Liquid Biopsies: Circulating Nucleic Acids 5

• 7820 · PDF CHIP detection in solid tumors differs between liquid biopsy testing approaches Florian Klemm, Fuad Mohammad, Alex Charles Tuck, Grecia Morales, Rochelle Awuku, Katya Mokretar, Alasdair Heasman, Gareth Gerrard, Persephone du Parcq, Zhenyu Xu
• 7821 · PDF Plasma-based comprehensive epigenomic profiling enables multiplexed prediction of target gene expression and detection of resistance mechanisms Nicole Kramer, Jonathan Beagan, Aparna Gorthi, Praful K. Ravi, Rashad Nawfal, Anthony D'Ippolito, Sylvan C. Baca, Travis A. Clark, Khoi Nguyen, Daniel Karl, Kristian Cibulskis, Karl Semaan, Marc Eid, Jacob E. Berchuck, Corrie A. Painter, Matthew L. Eaton, J. Carl Barrett
• 7822 · PDF High-sensitivity cfDNA detection of KRAS amplification subtypes to inform targeted therapy response and resistance mechanisms Yong Huang, Lisha Zhu, Binggang Xiang, Pan Du
• 7823 · PDF Ultrasensitive abnormal DNA methylation detection in plasma samples from patients with three different childhood sarcomas Giancarlo Bonora, Ziqi Zhu, Binggang Xiang, Kemin Zhou, Pan Du, Soumya Turaga, Glenson Samuel, Andrew Godwin
• 7824 Plasma-only classification of CHIP, low-VAF germline, and somatic variants enables accurate tumor-fraction estimation without matched normal samples Tiantian Zheng, Yong Huang, Chao Dai, Junmei Wang, Xiaohong Wang, Pan Du
• 7825 Ultra-sensitive MRD detection through comprehensive structural variant profiling in solid and hematologic malignancies Kemin Zhou, Yong Huang, Abby He, Junmei Wang, Binggang Xiang, Xiaohong Wang, Pan Du
• 7826 · PDF Monitoring molecular residual disease in colorectal cancer using tumor-informed ctDNA analysis William C. Cho, Qianqian Yao, Yingyu Wang, Tam Berntsen, George Yeung, Paul Tang, Tobias Wittkop, Li Weng, Lui Ng, Dominic C.C. Foo
• 7827 · PDF Analytical evaluation of tumor-naive ctDNA molecular response detection through baseline informed comprehensive genomic profiling with matched white blood cell analyses Cynthia Maddox, Cesar Nalvarte, Amanda Harvey, Vito Caropreso, Andrew Georgiadis, Aanavi Karandikar, Kenneth C. Valkenburg, Eric Severson, Taylor J. Jenson, Shakti Ramkissoon, Mark Sausen
• 7828 · PDF Development of a comprehensive tumor-informed ctDNA workflow for ultrasensitive molecular residual disease detection using diverse tumor profiling inputs Leisa Jackson, Helen Halpin, Emma Longshore, Gary A. Pestano
• 7829 · PDF Fragmented plasma cfDNA as a prognostic and surveillance biomarker for locoregional recurrence in oral squamous cell carcinoma Jiyoung Lee, Mi Rim Lee, Sumin Kang, Jung-Ah Hwang, Hye Won Shon, Yu-Sun Lee, Sun Il Choi, Gyeongmin Kang, Jong-Ho Lee, Sun-Young Kong, Sung Weon Choi, Yun-Hee Kim
• 7830 · PDF Transport under various conditions: Evaluating blood sample stability across seasons Daniel Grölz, Markus Wolf, Daniela Mancarella-Langer, Franziska Kaiser, Michelle Walther, Eric Provencer
• 7831 · PDF Diagnostic genomics in retinoblastoma: Aqueous humor outperforms blood for tumor-specific insights Elaine Huang, Atrey Khoche, Sabrina Abed, Venkata Yellapantula, Laura Kagami, Brianne Brown, Liya Xu, Jesse L. Berry
• 7832 · PDF Plasma epigenomic profiling captures B-cell lymphoma biology Aleem Aamir, Steven De Michino, Michael Hong, Ting Liu, Victoria Shelton, Benjamin Haibe-Kains, Michael M. Hoffman, Mathieu Lupien, Robert Kridel, Benjamin Lok, Scott V. Bratman
