Targeting Mitochondria and Metabolic Vulnerabilities for Cancer Therapy

• 549 BTM-3566 activation of the mitochondrial protease OMA1 increases sensitivity to venetoclax and azacitidine in acute myelogenous leukemia. Matthew Kostura, Michael Luther, Todd Hembrough, Glen J. Weiss, Michael T. Stocum
• 550 Targeting heat shock factor 1 in pancreatic ductal adenocarcinoma autophagy and iron-sulfur cluster protein stability Rejina Shrestha, Shruti Ghai, Hannah Nam, Kuo-Hui Su
• 551 · PDF Advancing cancer treatment through targeting dipeptidyl peptidase 8 an innovative strategy for overcoming resistance Paras Jawaid, Mati Ur Rehman, Azhar Hussain Rajabali, Ather Enam
• 552 · PDF Functional effects of miPEP133 on mitochondrial integrity and treatment response in ovarian cancer Samantha Goncalves Novo, Miranda Mansolf, Tobias M. Hartwich, Jasmine Jathan, Viktoriia Kolesnyk, Yang Yang-Hartwich
• 553 · PDF Selective induction of cuproptosis in vivo by a soluble Elesclomol analog Piyush Mishra, Mainak Banerjee, Jian-Ren Lin, Shannon Coy, Jeffrey Hsiao, Jonah Lee, John Clohessey, Alexandre Detappe, Todd R. Golub, Loic Charbonniere, Sandro Santagata, Peter Tsvetkov
• 554 Asbestos exposure induces carcinogenesis via minority MOMP and displays characteristics of drug-tolerant persister cells Jaylon C. Aggison, Cristian G. Medina, Siqi Wu, Naren Li, Francisco A. Molina-Pelayo, Jessica B. Ji, Ritika Raj, Yuan Xu, Robert Taylor Ripley
• 555 Prostaglandin E2 increases lipid droplet accumulation and peri-droplet mitochondria population in acute lymphoblastic leukemia Byourak Shabane, Cristiane Beninca, Michael Cohen, Nikole Scillitani, Ugochukwu Ihenacho, Orian Shirihai, Steven D. Mittelman
• 556 · PDF Inhibition of mitochondrial protein MAGMAS increases sensitivity to standard of care treatment Javier J. Lepe, Shashi Jain, Naomi Lomeli, Claire Chen, Bhaskar C. Das, Daniela A. Bota
• 557 · PDF TRAP1 represents a mitochondrial target and biomarker of dedifferentiated liposarcoma Roma Karna, Esin Ulker, Sydney Rentsch, Marina Capece, Sayumi Tahara, Qi Zhang, Patricia Sarchet, Giovanni Nigita, Paolo Fadda, Fernanda Costas Casal de Faria, Valerie Grignol, Nicholas C. Denko, Carlo M. Croce, Raphael E. Pollock, Federica Calore
• 558 Benzyl isothiocyanate induced mitochondrial dysfunction via ROS generation sensitizes head and neck squamous cell carcinoma to cisplatin and radiation Imani Aliah Kirven, Francesca Spirito, Patrice Penfornis, Kristin S. Edwards, Gary R. Bishoop, Linda L. Eastham, Chunli Yang, Rojymond Jacob, Pier Paolo Claudio
• 559 · PDF Combination of PRMT5 and Mcl-1 inhibitors overcomes immune checkpoint inhibitor resistance in pleural mesothelioma Siqi Wu, Jaylon Aggison, Cristian Medina, Naren Li, Francisco Molina-Pelayo, Ritika Raj, Yuan Xu, Robert T. Ripley

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