Pediatric Cancer Models

• 6165 · PDF Matrix density shapes early invasion and EWSR1::FLI1 protein dynamics in Ewing sarcoma Manon Watzky, James Amatruda
• 6166 · PDF Next-generation models to advance pediatric solid cancer treatments Emon Nasajpour, Dena Panovska, Ruolun Wei, Conrado Soria, Calvin J. Kuo, Rachana Agarwal
• 6167 · PDF Modeling the impact of chemotherapy and small molecule inhibitors on the 3D microenvironment of pediatric bone sarcomas Allison Haley Reno, Joshua Kelley, Reid Barker, Jamie Silverman, Jack Hyland, Cameron Bumbleburg, Elizabeth Maahs, Anna Tingler, Denis C. Guttridge, Melinda A. Engevik, Yongren Wu, Casey Langdon
• 6168 · PDF Investigating the mechanism of oncogenesis of BCOR-CCNB3 fusion positive sarcomas Victoria Ann Pete, Ryota Shirai, Sydney Hakim, Joshua Broadman, Naoki Oike, Andrew E. Goodspeed, Masanori Hayashi
• 6169 · PDF Evaluating TCR mimetic CAR T cell preclinical therapeutics in an immunocompetent MYCN-driven murine neuroblastoma allograft model Elisabeth Posthill, Minu Samanta, David Groff, Colleen Casey, Tina Acholla, Anna Maria Giudice, Kristopher R. Bosse, Ruoning Wang, Timothy T. Spear, John M. Maris
• 6170 Development and characterization of 3D osteosarcoma models recapitulating tumor heterogeneity and bone microenvironment Margaux Chantoiseau, Pierre Khneisser, Birgit Geoerger, Nathalie Gaspar, Maria Eugénia Marques da Costa, Antonin Marchais
• 6171 · PDF Patient-derived pediatric glioblastoma models provide key insights into IDH1-driven drug resistance Stephen Friend, Matthew Graziano, Ruby E. Thamert, Heather Branscome, Utsav Sharma, Abhay Andar, Carolina Lucchesi
• 6172 · PDF The transcription factor DMRTA2 regulates radial glial maintenance and tumorigenicity of pediatric high-grade glioma Hitomi N. Royston, Autumn B. Hampton, Elissa G. Oliver, Jayden Jackson, Ibukunoluwa Florence Tella, Miriam D. Emerson, Dhruv Bhagat, Daijiro Konno, Kosuke Funato
• 6173 · PDF Developing zebrafish avatars for pediatric sarcomas to support functional precision oncology Karoline Felisbino, Jonathan Tyler Kinder, Colin Williams, Andrew Gaines, Jessica Blackburn
• 6175 · PDF Development of a human neuroblastoma organoid model Simon Tusnady, Eva Bakos, Anna Lovrics, Katalin Monostory, Jozsef Tovari, Andras Furedi, Kornelia Szebenyi
• 6176 · PDF Embryonic reprogramming of neural crest cells drives the development of Ewing sarcoma Elena Vasileva, Claire Arata, Yongfeng Luo, Gage Crump, James Amatruda
• 6177 · PDF Targeted posterior fossa A ependymoma therapy using a tumor-selective nanoparticle drug delivery approach Jon D. Larson, Darren Finlay, Yan Yuen Lo, Rabi Murad, Ming Zhao, Antony MichaelRaj, Sachin A. Kumar, Kristen Vogt, Ian Pass, Charles Handley, Bryan K. Li, Robert J. Wechsler-Reya, Michael D. Taylor, Kristiina Vuori, Michael Jackson, Daniel A. Heller, G. Praveen Raju, Lukas Chavez
• 6178 · PDF Establishment and analysis of spontaneous metastatic PDX models of Ewing sarcoma Ali Mokhtar Mahmoud, Unsun Lee, Arnulfo Mendoza, Christine M. Heske
• 6179 · PDF Differential sensitivity of paired FUS-TFCP2+ RMS PDX models developed from tumor specimens obtained prior to and after ALK inhibitor therapy Erika Dobrota, M. Reza Saadatzadeh, Barbara Bailey, Keiko Kreklau, Gabe Mervis, Kathy Coy, Felicia Kennedy, Melissa Trowbridge, Anthony Sinn, Christopher Davis, Steven Angus, Michael Ferguson, Pankita Pandya, Karen Pollok
• 6180 · PDF Gene editing in the mouse reveals functional mechanisms of ASPS-TFE3 induced translocation renal cell carcinoma Gopinath Prakasam, Alana Christie, Lisa Kinch, Jeffrey Miyata, Quyen Do, Mylinh Nguyen, Robert Hammer, Payal Kapur, James Brugarolas
• 6181 · PDF Development of a clinically relevant in vitro model of ETMR and implications for drug efficacy studies Evangelos Liapis, Adele Ponzoni, Lea Anne T. Maristela, Claire L. Carter, Derek Hanson
• 6182 · PDF Post-transcriptional silencing of p14ARF drives retinoblastoma malignant conversion in CRISPR-engineered retinal organoids Jinlun Bai, David S. Koos, Kevin Stachelek, Bhavana Bhat, Susan Asatrian, Patrick Belen, Sunjum Sanghari, Kayla Stepanian, Scott Fraser, Rex A. Moats, David Cobrinik
• 6183 · PDF MIAC51 cells induce rapid-onset leukemia across multiple rat strains: A novel and reproducible model of Chloroleukemia Joel Costoya, Joaquin J. Jimenez
• 6184 · PDF Site-specific tumor modeling: DIPG and meningioma in mice Melissa Tran, Cheryl Davis, Ben Hoerner, Victoria Caruso, Helen Ketteringham, Corrine Silvio, Shannan Paul, Chris Holding, Aliccia Koznecki, Dawn Lusk, Shorena Nadaraia-Hoke, Delaney McCormick, Jocelyn Saurbaugh

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