Fibroblasts as Architects of the Tumor Microenvironment

• 6024 · PDF Decoding new mechanisms of stromal-driven inflammation in breast cancer Fernanda G. Kugeratski, Lisa Neilson, Adrian Kacperczyk-Perdyan, Juan R. Hernandez-Fernaud, Sergio Lilla, Jakub Mieczkowski, Sara Zanivan
• 6025 · PDF Transgelin-positive cancer-associated fibroblasts promote pancreatic cancer progression Keiko Shinjo, Xingxing Wang, Kohei Kumegawa, Reo Maruyama, Shinji Mii, Yukihiro Shiraki, TATSUNORI NISHIMURA, Yoshiteru Murofushi, Miho Suzuki, Atsushi Enomoto, Yutaka Kondo
• 6026 · PDF Iron metabolism underlies the activation of cancer associated fibroblasts Kedi Huang, Minh Duc Pham, Chang-il Hwang
• 6027 Cancer associated fibroblasts-derived PDE3A promotes lipid raft-regulated IGF-1R translocation and immunotherapy resistance in triple negative breast cancer Na Hao
• 6028 · PDF The impact of CAF-derived ANKRD1 on the lung cancer tumor microenvironment Kazuhiro Okada, Ken Suzawa, Shunsuke Mori, Kenta Manabe, Ryunosuke Fujii, Kousei Ishimura, Ryota Fujiwara, Kazuya Hisamatsu, Ryo Yoshichika, Atsushi Matsuoka, Yuma Fukumoto, Hidejiro Torigoe, Kazuhiko Shien, Shinichi Toyooka
• 6029 SFRP4+ cancer-associated fibroblasts drive IL-6/STAT3-mediated EMT and immunosuppressive tumor microenvironment in hepatocellular carcinoma Hyo Jung Cho, Sujin Kim, Hye Ri Ahn, Minsu Kwon, Myungchan Park, Tae Jun Park
• 6030 · PDF Gli2 increases Osteopontin expression to alter cancer associated fibroblast behavior Zenaida Fuentes, Rachel Mangano, Jade Miller, Erik Beadle, Julie Rhoades
• 6031 · PDF The Treg-fibroblast axis shapes the immunosuppressive tumor microenvironment in colorectal cancer Liqian Ma, Mingying Bi, Bonnie Huang, Lilian Ho, Hin Ching Lo, Min Liao, Gaurav Mehta, Nicole Belmar, Michelle Chen, Tifani Anton, Areej Ammar, Haiyan Li, Kyle Halliwill, Kate MacDonald
• 6032 Subtypes of cancer-associated fibroblasts, myCAF, iCAF, and apCAF, might be associated with adverse prognostic signature of patients with gastric cancer DONGHENG MA, Hinano Nishikubo, Tomoya Sano, Daiki Imanishi, Takashi Sakuma, Canfeng Fan, Yurie Yamamoto, Masakazu Yashiro
• 6033 Different roles of cancer-associated fibroblasts in pancreatic cancer and biliary tract cancers cancer-associated fibroblasts as a tumor suppressor in biliary tract cancers Ryota Tanaka, Kenjiro Kimura, Naoki Tani, Shimpei Eguchi, Daisuke Inoue, Takuto Yasuda, Changgi Ahn, Koichi Nakanishi, Kosuke Hatta, Shigeaki Kurihara, Jun Tauchi, Sadaaki Nishimura, Masahiko Kinoshita, Kohei Nishio, Hiroji Shinkawa, Takeaki Ishizawa
• 6035 · PDF Non-immune stromal reprogramming shapes breast cancer immunotherapy resistance: insights from mouse models Yujia Yue, Stephanie Mittman, Rohit Reja, Julia Lau, Minyi Shi, Ana Xavier-Magalhaes, Jonathan Paw, Carolina De Amat Herbozo, Marco De Simone, Yan Qu
• 6036 Antigen-presenting cancer-associated fibroblasts in murine pancreatic tumors differentially control regulatory T cell phenotype and function via CCL22 Saumya Maru, Meredith Wetzel, Jacob Mitchell, Nicole Gross, Lalitya Andaloori, Kathryn Howe, Emma Kartalia, Guanglan Mo, James Leatherman, Won Jin Ho, Elana Judith Fertig, Luciane Tsukamoto Kagohara, Edward J. Pearce, Elizabeth M. Jaffee
• 6037 · PDF An immune-activating and tumor-suppressive subtype of cancer-associated fibroblasts identified in gastric cancer HUAITAO WANG, Takashi Semba, Atsuko Yonemura, Takatsugu Ishimoto
