Genetic and Transcriptomic Dissection of Cancer Evolution

• 5913 · PDF Integrative transcriptomic profiling reveals stromal activation patterns in gastric cancer beyond HER2 status Woo Sun Kwon, Chan Hee Park, Sejung Park, Choong-Kun Lee, Poh Zhong Wee, Jia Hui Liew, Jingming Chew, Sun Young Rha
• 5915 · PDF Utility of long-read RNA-sequencing for isoform and fusion discovery in lung cancer Kevin Levine, Colette Felton, Tanvi Damle, Christina Baik, Angela Norie Brooks, Alice H. Berger
• 5917 Single-cell profiling of NK cells in chronic myeloid leukemia identifies distinct cell states with gene regulatory signatures associated with differential outcomes after imatinib discontinuation Santoshi Borra, Da Yan, Robert S. Welner, Zongliang Yue
• 5918 · PDF Single cell functional characterization of cancer mutations and their cellular phenotype Huiyun Sun, Dongin Lee, HoJoon Lee, Susan M. Grimes, Raegan Wood, Hanlee P. Ji
• 5919 · PDF Dissecting gene regulation of cellular states in glioblastoma using single-cell multi-omics Min Yang, Nicolas L. Gonzalez Castro, Alexander Jucht, Sophia Kovatsis, Channing Pooley, Sydney Dumont, Kevin Johnson, Julie Laffy, Bo Xia, Roel Verhaak, Itay Tirosh, Mario Suva
• 5921 · PDF Cell type-specific mapping of endometrial cancer risk genes using single-nucleus multi-omics Preety Bajwa, Carly Chapman, Dylan Glubb, Tracy O'Mara
• 5922 · PDF Single-cell mapping of the colon epithelium reveals a pre-malignant stem cell that defines early transformation risk Yujin Lee, Moray J. Campbell, James C. Fleet
• 5923 · PDF Optical pooled CRISPR screening coupling multiplexed guide RNA detection and single-cell spatial multi-omics Yi Cui, Marena I. Trinidad, Nurel Arriaran, Isabel Lee, Chia-Ying Lee, Shanshan He, Timothy Riordan, Joseph Beechem, Alexander E. Ehrenberg, Hanqin Li
• 5924 · PDF Single-cell full-length transcriptome of lung cells reveals genetic effects on isoform regulation beyond eQTL Bolun Li, Thong Luong, Elelta Sisay, Jinhu Yin, Zixuan Zhang, Ju Hye Shin, Jinyoung Byun, Yoon Soo Chang, Maria Teresa Landi, Nat Rothman, Erping Long, Qing Lan, Christopher I. Amos, Tongwu Zhang, Jianxin Shi, Nicholas Mancuso, Haoyu Zhang, Jin Gu Lee, Eon Young Kim, Jiyeon Choi
• 5925 Diagnostic concordance of WHO 2021 standards, WGS, and DNA methylation classification in diffuse gliomas: A single-center cohort study Jungyu Kim, Yongjae Lee, Jeong Seok Lee, Tae Hoon Roh, YOUNG SEOK JU
• 5926 · PDF Overcoming low SEPTIN14 expression to detect EGFR-SEPTIN14 fusion in RNA sequencing Suhyun Hwangbo, Sungyoung Lee
• 5927 · PDF Integrative analysis of EMT and hippo pathway activity in gastric cancer peritoneal metastasis Juin Park, Woo Sun Kwon, Chan Hee Park, Tae Soo Kim, Jingmin Che, Sun Young Rha
• 5929 · PDF Global mRNA 3'UTR lengthening in small-cell neuroendocrine carcinoma Yi Zhang, Xiaofan Zhao, Ya-Mei Hu, Xiao-Xin Sun, Faming Zhao, Nicole Andeen, Rosalie C. Sears, Jonathan R. Brody, Joshi J. Alumkal, Gordon B. Mills, Mushui Dai, Zheng Xia
• 5930 · PDF Spatial transcriptomics of colonic neoplasia presenting mucinous adenocarcinoma with genetically-engineered mouse model Haruki Sada, Hiroaki Niitsu, Hikaru Nakahara, Masashi Miguchi, Hirotaka Tashiro, Hideki Ohdan, Takao Hinoi
• 5931 · PDF Modeling of bladder cancer evolution from field effects by multi-platform spatial mapping on the whole-organ scale Bogdan A. Czerniak, Sangkyou Lee, Khanh Ngoc Dinh, Huiqin Chen, Yishan Wang, Jiansong Chen, June Goo Lee, Sung Yun Jung, Nagireddy Putluri, Neema Navai, David McConkey, Charles Chuanhai Guo, Peng Wei, Marek Kimmel
• 5932 Cell free DNA based genomic analysis revealed the distinct whole genome landscape and chronology of intravascular large B cell lymphoma Takuto Mori, Kazuyuki Shimada, Kaito Mimura, Suguru Fukuhara, Koji Izutsu, Daisuke Kawauchi, Yoshitaka Narita, Akiko Miyagi Maeshima, Ryosuke Koyamada, Nobuhiro Hiramoto, Hirona Maeda, Nobuyuki Kakiuchi, Ai Okada, Kenichi Chiba, Yuichi Shiraishi, Akifumi Takaori−Kondo, Seishi Ogawa, Akihiro Tomita, Kenichi Yoshida