• 7833 · PDF A novel extraction method for enrichment of circulating cell-free DNA Seka Lazare, Megan Rivera, Zachary Costliow, Ashley Tellis, Zhuosheng Gu, Michael A. Harmon, Wendy Winckler
• 7834 DNA methylation: A highly accurate biomarker for treatment monitoring - A retrospective case study using cfDNA methylation and machine learning in breast cancer patients Jean-Valery Turatsinze, Andrea Blum, Adrien Godfroid, Ekaterina Gracheva, Matteo Tosolini
• 7835 · PDF Integrated DNA/RNA recovery from 1-20 mL inputs enables sensitive KRAS G12V detection in a liquid biopsy model Mayer Saidian, Jason Saenz, Carlos Hernandez, Cameron Van Dieren, Daniel Cedeno, Nafiseh Jafari
• 7836 · PDF Automated high-volume cfDNA extraction on a liquid-handling platform achieves analytical equivalence to a manual high-input magnetic-bead workflow with 96-sample throughput Nafiseh Jafari, Cameron Van Dieren, Jason Saenz, Carlos Hernandez, Daniel Cedeno, Mayer Saidian
• 7837 · PDF Enhanced sensitivity and scalability in liquid biopsy through integrated high-volume cfDNA extraction and droplet digital PCR mutation detection Nafiseh Jafari, Andrew Partner, Necip Mehmet, Nish Kumar, Prithwish Pal, Jason Saenz, Carlos Hernandez, Daniel Cedeno, Cameron Van Dieren, Mayer Saidian
• 7838 · PDF Innovative biomarker discovery: A non-invasive, comprehensive tumor characterization approach with plasma and urine from breast cancer patients Ivonne Nel, Ekaterina Firsova, Laura Weydandt, Bahriye Aktas
• 7839 · PDF EU Instand-NGS4P: Pre-analytical multimodal workflows for NGS research and future precision cancer care Franziska Kaiser, Daniela Mancarella-Langer, Daniel Groelz, Jörg Lindenmann, Iurii Mykoliuk, Paul Swatek, Peter Michael Abuja, Kurt Zatloukal, Kalle Guenther, Uwe Oelmueller
• 7840 · PDF Evaluation of somatic mutations in cell-free DNA as noninvasive biomarkers of cancer in asymptomatic pregnant women Zhigang Kang, Amy E. Turriff, Yuelin Jack Zhu, Erica Pehrsson, Hsein-Chao Chou, Jun Wei, Kerstin Heselmeyer-Haddad, Paul S. Meltzer, Javed Khan, Liang Cao, Diana W. Bianchi
• 7841 · PDF Evaluation of uProcess for detection of oncogene sequences in buffer and urine by qPCR following 3-minute capture and 5- minute purification procedure Floyd E. Taub, Sean Pearson, Suzin E. M. Wright, Charles (Preston) Neff
• 7842 · PDF A new high fidelity PCR master mix with broad NGS workflow compatibility and superior performance in high sensitivity applications Margaret R. Heider, Kyle Vrtis, Jian Sun, Bradley W. Langhorst, Chen Song, Yan Wang, Nicole M. Nichols
• 7843 · PDF Integrated multiomics for deep molecular exploration of prostate cancer from urine Bhaven Mehta, Andrea O’Hara, Ethan Stancliffe, Tom Cohen, David Corney, Haythem Latif
• 7844 · PDF Simultaneous identification of methylation and somatic variants can improve sensitivity for cancer detection and monitoring Tom Charlesworth, Cillian Nolan, Luke Sarre, Fabio Puddu, Angela Simeone, Aurelie Modat, Ermira Lleshi, Robert Crawford, Robert J. Osborne, Thao Huynh
• 7845 · PDF Dynamic plasma KRAS and EGFR ctDNA profiling identifies treatment response and nascent resistance in metastatic lung cancer Valentina Buzzi, Greta Berti, Michele Santillo, Arianna Belli, Giulia Favarato, Mauro Iannopollo, Elisabetta Rosi, Federico Lavorini, Sara Tomassetti, Annarosa Arcangeli, Elena Lastraioli

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