Late-Breaking Research: Immunology 1

• LB075 · PDF PAK4 inhibition enhances tumor immunity by inducing viral mimicry Libin Gao
• LB076 · PDF Targeting suv39h1 epigenetic silencing to induce viral mimicry and suppress glioblastoma growth Yi Sak Kim, Charles Spruck
• LB077 · PDF Natural killer (NK) cell therapies for breast cancer brain metastasis Timothy M. McMullen, Pascal Naef, Erika Zagni, Aaron J. Longworth, Isam Adam, Noah Wechter, Jacob Insua-Rodriguez, Lincy Antony, Dennis Ma, Eva Zhao, Sharmila Mallya, Tatyana Lev, Hannah Savage, Lei Tian, Delia F. Tifrea, Robert Edwards, Miguel A. Villalona-Calero, Ahmed Mohyeldin, Timothy E. O’Sullivan, Jianhua Yu, Kai Kessenbrock, Devon A. Lawson
• LB078 · PDF Highly plastic macrophage niches orchestrate acquired quiescence and reactivation in breast-cancer bone metastasis Noriko Gotoh
• LB079 · PDF Prostatic luminal epithelial cells in proliferative inflammatory atrophy display proinflammatory innate immune signaling activation that is absent in prostatic adenocarcinoma Thomas M. Steele, Jessica Hicks, Qizhi Zheng, Alan K. Meeker, Mindy K. Graham, Abhishek Shetty, Rulin Wang, Carolina Gomes-Alexandre, Fernanda Caramella Pereira, William G. Nelson, Sushant Kachhap, Srinivasan Yegnasubramanian, Angelo M. De Marzo
• LB080 · PDF Obesity contributes to varied efficacy of non-covalent KRAS G12D inhibitor in murine models of pancreatic ductal adenocarcinoma Sujith Sarvesh, Holly R. Stephens, Pia Muri, Henry Nnaemeka Ogbonna, Karen Aikhionbare, Jianqing Zhang, Dhana Sekar Reddy Bandi, Cherlene Hardy, Purnachandra Nagaraju Ganji, Bassel F. El-Rayes, Lyse A. Norian, Jeremy Foote
• LB082 · PDF Disrupting mismatch repair makes mismatch repair-proficient tumors immunogenic and induces CD8 T cell-dependent, but T cell receptor-independent, immune control of heterologous tumors in mice Haiwei Zhang, Ayijiang Yisimayi, Bowen Gu, Yuting Wang, Wayne M. Yokoyama, Sytse J. Piersma, Eduard Batlle, Daniele V. F. Tauriello, Judy Lieberman
• LB083 · PDF Gut microbiome signatures of survival and immunotherapy response in advanced thyroid cancer Ahmad Abubaker, Ashish V. Damania, Zoey R. Neale, Sabitha Prabhakaran, Yasmine M. Hoballah, Patient Mosaic Team, Naifa  Busaidy, Sarah Hamidi, FAST Consortium, Jennifer A. Wargo, Andrew  Futreal, Stephen Y. Lai, Nadim  J. Ajami, Anastasios Maniakas
• LB084 · PDF Oncogenic KRAS suppresses DNA sensing via CD9 by remodeling membrane tension to clear extracellular tumor DNA Di Cao, Weiyi Zhou, Zhixiong Li, Shixun Lu, Zhenlin Hou, Long Yu, Yuanjun Guan, Guoqiang Wang, Yifan Liu, Zhijie Huang, Hao Wang, Jingyi Dai, Cong Li, Jing Wang, Gong Chen
• LB085 · PDF Claudin-1 modulates the melanoma immune microenvironment to promote tumor growth and is a candidate therapeutic target for advanced melanoma Antonin Lallement, Frank Jühling, Zeina Nehme, Bujamin Vokshi, Guillaume Davidson, Emilie Crouchet, Thomas F. Baumert, Irwin Davidson
• LB086 · PDF Macrophage-dendritic cell-T-cell tetrads orchestrate antitumor immunity and response to checkpoint blockade Mehdi Chaib, Muhammad Aminu, Shelley Herbrich, Mahshid Arabi, Yue Xuan, Akshay Basi, Anna Casasent, Marc Macaluso, Kenneth Hu, Matthew Gubin, Xi Chen, James Mancuso, Sreyashi Basu, Sonali Jindal, Jared Burks, Stephanie Watowich, Jia Wu, James Allison, Padmanee Sharma
• LB087 · PDF Regulatory T cells control anti-tumor microglia function in breast cancer brain metastasis Isam Adam, Pascal Naef, Erika Zagni, Aaron Longworth, Hannah Savage, Jacob Insua-Rodriguez, Noah Wechter, Lincy Antony, Timothy McMullen, Eva Zhao, Francesco Marangoni, Devon Lawson
• LB088 · PDF Identifying mechanisms of immune suppression in KRAS-inhibitor resistance in NSCLC Samrat Kundu, Amrita Barua, Sofia Garza, David Peng, Jared Fradette, Don Gibbons

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