diego Alejandro Velarde, Chunli Yan, Whitaker Cohn, Nazarius Lamango, Ite A. Offringa
• 5718 · PDF Cbx5 as a potential target to enhance immunotherapy in small cell lung cancer Hong Cao, Yiting Li, Jiajia Gu, Yuan Hao, Ziyang Wang, Benjamin A. Nacev, Kwok-Kin Wong, Hua Zhang
• 5719 · PDF Contrasting roles of MSH2 and MLH1 in basal-like breast cancer Tanzia Islam Tithi, Jiao Mo, Nicholas Borcherding, Sung Jo, Heather R Kates, Chandra Maharjan, Seyedehalaleh Anvar, Richard L. Bennett, Jixiu Shan, Rohan A. Desai, Kailey E Cash, Masayoshi Honda, Lei Wang, Kawther K. Ahmed, Kalyanee Shirlekar, Li Chen, Katherine N. Gibson-Corley, Ronald Weigel, Jonathan D. Licht, Maria Spies, Ryan Kolb, Weizhou Zhang
• 5720 · PDF High TROP2 expression is frequent and linked to nodal metastasis in head and neck cancer David Dum, Juliana Knief, Christoph Thorns, Morton Freytag, Florian Lutz, Waldemar Wilczak, Katharina Möller, Florian Viehweger, Fiete Gehrisch, Nina Schraps, Claudia Hube-Magg, Martina Kluth, Maria Christina Tsourlakis, Ronald Simon, Guido Sauter, Natalia Gorbokon, Munir Hamad, Nikolaus Möckelmann, Till Clauditz, Adrian Münscher, Viktoria Chirico
• 5721 · PDF Aldehyde dehydrogenase inhibition as a strategy to overcome drug-refractory multiple myeloma Michael J. Ingling, Robert Chitren, Krishne Gowda, Shantu Amin, Subash C. Jonnalagadda, Tulin Budak-Alpdogan, Manoj Pandey
• 5722 · PDF Protein regulator of cytokinesis 1 (PRC1) promotes Wilms tumor progression by orchestrating tumor-stromal crosstalk Qiushi Wang, Tianshun Zhang
• 5723 · PDF TMEM165-CLOCK fusion protein drives metastasis through enhanced lysosomal exocytosis Youngkeun Lee, Ji-yoon Choi, Min-jeong Kim, Sung Wook Seo
• 5724 · PDF HMGB1 overexpression is a strong and independent prognostic feature in ERG negative prostate cancer Neele Heckmann, Nicolas Hertzsprung, Christian Bernreuther, Eike Burandt, Florian Lutz, Clara Lühr, Clara von Bargen, Martina Kluth, Maria Tsourlakis, Nina Schraps, Fiete Gehrisch, Ronald Simon, Hans Heinzer, Alexander Haese, Henning Plage, Sarah Minner, Guido Sauter, Thorsten Schlomm, Markus Graefen, Cosima Völkl
• 5725 · PDF Targeting Rac1 as a therapeutic vulnerability in T-cell lymphomas Lucero Alvarado, María M. Debernardi, Gonzalo Gonzalez, Helena Andrea Sterle, Valeria G. Sanchez, Silvina Palmer, Sofia Rivarola, Jorgelia Real, Barrozo Julio, Goergina A. Cardama, Florencia Cayrol
• 5726 · PDF Targeting canine bladder cancer with Nimbolide, a Neem ( Azadirachta indica ) limonoid Conner Suen, Eashan Sharma, Gabriel Gilchrist, Neelu Batra, Christopher A. Lucchesi, Kenneth A. Iczkowski, Robert B. Rebhun, Paramita M. Ghosh
• 5727 · PDF MTAP deficiency is common in head and neck tumors but dependent on the site of tumor origin Juliana Knief, Christoph Thorns, Morton Freytag, Florian Lutz, Viktoria Chirico, David Dum, Waldemar Wilczak, Katharina Möller, Florian Viehweger, Fiete Gehrisch, Nina Schraps, Claudia Hube-Magg, Martina Kluth, Maria C. Tsourlakis, Ronald Simon, Guido Sauter, Natalia Gorbokon, Munir Hamad, Nikolaus Möckelmann, Till Clauditz, Adrian Münscher
• 5728 Amplicon-based DNA and RNA NGS co-detection enhances ROS1 fusion detection and partner diversity compared with hybrid-capture DNA-NGS in Chinese NSCLC Yang Zebo
• 5729 · PDF Discovery of tumor-specific antigens in melanoma tissue biopsies via integrated proteogenomic analysis Arthur Viodé, Daniel Gautheret, Anamarija Pfeiffer, Hughes Hermann, Sharane Muralli, Séverine Roy, Antoine Meant, Amaury Lachaud, Yuehan Feng, Caroline Robert
• 5730 · PDF CDX1 binding to the PVT1 exon 9-associated promoter drives oncogenic PVT1 exon 9 overexpression in aggressive prostate cancer Chinedum C. Udekwu, Siti K. Nuraziza, Seidu Adams, Rachel E. Bonnaci, E. Oluwabunmi Olapade-Olaopa, Olorunseun O. Ogunwobi
• 5731 · PDF ID4 maintains undifferentiated and immune-evasive states in aggressive triple-negative breast cancer and represents a novel druggable vulnerability Lautaro Rivera, Carla Toro, Juan Manuel Fernandez, Jochen Maurer, Maria Teresita Branham
• 5732 · PDF Identification and functional analysis of chloride intracellular channel protein 1-binding peptide and its uses for ProTac-based cancer therapy Aryeong Lee, Byungheon Lee
• 5733 · PDF Decoding ELAVL4 isoaspartylation in SCLC using engineered PCMT1: A strategy for uncovering immune triggers Davin Pan, Shiori Fukutome, Xuhan Zhou, Diego De Luna Moran, Chunli Yan, Diego Alejandro Velarde, Whitaker Cohn, Ite A. Offringa
• 5734 · PDF Targeting exportin 1 reduces cutaneous squamous cell carcinoma growth alone and in combination with 5-fluorouracil Moynul Islam, Justin Rudd, Louise Monga, James Grunkemeyer, Laura Hansen
• 5735 Imiquimod targets tankyrase 2 to suppress wnt-active colorectal cancer Philemon Ubanako, Ramesh Pandian, Adedapo Adeyinka, Bernice Monchusi, Clement Penny
• 5736 · PDF BMAL2 maintains DNA integrity via regulating homologous recombination to promote ovarian clear cell carcinoma tumorigenesis Grace Yin Tze Tan, Pei-Yi Lin, Li-Tzu Cheng, Wendy Wenhua Hwang-Verslues
• 5737 · PDF Developing agents to target IL-8 signaling and intercept progression to esophageal adenocarcinoma Yun Zhang, Andrew Alt, Nick Santoro, Shari Barnett, Kiran Lagisetty, Jules Lin, Rishindra M. Reddy, Chigozrim Ekeke, Andrew Chang, David Odell, Laura A. Kresty
• 5738 · PDF Beyond bulk: Resolving RNASeq/mass spectrometry/IHC discrepancies with multiplexed spatial profiling and 3D cluster analysis to refine HER3 (bs)Ab and (bs)ADC therapeutic strategies Jeannette Fuchs, Christophe Mas, Eric Durandau, Diana Rocha Gomes, Min Ma, Antoine Attinger, Anna Pokorska-Bocci
• 5739 · PDF Defining sodium channel isoforms in oral squamous cell carcinoma in vitro Kelly Jean Sherman, Alexis Gray, Dennis Paul

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