Metabolite Control of Chromatin, Redox, and Cellular Stress Responses

• 535 Acute sleep deprivation reprograms metabolic and mitochondrial pathways linked to cancer risk Behzad Varamini, Harrison Kim, Priscilla Kim, Madeline Lange, Stephanie Zeng, Jennifer Tudor
• 536 A multiplexed LC-MS/MS metabolite assay to enable patient stratification and pharmacodynamic monitoring for MTA-cooperative PRMT5 inhibitors Ethan Stancliffe, Ashima Mehta, Douglas Guzior, Adam Richardson, Tom Cohen, Kevin Cho, Gary Patti
• 537 · PDF Constitutive NRF2 activation drives excess cysteine stress Jennifer A. Brain, Anna-Lena B. G. Vigil, Kristian Davidsen, Ayaha Itokawa, Abby C. Jurasin, Hannah J. Kerbyson, Maximilian Kobiesa, Madeleine L. Hart, Sang Jun Yoon, Gina M. DeNicola, Lucas B. Sullivan
• 539 · PDF Cholesterol triggers chromatin stress to drive senescence and inflammation Yiqun Han, Yaobin Ouyang, Shouhai Zhu, Hangcheng Xu, Bin Chen, Ping Yin, Qin Zhou, Jinzhou Huang, Kuntian Luo, Zheming Wu, Huaping Xiao, Xinyi Tu, Jake A. Kloeber, Jiajun Jing, Xiaofeng Huang, Meng Xu Welliver, Zhenkun Lou, Robert Mutter
• 540 · PDF Cancer cells are sensitive to methionine cycle perturbation in low-lipid environments Diya Lakshmi Ramesh, Keene L. Abbott, Ryan Elbashir, Edrees H. Rashan, Raphael Ferreira, Matthew G. Vander Heiden
• 541 102 Cancer studies including differentially expressed potassium channel (KCN) genes reveal pH sensitivity with stochastic preservation of a proposed K + /H + initiated H + release strategy for pH reversal Marie E. Beckner
• 542 · PDF A novel one carbon pathway generates nuclear SAM for chromatin methylation in cancer Tiziano Bernasocchi
• 543 · PDF Prevalence and significance of PSAT1 expression in human cancer Fiete Gehrisch, Hendrina Contreras, Maximilian Lennartz, Katharina Möller, Nathalia Gorbokon, Martina Kluth, Claudia Hube-Magg, Maria Christina Tsourlakis, Nina Schraps, Florian Viehweger, David Dum, Andrea Hinsch, Christoph Fraune, Christian Bernreuther, Patrick Lebok, Guido Sauter, Till S. Clauditz, Till Krech, Andreas H. Marx, Ronald Simon, Eike Burandt, Sarah Minner, Stefan Steurer, Ria Schlichter, Seyma Büyücek
• 544 Dissecting the biological functions of various isoforms of ferredoxin reductase for cell survival and DNA damage response Kenichi Nakajima, Shakur Mohibi, Kyle Kenji Hong, Xinbin Chen, Jin Zhang
• 545 · PDF PFAS-mediated DRP1 deamidation couples mitochondrial dynamics to purine biosynthesis Xinchi Xie, Yongzhen Liu, Chao Qin, Jessica Carriere, Pinghui Feng

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