Experimental Chemoprevention and Interception: Data and Tools

• 942 Target validation and high-throughput screening assay development for natural product discovery for cancer prevention and interception Yurong Song, Brandon Somerville, Kajal Biswas, Karim Baktiar, Liankun Song, Sara Sanders, Tanja Grkovic, Ligia A. Pinto, Ana Catarina Menezes, Paul P. Liu, Matthew J. Hart, Chinthalapally V. Rao, Shugeng Cao, Xin Chen, Xu Wu, Xiaolin Zi, Mark J. Henderson, Barry R. O'Keefe, Altaf Mohammed, Robert H. Shoemaker
• 943 · PDF Chemoprevention of hepatocellular carcinoma by next-generation antipsychotic aripiprazole Nevena Slović, Sumit Mishra, Subhojit Paul, Marine A. Oudot, Frank Jühling, Hiroaki Kanzaki, Julien Moehlin, Margaux Denos, Anouk Charlot, Sarah C. Durand, Courtney Katz, Cloé Gadenne, Emanuele Felli, Joachim Lupberger, Emilie Crouchet, Yujin Hoshida, Thomas F. Baumert
• 944 The combination of EPA and Naproxen prevents iCAF polarization and attenuates inflammation associated with Pirc tumor development Niti Jani, Ryan Beach, Michael Martinez, Shizuko Sei, Vignesh Gunasekharan, Daniel W. Rosenberg
• 945 Chemoprevention of triple-negative breast cancer originating from cancer stem cells using OXPHOS inhibitors Esra Akkus, Cemile Uslu, Mert Güngör, Beyza Şimbil, Elif Uzun, Etna Abad, Alex Lyakhovich
• 946 Liposomes encapsulated chloroform fraction of Cassia fistula L. bark enhances anticancer efficacy in ehrlich ascites carcinoma mice model Satwinderjeet Kaur, Rasdeep Kour
• 947 Mammary gland architectural modulation with a natural galactagogue Asparagus racemosus (Shatavari root extract) and its impact against triple negative breast cancer (TNBC) tumorigenesis Md. Imtiazul Kabir, Robin Kumar, Lakshmi Sai Pratyusha Bugata, Komal Raina
• 948 · PDF TRAIL inducing drug, ONC201 prevents adenocarcinoma in transgenic KRAS G12V mouse lung cancer model Karthikkumar Venkatachalam, Gopal Pathuri, Nicole Stratton, Anil Singh, Nandini Kumar, Shizuko Sei, Vignesh Gunasekharan, Chinthalapally V. Rao, Venkateshwar Madka
• 949 · PDF Prevention of insulin receptor isoform A formation inhibits MASH-driven hepatocellular carcinoma Yanting Wang, Manasi Das, Panyisha Wu, Yunpeng Yang, Isabella Maranan, Liping Zeng, Yichun Ji, Deepak Kumar, Nicholas Webster
• 950 · PDF Efficacy of androgen receptor inhibitor, Apalutamide, in intercepting bladder cancer in a BBN-induced rat bladder tumor model Venkateshwar Madka, Gopal Pathuri, Anil Singh, Surya P. Singh, Anh Bao, Nicole Stratton, Shizuko Sei, John Clifford, Chinthalapally V. Rao
• 951 · PDF STAT3 inhibitor TTI-101 effectively intercepts bladder cancer in a carcinogen-induced rat bladder tumor model Venkateshwar Madka, Gopal Pathuri, Anil Singh, Nicole Stratton, Anh Bao, David J. Tweardy, Shizuko Sei, Vignesh Gunasekharan, Chinthalapally V. Rao
• 952 · PDF Silibinin induced mast cell regulation: Potential immunomodulation via ODC1 in pancreatic cancer prevention and therapy Neha Mishra, Sandeep Paudel, Komal Raina, Chapla Agarwal, Rajesh Agarwal
• 953 Chemopreventive effects of Rheum webbianum against colorectal cancer via modulation of Wnt/beta-catenin and TGF-beta signaling: Insights from in-vitro and in-vivo studies Umer Majeed Khaja, Reena Singh, Showkat Ahmad Ganie
• 954 Dabigatran etexilate potentiates the anti-tumor effects of anti-CTLA4 antibody through remodeling the immune microenvironment in a syngeneic mouse model of MyC-CaP cells Liankun Song, Matthew Gozon, Andrewtrung Le, Jun Xie, Xiaolin Zi
