Role of the Microenvironment in Therapeutic Response

• 7169 Longitudinal single-cell profiling of breast tumors reveals immune and epigenetic mechanisms of sensitivity and resistance to aromatase inhibitors Ilayda Altinönder, Villads Winton, Quy Khang Le, Marie Fongaard, Paal M. Bjornstad, Elin Edda Seland Agustsdottir, Stephanie Geisler, Kamilla Fjermeros, Manouchehr Seyedzadeh, Unn-Cathrin Buvarp, Marianne Lyngra, Arnoldo Frigessi, Diether Lambrechts, Vessela N. Kristensen, Anthony Mathelier, Victor Greiff, Jürgen Geisler, Xavier Tekpli
• 7170 AKT inhibition with capivasertib counteracts tumor microenvironment remodeling and enhances AR-targeted therapy in PTEN-deficient prostate cancer Marco A. De Velasco, Kazuko Sakai, Daiki Nakatsu, Mamoru Hashimoto, Saizo Fujimoto, Shingo Toyoda, Takafumi Minami, Kazuhiro Yoshimura, Simon T. Barry, Cath Eberlein, Claire Rooney, Kazuto Nishio, Hirotsugu Uemura, Kazutoshi Fujita
• 7171 · PDF Antitumor and antiangiogenic activities of E7386 in combination with lenvatinib in human endometrial carcinoma xenograft models Yusuke Adachi, Yudai Narita, Shogo Yamaguchi, Taro Semba
• 7172 Combination of B7-H4-TOP1i ADC, PD-1/TIGIT bispecific antibody, and PARP inhibition orchestrates angiogenesis suppression and interferon-program activation in a syngeneic mouse model Octavio Morante-Palacios, Jon Chesebrough, Yoshimi Johnson, Raymond Rothstein, Varsha Shankarappa, Joseph Boland, Elizabeth Galery, Anna Dominika Staniszewska, Mark R. Albertella, Alex Cazes, Paul Chariou, Bilal Omar
• 7173 · PDF Mechanistic studies of fibroblast activation protein activated prodrug AVA6000 in pancreatic and liposarcoma models Lisa Pickard, Ekta Paranjape, Brian Cunningham, Udai Banerji
• 7174 · PDF Restoring antitumor immunity and improving immunotherapy outcomes in KRAS-mutant NSCLC through MYC inhibition by OMO-103 Íñigo González-Larreategui, Sílvia Casacuberta-Serra, Magda Arnal, Daniel Capitán-Leo, Sandra Martínez-Martín, Vera Adradas, Melina Peressini, Laura Vera, Lorena Sansegundo-Barbosa, Fabio Giuntini, Manuel Lillo-Valero, Manrique Valdés-Bango Martín, Erika Serrano del Pozo, Judit Grueso, Laia Foradada, Sergio López-Estévez, Hugo Thabussot, Jonathan R. Whitfield, Marie-Eve Beaulieu, Jon Zugazagoitia, Silvestre Vicent, Laura Soucek
• 7175 · PDF Targeting spatial patterns of CAFs and tumor cells for precision stroma-targeted radionuclide therapy Yuning Sun, Ye Yang, Guanyu Zhu, Jiangang Zhang, Xiaowei Fan, Jian Wang, Yang Liu, Shaoyan Liu, Yansong Lin, Xi-Yang Cui, Zhibo Liu, Ziren Kong
• 7176 · PDF Next-generation human vascularized tumor models reveal HER2-independent efficacy and reduced vascular toxicity of T-DXd Francesco Bonollo, Soheila Zeinali, Sabine Schneider, Christian Moser, Olivier Thierry Guenat
• 7178 · PDF Targeted modulation of the blood-tumor barrier enhances drug delivery and survival in glioblastoma models Philippa C. Vaughn-Beaucaire, William Hawkins, Jasmine S. Clark, Jorge Luis Jimenez Macias, Bin Wu

在完整检索应用中浏览本分会场 →