• 6038 · PDF Cancer associated fibroblast subtype heterogeneity in colorectal cancer influences primary tumor invasion Bethany Haliday, Carly Strelez, Eileen Fung, Shannon M. Mumenthaler
• 6039 · PDF Cancer cell-driven HIF-1alpha activation enhances the motility of cancer-associated fibroblasts in the lung tumor microenvironment Jihye Park, Sieun Lee, Jonathan M. Kurie, Young-Ho Ahn
• 6040 Targeting EP3⁺FAP⁺ stromal reprogramming uncovers a therapeutic vulnerability in early recurrent hepatocellular carcinoma guiqi zhu, guan zhiqi, yinghong shi, weiren liu, zheng tang, Kang Wang, jia fan
• 6041 · PDF Fidaxomicin targets PDGFR⁺ cancer-associated fibroblast to restrain colorectal cancer progression Haoxiang Zhang, Xudong Zhu, Chang Li, Yinping Jiang, Yuning Zhou, B. Mark Evers, Qingding Wang
• 6042 · PDF Targeting GABA signaling in cancer associated fibroblasts to reduce immunosuppression in pancreatic cancer Ariana Musa de Aquino, Myree Graves, Kyra Langley, Peter Sajjakulnukit, Ian Loveless, Nina Steele, Julie Clark, Alexander Muir, Costas Andreas Lyssiotis, Ralph Francescone, Débora B. Vendramini-Costa, Guilaume Cognet G, David Kwon
• 6043 · PDF Deactivating liver metastatic colorectal cancer-associated fibroblasts with all-trans retinoic acid Brandon Choi, Ken Huang, Yuyuan Zhou, Seungil Kim, Eileen Fung, Shannon M. Mumenthaler
• 6044 · PDF Immunosuppressive role of DKK1 and cancer-associated fibroblasts across molecular subtypes of endometrial cancer Alessandro Canella, Danielle Glassman, Keith Brownewell, Caprice Eisele, Aharon Gideon Freud, Casey Cosgrove
• 6045 Exploring surface interactors promoting viability of CLL cells in contact with stromal fibroblasts Uday Aditya Sarkar, Domenico Maisano, Stacey M. Fernandes, Kiyomi Mashima, Colin Mcnulty, Nikhil C. Munshi, Jennifer R. Brown, Fabiana Perna, Eugenio Morelli, Paolo P. Ghia
• 6046 · PDF Spatial transcriptomic profiling of cancer-associated fibroblast niches in extrahepatic cholangiocarcinoma Giulia Petroni, Simone Romagnoli, Daniele Lavacchi, Giulia Massaro, Francesca Rizzo, Elena Alexandrova, Costanza Winchler, Alfonso Carleo, Gian Luca Grazi, Daniele Rossini, Luca Messerini, Matteo Benelli, Serena Pillozzi, Lorenzo Antonuzzo
• 6047 · PDF CTHRC1-TGFb crosstalk between myofibroblasts and tumors drives invasion in early-stage lung adenocarcinoma Abhilasha Sinha, SEUNGYEUL YOO, Nanzeeba Faraby, Thinh Nguyen, Hideo Watanabe, Alexander Tsankov, Jun Zhu, Charles A. Powell
• 6048 · PDF CAF-secreted periostin promotes tumor aggressiveness in BRAF - mutant papillary thyroid carcinoma by upregulating MMP1 ZHUORAN LIU, JINYUE LIU, JIE KUANG, WEIHUA QIU
• 6049 Cartilage oligomeric matrix protein, cancer-associated fibroblast phenotypes, and versican proteolysis modulate CD8+ T cell infiltration in colorectal cancer Cadence E. Brown, Ruchi Shah, Cindy Wuerz, Isoline M. Donohue, Katherine A. Johnson, Cheri Pasch, Dustin A. Deming
• 6051 Pancreatic tumor expressed growth factors activate a neural-like program in human fibroblasts which is associated with poor prognosis Myriam Iliana Ibanez Rios, Maëlle Batardiere, Alexandre Archambault-Marsan, Elham Dianati Ajibisheh, Vincent Quoc-Huy Trinh, David J.H F. Knapp

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