Tumor-induced Immune Suppression

• 6989 · PDF RBM10 loss promotes KRAS -mutant non-small cell lung cancer immune tolerance and PD-1 inhibitor resistance via a non-canonical STING/ NF-κB axis Minh Truong Do, Teng Zhou, Mhd Yousuf Yassouf, Richard Lee, Obada E. Ababneh, Yanhua Tian, Leticia B. Rodriguez, Jayanthi Gudikote, Haniel A. Araujo, Stephanie T. Schmidt, Jing Wang, Frank R. Rojas Alvarez, Luisa M. Solis Soto, Marcelo V. Negrao, Alexandre Reuben, Don L. Gibbons, Jianjun Zhang, John V. Heymach, Ferdinandos Skoulidis
• 6990 Identification of a secretory immune regulatory ligand Benjamin Nicholson, Sydney Fisher, Matthew Wren, Weijie Guo, Yuxuan Phoenix Miao
• 6991 · PDF Direct adhesion of activated platelets suppresses anti-tumor activity of CTL through CD62p-PSGL1 binding Sae Nishiguchi, Masaru Yokomura, Yuki Gomibuchi, Seiji Nagano, Takuo Yasunaga, Hiroshi Kawamoto, Satoshi Takagi, Ryohei Katayama
• 6992 Tumor stem cells reprogram neutrophils to establish a protective niche Weijie Guo, Jingyun Luan, Yuxuan Phoenix Miao
• 6993 · PDF Targeting PDE4A ablates an immune checkpoint and unleashes STING-Driven anti-tumor immunity Yuting Bai, Kejia Xu, Huimin Liu, Haojie Chen, Yi Shi, Rong Xiang
• 6994 · PDF Proline metabolic competition drives CD8⁺ T cell ferroptosis in BRAF-mutated thyroid cancer Yuanxing Dong, Xinyue Liu, Xiangqian Zheng
• 6995 · PDF Spatial immune landscape in metastatic colorectal cancer Susrutha Puthanmadhom Narayanan, Chien-Wei Peng, Adrienne Visani, Xiangwei Fang, Andre Luiz N. Targino da Costa, Jingxian Liu, Reyka G. Jayasinghe, Ambrose Plante, John M. Herndon, Jacqueline Mudd, Preet Lal, Wagma Caravan, Kapur B. Dhami, Jennifer Ponce, Robert S. Fulton, Michael Heinz, Milan G. Chheda, Feng Chen, Michael Iglesia, Ryan C. Fields, Li Ding
• 6996 · PDF Immune regulatory functions and therapeutic opportunities of MIF signaling in pancreatic cancer Blake Schwettmann, Fei Peng, Angad Kumar, Valli Annamali, Jason Toombs, Rolf Brekken, Ravikanth Maddipati
• 6997 · PDF Defining mechanisms limiting NK cell function in the multiple myeloma tumor microenvironment Sadia Afrin, Michelle Becker-Hapak, Lyra Morina, Wilbur Song, Jennifer A. Foltz, Alice Zhou, Kunal Shetty, Yeeun Paik, Samuel Ameh, Emily Philips, Timothy Schappe, Mark Foster, Lynne Marsala, Sushanth Pureti, Yoo-Jin Ahn, David Russler Germain, Todd A. Fehniger
• 6998 · PDF Use of non-steroidal anti-inflammatory drugs, acetaminophen and somatic immune profiles in breast tumors Clara Bodelon, James Hodge, Daniel G. Stover, Melissa A. Troester, Lauren E. McCullough, Alpa V. Patel, Lauren R. Teras
• 6999 · PDF GDF-15 inhibition overcomes treatment resistance to platinum- and taxane-based cytotoxic chemoimmunotherapy Neha Vashist, Amelie Köhler, Daniel Schätzlein, Sabrina Genßler, Katja Rungger, Hubert Hackl, Matthias Kist, Sarah Lutzenberger, Julia Weigandt, José Medina-Echerverz, Christine Schuberth-Wagner, Thorsten Ross
• 7000 · PDF Genome-wide CRISPR screening reveals tumor-intrinsic immune evasion mechanism in ovarian cancer Junyong Park, Jiho Lee, Hyun Ju Kang, Jin-Ku Lee
• 7001 · PDF Tumor-intrinsic suppression of phagocytosis by RRP1 (ribosomal RNA processing 1) in glioblastoma Eshika Kudaravalli, Amr Elkholy, Mostafa Mohamed, Hasan Alrefai, Saeed Zakakhosravi, Satoru Osuka, Christopher D. Willey, Erin Ahn
• 7002 · PDF Immune evasive characteristics of the KRAS mutant colorectal cancer tumor microenvironment Elizabeth A. Boeree, Katherine A. Johnson, Cheri A. Pasch, Dustin A. Deming
