Tumor Cell Plasticity, Microenvironment, and Stress-Response Pathways

• 563 WEE1 reinforces C-MYC driven oncogenic programs through GSK3ß inhibition Krishnapriya Thangaretnam, Islam MD Obaidul, Jialun Lyu, Zhenzhen Zhang, Lei Chen, Farah Ballout, Heng Lu, Dunfa Peng, Alexander I. Zaika, Wael El-Rifai, Zheng Chen
• 564 · PDF Clonal diversity drives cooperative growth in lung cancer Yan Jennifer Gu, Salil Garg
• 565 · PDF Establishing the mechanistic link between chemotherapy response and Hippo-YAP signaling in ovarian cancer Jonathan C. Vose, Elizabeth I. Harper, Sheetal Kooduvalli, Joanne Kotelawala, Ashani Weeraratna, Jennifer M. Kavran
• 566 · PDF UVRAG-ITCH-ESCRT axis mediates a lysosomal off-switch dampening NOTCH1 signaling in cancer Behzad Mansoori, Zihan Zheng, Chintan Parekh, Chengyu Liang
• 567 · PDF SGK1 may represent a therapeutic target in BRAF-mutant melanoma Boyd Griffiths, Camden VanTassell, Joshua Knight, Madison Hawkins, Landen Barnett, Katie Culver, Ashley Thompson-Chadwick, Sheri L. Holmen, Gennie Lynne Parkman
• 568 · PDF The YAP1-IGFBP2 axis as a predictive biomarker and therapeutic target in gastric cancer metastasis Emily Hancin, Hyun-Kyung Ko, Madeline B. Torres, Xiaodan Yao, Yibo Fan, Melissa Pool Pizzi, Shilpa S. Dhar, Francis Spitz, Generosa Grana, Jaffer A. Ajani, Shumei Song
• 569 Acetylcholine-induced YAP stabilization enhances HIF-1 signaling under hypoxia via the nAchR-alpha7/PI3K/PDPK1 pathway in pancreatic cancer cells Yunmi Cho, Ha Hyeong Kim, Eun-Taex Oh
• 570 Soft extracellular matrix orchestrates gastric cancer progression by triggering RNF146-mediated AMOT degradation and YAP/TAZ-driven senescence in macrophages Guofei Deng, Yusheng Luo, Yuxi Pan, Xiaorong Lin, Yuzhi Zhang, Yuqing Lin, Fuhui Wang, Jiancheng Wang, Shuo Fang
• 571 · PDF WNT and Notch crosstalk in pregnancy-associated breast cancer Charles Moore, Wen-Cheng Chung, Shifa Khan, Keli Xu
• 572 · PDF Defining a DLG5-NUAK2-LATS1 complex that regulates Hippo signaling output Youchen Song, Abiodun Ogunjimi, Siyuan Song, Jeffrey L. Wrana, Liliana Attisano
• 573 Cooperative mechanisms driving prostate cancer progression Runhua Liu, Chao Zhang, Haiyan Yui, Lizhong Wang
• 574 · PDF Exploring the therapeutic vulnerability of castration-resistant prostate cancer via Hippo-YAP/TAZ-TEAD signaling Vandana Mohan, Sweaty Koul, Mousa Vatanmakanian, Santosh Lamichhane, Praveen K. Jaiswal, Hari K. Koul
• 575 · PDF Cooperative regulation of YAP activity by STK40 and CDK7 in cancer progression Pei Yi Li, Yi Chin Chen, Feng Chiao Tsai
• 576 Investigating BMP signaling as a therapeutic vulnerability in endometrial cancer Purva Vinayak Gade, Craig Ceol
• 577 · PDF Defects in junctional localization of desmosomal proteins in cancer cells triggered by loss of Septin-9 Cate G. Lyerly, Zach N. Pierce, Adi Dara Dubash
• 578 · PDF Emerging roles of Cyclin F in Non-small lung cell carcinoma during metabolic stress Rohini Tamang, Sanjeev Das, Sangeeta Choudhury
• 580 · PDF TPM4 overexpression modifies differentiated colon epithelial cell barrier integrity Brenna Backus, Michael Papetti
• 581 FUT8-mediated fucosylation promotes colorectal cancer growth and metastatic potential via tumor-fibroblast interactions Zimo Huang, Sree K. Kondapuram, Xiang Y. Zheng, Praveen Agrawal, Chaoyuan Kuang
• 582 Disruption of Cenpj, a centriole biogenesis regulator, diminishes oral cancer susceptibility through p53-dependent DNA-damage repair and apoptosis pathways Mousumi Bhattacharjee, Heena Dave, Rekha Jalandra, Radhika R. Gudi, Chenthamarakshan Vasu
• 583 · PDF Septin-9 binds to Desmoglein-2 and controls cell-cell junction strength in cancer cells Michael W. Jaber, Emily G. Bernier, Adi Dara Dubash
• 584 · PDF Context-dependent roles of sFRP1 in melanoma Cierra Perron, Douglas Quilty, Farzaneh Afzali, Bianca Dauber, Tyler Cooper, Krista M. Vincent, Ivan Topisirovic, Lynne-Marie Postovit
• 585 Effects of bisphenols on gene expression and cellular outcomes in MDA-MB-231 breast cancer cells mediated via G protein-coupled estrogen receptor Norman R. Estes, Cameron Sheeler
• 586 · PDF Pdcd4/mTORC2 axis regulates glycolysis via PFKFB3 in NSCLC Elham Zokaei, Hsin-Sheng Yang, Qing Wang, Yanquan Zhang
• 587 · PDF Choline Acetyltransferase: A novel drug target in lung adenocarcinoma patients who are exposed to tobacco smoke Piyali Dasgupta, Eric W. Bow, Krista Denning, Rama S. Gadepalli, John M. Rimoldi, Yi Charlie Chen, Sarah L. Miles
• 588 Enhancing the efficacy of 5-fluorouracil in targeting thymidylate synthase (TYMS) for breast cancer treatment using honokiol Santosh K. Singh, Rajesh Singh
• 589 Ubiquitin specific peptidase 37 (USP37) facilitate Replication stress tolerance to promote prostate cancer oncogenesis Suraja Kumar Das, Lakshay Malhotra, Gunjan Dagar, Teena Haritwal, Atul Batra, Ajaz A. Bhat, Mayank Singh
• 590 · PDF Role of cellular prion protein in breast cancer through Wnt signaling Parul Dubey, Manoj Kumar Mishra
• 591 · PDF The ubiquitin ligase HUWE1 controls the balance between beta-catenin functions in WNT signaling and cell adhesion Caleb Kwame Sinclear, Joseph McKenna, Yalan Wu, Praveen Sonkusre, Andres M. Lebensohn
• 592 · PDF NSD2 regulates cell growth and oncogenic signaling pathways in laryngeal carcinoma Ahmed Ismail, Iuliia Topchu, Amr Ismail, Tingting Zhang, Xu Jia, Peter Makhov, Yanis Boumber

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