• 955 · PDF Development of HiBiT tagged high-throughput screening assay for the discovery of SKP2 targeting degraders in prostate cancer Liankun Song, Merry Chai, Matthew Gozon, Jun Xie, Saiyang Zhang, Xiaolin Zi
• 956 The repurpose of dabigatran etexilate for improving prostate cancer prevention and treatment through down-regulating Myc and E2F target genes and inducing autophagic apoptosis Guanxing Zhai, Vinh Le, Liankun Song, Yixi “Michael” Wu, Xiaolin Zi
• 958 Novel syngeneic models for evaluating therapies targeting EGFR L858R/T790M and EGFR L858R/T790M/C979S resistance mutations in NSCLC Lei Ci, Kai Zhou, Jiangyan Liu, Ruilin Sun
• 959 · PDF Harnessing Id1 as a Biomarker in a Plasmid Reporter System for Cervical Cancer Abbigael V. Eli, Benjamin B. Kasten, Yolanda Hartman, Rebecca C. Arend, Jason M. Warram
• 960 · PDF Dysregulation of the islet hormone cholecystokinin drives obesity-associated pancreatic cancer Daniel C. McQuaid, Cathy C. Garcia, Aarthi Venkat, Christian F. Ruiz, Christy Zheng, Smita Krishnaswamy, Mandar Deepak Muzumdar
• 961 · PDF HSC-humanized mouse model: Invivo CAR-T mediated B-cell depletion and application in targeted drug screening Xiaolei Qiu, Lei Ci, Ruilin Sun
• 962 Phenylacetaldehyde induces apoptosis through endoplasmic reticulum stress and potentiates the effect of 5-FU treatment in colorectal cancer Sylvain Ferrandon, Cheng Kong, sara soltani tehrani, Joseph Fedro, Rami-James Aoun, Zeneng Wang, Chureeporn Chitchumroonchokchai, Huanlong Qin, Steve Clinton, Matthew F. Kalady
• 963 · PDF Preclinical testing of A 2B adenosine receptor inhibitor PSB1115 for pancreatic cancer immunoprevention Alyssa M. Waller, Lincoln Strickland, MacKenzie Demmel, Erika Y. Faraoni, Michelle I. Savage, Shizuko Sei, John L. Clifford, Powel H. Brown, Eduardo Vilar-Sanchez, Florencia McAllister, Jennifer Bailey-Lundberg
• 964 Accelerated Pirc rat model for animal efficacy trials for prevention and treatment of colorectal cancer Rashim Singh, Vesna Tumbas Saponjac, Trang Le Nu Huyen, Jie Yang, Jie Chen, Taijun Yin, Songpol Srinual, Ming Hu
• 965 · PDF A novel agonist of CD137, SA-4-1BBL, as a single agent halts spontaneous breast cancer progression Yongyong Li, Sarita Rani, Feyza Nur Arguc, Yichen Wang, Daniel Davis, Esma S. Yolcu, Haval Shirwan
• 966 · PDF Development of a humanized IL-17A/IL-17F mouse model for preclinical efficacy studies of IL-17-related diseases Huacheng He, Ailin Yang, Shuang Li, Qingqing Qi, Yi Li, Ruilin Sun
• 967 · PDF Prevention and interception of triple-negative breast cancer and its metastasis to the brain with brain-permeant L024 Atieh Hajirahimkhan, Alexander D. Eremin, Elizabeth Bartom, Saktimayee M. Roy, Daniel M. Watterson, Susan E. Clare, Seema A. Khan
• 968 · PDF Fully human anti-PD-L1 antibodies with tumor cytotoxicity: Screening in SmocMab mice Ningning Ge, Huacheng He, Lei Ci, Ruilin Sun, Dongxiao Feng
• 969 · PDF Humanized TFR1 knock-in mice: A powerful platform for evaluating TFR1-targeting brain shuttles Liping Feng, Shuang Li, Zixuan Cao, Yi Li, Dongxiao Feng, Ruilin Sun
• 970 · PDF A Jak2-V617F knock-in mouse model for assessing therapeutic efficacy in myeloproliferative neoplasms Ailin Yang, Shuang Li, Qingqing Qi, Yi Li, Ruilin Sun

在完整检索应用中浏览本分会场 →