Stem Cell Plasticity and Lineage Reprogramming in Cancer

• 822 · PDF Netrin-1/UNC5B-TFF3 axis modulates cancer stem cells self-renewal and chemoresistance in metastatic colorectal cancer Morgan Brisset, Kristina Radkova, Andrea Paradisi, Lea Stephan, Robin Wagner, Cyril Degletagne, Fabien Luiggi, Lisa Frydman, Alexander Heriot, Corina Behrenbruch, Tamara Vu, Frédéric Hollande, Patrick Mehlen
• 824 · PDF PPARdelta overexpression drives transformation of multiple gastric progenitor and stem cells and tumorigenesis in mice Xiangsheng Zuo, Yi Liu, DAOYAN WEI, James C. Yao, Imad Shureiqi
• 825 Bone marrow from acute myeloid leukemia (AML) and multiple myeloma (MM) patients can be used to evaluate target expression and on-target efficacy for novel antibody drug conjugates (ADCs) Aisha Mergaert, Coranna Akdemirbey, Mariah Suchan, Tara Murray, Emer Clarke
• 826 · PDF Investigating TWEAK-mediated regulation of ovarian cancer cell survival Harshada Sapre, Mikella Robinson, Carrie House
• 827 Actin cytoskeleton modulation reprograms resistant GBM spheroids and GSCs, enhancing response to IR and temozolomide in vitro and in vivo Yuli Thamires Magalhães, Viktor Kalbermatter Boell, Letícia Ramos Molica, Donna Joe, Fabio Luis Forti
• 828 · PDF Investigation of developmental LIN28/ let-7 /SOX2/SOX9 feedback loop during cell migration and metastasis Indhujah Thevarajan, Maria Osuna, Bareun Kim, Jihan K. Osborne
• 829 Infiltration of hematopoietic stem cells (HSC) is associated inversely with cell proliferation, with better patient survival, and its reduction by neoadjuvant chemotherapy relates with poor survival in breast cancer Masanori Oshi, Rongrong Wu, Li Yan, Takashi Ishikawa, Itaru Endo, Kazuaki Takabe
• 831 The functional crosstalk between tissue transglutaminase (TG2) and CD24 enhances cancer stem cell traits and therapy resistance in high grade serous ovarian cancer Rohit Pravin Nagare, Habeebunnisa Begum, Ben Wamba, Jogender Tushir-Singh, Fabrizio Pin, Salvatore Condello
• 833 · PDF Desmoglein-2 carrying cancer stem cell-derived extracellular vesicles promote lung cancer aggressiveness Prita Pandya, Aamena Ahmed, Nayya Murray, Dania S. Al-Qasrawi, Anaya Y. Clarke, Reagan Carris, Verline Justilien
• 834 · PDF Unveiling the association of cancer stem cell markers with survival in follicular lymphoma patients Xin Zhang, Olivia White, Daniel Ashley, Betty Chung, Li Li
• 835 · PDF Modeling endometrial cancer using iPSC-derived endometrial organoids integrating genetic determinants of ethnicity Sueanne Chear, Simon Gayther, Kate Lawrenson
• 837 · PDF IDH mutations disable the tumor suppressive activity of GSX2 to promote gliomagenesis Yi Xiao, Diana D. Shi, Lei Guo, Ethan Neumann, Michael M. Levitt, Pranita Kaphle, Tracey Shipman, Haocheng Li, Feng Cai, Denise M. O. Ramirez, Lauren G. Zacharias, Zhenkang Chen, Mathew Lin, Vinesh T. Puliyappadamba, Tao Chen, Milan R. Savani, Salvador Peña, Janaka Wansapura, Thomas P. Mathews, Prashant Mishra, Yoon Jung Kim, Prithvi Raj, Timothy E. Richardson, Jian Xu, Stephen C. Mack, Gilbert J. Rahme, Bradley E. Bernstein, Ralph J. DeBerardinis, Itay Tirosh, Mario L. Suvà, Lin Xu, Kalil G. Abdullah, Samuel K. McBrayer
• 838 · PDF Single cell multiomic profiling of heterogenousPROCR+ cells in mouse mammary gland and its implication for breast cancer Jose Silva, Koon-Kiu Yan, Erin Nekritz, Jiyang Yu
• 839 Single cell cloning iPSCs with the Pala single cell sorter preserves colony stemness and cell viability for high-throughput cell line engineering workflows Bhamini Purandare, Francisco Ramirez, Ryan McComb, Chris Heger
• 840 · PDF Multi-tissue modeling of BRCA cancers using iPSC-derived organoids platform Nur Yucer, Alyssa Okimoto, Subash Dhungana, Dean Bacich, Rebecca Webster, Beatriz German Falcon, Michelle Jones, Sarah Parker, Bobbie Jo Rimel, Beth Y. Karlan, Leigh Ellis, Matthew Freedman, Robin J. Leach, Xiaojiang Cui, Kate Lawrenson, Simon Gayther
• 841 · PDF Maternal obesity reprograms intestinal stem cells to elevate colorectal cancer risk in offspring Gourab Lahiri, Karla Mullen, Yesenia B. Millan, Swathi Sankar, Dominic R. Saiz, Thomas H. McDermott, Madeline Blatt, Abhigyan Shukla, Khashayarsha Khazaie, Miyeko D. Mana
• 843 · PDF Protection of human bone marrow MSC from room air oxygen during isolation accelerates cell growth Alicia D. Henn, Shannon L. Darou, Collins E. Gbegbeawu, Syed A. Mustafa
• 844 · PDF Investigating the ability of foxo1 to maintain stem cells Stella Aime Rios, Megan E. Keniry
• 845 Tumor-associated mesenchymal stem cells accumulate in high oxidative phosphorylation regions of peritoneal dissemination in gastrointestinal cancers Nobuhiko Kanaya, Yu Mikane, Shinji Kuroda, Eri Takeda, Makoto Matsumoto, Kosuke Yunoki, Yudai Mimata, Hitoshi Minagi, Tetsuya Katayama, Daisuke Kadowaki, Masashi Hashimoto, Yoshihiko Kakiuchi, Shunsuke Kagawa, Hiroshi Tazawa, Toshiyoushi Fujiwara
• 846 Evidence of functional cytotoxic T-cell responses to induced pluripotent stem cells (IPSCs): Paving the way for IPSC-derived cancer vaccines Valentine Feyants, Catherine Martel, Christophe Desterke, Mequa Maatoug, Diana Chaker, Ali G. Turhan, Annelise Bennaceur Griscelli, Frank Griscelli
• 847 · PDF The role of tissue renewal in early-onset colorectal cancer Bruce M. Boman, Anh Nguyen, Chi Zhang
• 848 Redox regulation of breast cancer metastasis via phenotypic and metabolic adaptation Rachel Hazan, Viney Kumar, Outhiriaradjou Benard, premprashant chaudhary, mahaldeep kaur, Ian Myles, Bethesda, Larry Norton
• 850 SOX9 and SEMA7A regulate epithelial cell plasticity in the postpartum mammary gland with implications for postpartum breast cancer Lauren M. Cozzens, Brendan Hinckley, Sonali Jindal, Virginia F. Borges, Pepper Schedin, Traci Renae Lyons
• 851 · PDF BMP inhibition is an effective treatment for targeting stem-like glioblastoma cell states Davey (Cheng Zhe) Li, Michael Luo, Phuong U. Le, Maryam Safisamghabadi, Tuong V. Kieu, Andy Nkili, Paul Wambo, Rozica Bolovan, Javad Nadaf, Kevin Petrecca

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