• 5933 · PDF Whole-genome sequencing of lung neuroendocrine neoplasms reveals a TP53 WT / RB1 WT subtype with CCND amplification Minjun Ha, Kwon Joong Na, Soyeon Kim, Miso Kim, Bhumsuk Keam, Tae Min Kim, Dong-Wan Kim, Jeonghwan Youk, Young Tae Kim
• 5934 Genomic signatures of chromosomal instability from a pan-cancer landscape of haplotype-specific copy-number alterations Chunyang Bao, Matthew Leventhal, Hansol Park, Gang-Hee Lee, Ryul Kim, Won-Chul Lee, Jonghoon Lee, Yoonsuh Lee, Beomki Lee, David Lehotzky, Ron Solan, Antonia Kowalewski, Xavi Loinaz, Vasuki Narasimha Swamy, David I. Heiman, Samantha Van Seters, Saveliy Belkin, Sam Wiseman, Andrew D. Cherniack, Luis Antonio Corchete Sanchez, Brian P. Danysh, Zachary Everton, Chip Stewart, Haruna Tomono, Gengchao Wang, Esther Rheinbay, Gad Getz, Cheng-Zhong Zhang, Young Seok Ju
• 5935 · PDF Accurate detection of DNA variants and ecDNA from prostate FFPE biopsies using LinkPrep Shiting Li, Alexander Fortuna, Rahul Mannan, John Zachary Sanborn, Yuping Zhang, Xuhong Cao, Natalie Fredriksson, Lisa Munding, Saravana M. Dhanasekaran, Marcin Cieslik Cieslik, Arul M. Chinnaiyan
• 5936 · PDF Massively parallel installation and evaluation of cancer coding mutations Xiaoyu Zhao, Isabella Panagiotou, Rachel Collier, Catalina Fogg, Katherine Licon, John J. Y. Lee, Dylan Fong, Jing Chen, Paulina Rios, Ondine Atwa, Samuel I. Gould, Ingoo Lee, Jiahao Gao, Francisco J. Sánchez-Rivera, MARCUS R. KELLY, Trey Ideker
• 5937 · PDF Panorama of chromosomal instability in 1209 lung cancer genomes YANG YANG, Tongwu Zhang, Lixing Yang, Maria Teresa Landi
• 5938 · PDF High-resolution multi-omic dissection of bone marrow in TP53-mutant acute myeloid leukemia Gonzalo Lopez Garcia, Felix Andreas Radtke, Sagnik Banerjee, BIJAY JAISWAL, Daiane Hemerich Brennan, Yilin Zhao, Verena Körber, Marlen Metzner, Rachel Moore, Bilyana Stoilova, Junfei Zhao, Bettina Nadorp, David Cruz Hernandez, Batchimeg Usukhbayar, Aimee O’Donohue, Maria Ortiz Estevez, Daniel Lopes de Menezes, Rajasekhar NVS Suragani, Paresh Vyas, Anita Gandhi
• 5939 A large-scale sequencing study identifies a novel non-coding structural variant as a high-penetrance susceptibility variant for melanoma Linh T. Bui-Raborn, Lorenza Pastorino, Donato Calista, Huu Phuc Hoang, Bruna Dalmasso, Jessica Scales, Sophie Papiernik, Xiaoyu Wang, Rohit Thakur, Stefania Pellegrini, Mai Xu, Joshuah Yon, William Bruno, Tongwu Zhang, Zaida García-Casado, Enrica Teresa Tanda, Francesco Spagnolo, Monia Di Prete, Irene Bottillo, Siranoush Manukian, Maria Chiara Scaini, Katerina P. Kypreou, Lucia Di Nardo, Miriam Potrony, Paula Aguilera-Peiró, Nesreen Shahrour, Tam-Anh Tran, Weiyin Zhou, Wen Lou, Aurélie L. Vogt, Jia Liu, Kristine Jones, Monica Rodolfo, Irene Stefanaki, Cristina Pellegrini, Carlo Cota, Chiara Menin, Maria Concetta Fargnoli, Ketty Peris, Susana Puig, Eduardo Nagore, Paola Grammatico, The Melanostrum Consortium, Jianxin Shi, Paola Ghiorzo, Kevin M. Brown, Maria Teresa Landi
• 5940 Chromosome-level phasing to resolve haplotypes using multiomic data in multiple myeloma reveals complex distal interactions between chromosomes that impacts epigenetic states and gene expression Nathan J. Becker, Enze Liu, J. Zachary Sanborn, Attaya Suvannasankha, Kelvin Lee, Dickran Kazandjian, Benjamin Diamond, Abhishek Pandey, Rafat Abonour, Ola Landgren, Elizabeth M. Munding, Aneta Mikulasova, Brian A. Walker
• 5941 · PDF Large-scale analysis reveals distinct molecular subtypes in real-world gastric cancer data Akul Singhania, Swati Kaushik, Brandon L. Mapes, Lee F. Langer, Kayla R. Bastian, Samantha Cowher, Yaakov E. Stern, Bo Hu, Gonzalo Lopez, Ruslan Novosiadly, Maria Ortiz-Estevez, Kai Wang, Nick Callamaras, Richard A. Klinghoffer, Justin Guinney, Radia M. Johnson
• 5942 · PDF Longitudinal liquid biopsy profiling in breast cancer patient: Clinical utility and guidelines Aurelia Robert, Alexandre Xu-Vuillard, Thomas Grinda, Antoine Italiano, Christophe Massard, Elie El-Rassy, Adrien Mouren, Alessandro Viansone, Barbara Pistilli, Joana Mourato-Ribeiro, Cyril Roussel-Simonin

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