• 7003 · PDF The RKIP-HER2 axis regulates breast cancer immune evasion Ania Khachikian, Mai Ho, Benjamin Bonavida
• 7005 · PDF Tumor cell CEBPB expression contributes to T cell-mediated immune evasion of microsatellite stable colorectal cancer Hye Jeong Yun, Chan Ho Park, Dahye Yun, Hye-Ri Shin, Naeun Park, Changhee Park, Jeong Dong Lee, Kiyeon Kim, Heejun Shim, Hyejin Sim, Se Min Kim, Min Jung Kim, Ji Won Park, Seung-Bum Ryoo, Yoojoo Lim, Seung-Yong Jeong, Kyu Joo Park, Tae-You Kim, Junil Kim, Jae-Kyung Won, Sae-Won Han
• 7006 · PDF Inhibiting intracellular cPLA2alpha in cervical cancer cells enhances antitumor immunity and facilitates the efficacy of anti-PD1 checkpoint immunotherapy Yuchao He, Xiangdong Tian, Liwei Chen, Yi Luo, Yu Wang, Lu Chen, Hua Guo
• 7007 · PDF Hypoxia-mediated suppression and memory of IFI44L and its interaction with STING in breast cancer metastasis and immune evasion Rebecca Marker, Aidan Moriarty, Remi Klotz, Min Yu
• 7008 Multi-omic analysis nominates SPP1-IL10 axis as a novel immunotherapeutic target in gastric peritoneal carcinomatosis Turcios Lilia, Neelima Hosamani, Ellen Beswick, Joseph Kim, Mautin Barry-Hundeyin
• 7009 · PDF From correlation to causation: SOX11 drives a coordinated immune-suppressive network that represses antigen presentation in triple-negative breast cancer Salomat Abdulkhuseynova, Ashok Pullikuth, Lance D. Miller
• 7010 · PDF Trogocytosis-orchestrated CLDN18.2-dressed CD8 + T cells drive pancreatic cancer progression via glucose metabolic reprogramming-induced cytotoxicity debilitation and systematic immune senescence-cascade Jingrui Yan, Tianxing Zhou, Jun Yu, Jihui Hao
• 7011 · PDF ROCK2-regulated LIF-STAT3 drives immunosuppression in pancreatic cancer Varunkumar Krishnamoorthy, Sudhakar Jinka, Siddharth Mehra, Phuong Hong Ngoc Tao, Daysi Daniela Manrique, Rimpi Khurana, Yuguang Ban, Vineet Kumar Gupta, Austin Dosch, Nagaraj Nagathihalli
• 7012 · PDF Single-cell multi-omics identifies MRD-associated Tr1-like CD4 cells in B-ALL Qianyun Luo, Rebecca LaRue, Enoc Granados Centeno, Kyra Bergerud, Michael Farrar, Sean Tracy
• 7014 · PDF SPIN1 drives PD-1 immunotherapy resistance in gastric cancer by inducing M2 macrophage polarization and suppressing CD8⁺ T-cell immunity Beibei Lyu, Zijun Yidan Xu-Monette, Xiaoyan lin
• 7015 · PDF USP5 suppresses MRE11 endonuclease function to facilitate tumor immune escape Chuan-Chun Lee, Wan-Rong Wu, Liang-Chih Liu, Ting-Yi Liao, You-Zhe Lin, Fang-Ying Lin, Yi-Chun Shen, Yuan-Liang Wang, Chih-Hao Lu, Wei-Chung Cheng, Wei-Chao Chang, Yi-Chuan Li, Chih-Tung Lin, Chung-Yu Chen, Sheng-Wen Chen, Hsin-An Shih, Steven Lin, Chen-Yuan Lin, Chang-Fang Chiu, Shao-Chun Wang
• 7016 · PDF Targeting sialylation promotes anti-tumor immunity in small cell lung cancer Alex D. Doan, Kelly Heard, Jackson Fatherree, Mallika Yalangi, Pritha Chanana, Mitchell Kluesner, Daniel S. Hippe, Cody Jenkins, Hannah Kerbyson, Shivani Srivastava, David MacPherson
• 7017 · PDF EMP2 is a potential immunotherapeutic target to modulate macrophage-induced phagocytosis in glioblastoma Amr Elkholy, Eshika Kudaravalli, Mostafa Mohamed, Hasan Alrefai, Saeed Zakakhosravi, Satoru Osuka, Christopher D. Willey, Ahn Erin
• 7018 · PDF The CBS-CXCL10 signaling axis supports tumor progression by driving immune suppression within the tumor microenvironment Fanghui Chen, Fan Yang, Jianqiang Yang, Nabil Saba, Yong Teng

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