Liquid Biopsies: Circulating Nucleic Acids 2

• 2582 · PDF Advancing liquid biopsies via integrated CRISPR-based extracellular vesicle RNA and protein analyses Cesar M. Castro, Jayeon Song, Hakho Lee
• 2583 · PDF Tumor-informed circulating tumor DNA dynamics reflect aggressive histology and radiologic disease status in renal cell carcinoma Eric Martin, Eun-mi Yu, Annika Murthi, Hongkun Wang, Laura Linville, Jeanny B. Aragon-Ching
• 2584 · PDF Methylation signatures from liquid biopsies predict anti-EGFR therapy response in patients with colorectal cancer Xuwen Li, Mingyang Cai, Shile Zhang, Nicole Zhang, Reagan Barnett, Tingting Jiang, Kota Ouchi, Yoshiaki Nakamura, Kimberly Banks, Justin Odegaard, Darya Chudova
• 2585 · PDF Plasma cell-free DNA nucleosome footprints in metastatic castration-resistant prostate cancer (mCRPC) Denisa Bogdan, Jan Rekowski, George Seed, Claudia Bertan, Jane Goodall, Gemma Fowler, Penelope Flohr, Christine Geffriaud-Ricouard, Mustapha Chadjaa, Sandrine Mace, Isaac Lazzeri, Ellen Heitzer, Suzanne Carreira, Wei Yuan, Johann S. de Bono
• 2586 · PDF Investigating a Wilms tumor DNA methylation signature in liquid biopsies Mariusz Shrestha, Arteen Torabi-Marashi, Marina Dutra, Sanaa Choufani, Trevor J. Pugh, Rosanna Weksberg, Jack Brzezinski
• 2587 Development of a methylated gene panel for detection of cell-free, metastatic prostate cancer DNA in plasma Gang Yu, Mary Jo Fackler, Liqun Zhang, Wenfei Xia, Roshni Saravanan, Ezra Baraban, Eunice Van Den Berg, Adam Botha, Pamela Michelow, Reubina Wadee, Maureen Joffe, Wenlong Carl Chen, Thomas Pisanic, Michelle Petri, Jun Luo, Channing Paller, Samuel Denmeade, Leslie Cope, Saraswati Sukumar
• 2588 · PDF Monitoring ESR1 and other mutations linked to resistance with a tumor-informed MRD test: Analytical validation and real world data Jason Harris, John M. Lyle, Gabor Bartha, Sean M. Boyle, Josette Northcott, Devayani Bhave, Claudia Aliguillen, Shuyuan Ma, Rachel M. Pyke, Steven Dea, Dan Norton, Erin Ayash, Richard O. Chen
• 2589 · PDF Prospective verification of OvaPrint and multi-omic profiling for precise adnexal mass classification Thomas Simon, Lynda D. Roman, X. Mona Guo, Ben Yi Tew, Gerald C. Gooden, Monica Neuman, Emma Barber, Elisa Romeo, Todd Holscher, Renee Wunderley, Danielle Goldberg, Krishna Morampudi, Dalia Daujotyte, Monique Spillman, Bodour Salhia
• 2590 · PDF Urine cfDNA 4-mer end-motif signatures outperform other fragmentomic features for tissue-of-origin classification in genitourinary cancers Jessica Linford, Pradeep S. Chauhan, Irfan Alahi, Yohan Kim, Arpit Panda, Nathan Colon, Ryan Mueller, Faridi Qaium, Eric H. Kim, Melissa A. Reimers, Zachary L. Smith, Woodson W. Smelser, Fabrice Lucien-Matteoni, Aadel A. Chaudhuri
• 2591 · PDF Sequence and structural DNA alterations in the circulation of patients with cancer Daniel C. Bruhm, Carolyn Hruban, Adrianna L. Bartolomucci, Akshaya V. Annapragada, Sarah Short, Shashikant Koul, Kaui P. Lebarbenchon, Julia S. Johansen, Inna M. Chen, Andrei Sorop, Razvan Iacob, Speranta Iacob, Liana Gheorghe, Simona Dima, Katherine A. McGlynn, Manuel Ramírez-Zea, John Groopman, PLCRC-MEDOCC group, Remond J. A. Fijneman, Gerrit A. Meijer, Zachariah H. Foda, Jillian Phallen, Robert B. Scharpf, Victor E. Velculescu
• 2592 · PDF Nocturnal rise in circulating tumor DNA in a subset of metastatic colorectal cancer patients Ekaterina S. Kuligina, Aleksandr S. Martianov, Liliya S. Baboshkina, Arina S. Perevalova, Yana V. Belysheva, Anastasia N. Ershova, Tatiana A. Laidus, Aram A. Musaelyan, Ekaterina M. Anokhina, Gulfiia M. Teletaeva, Aglaya G. Iyevleva, Evgeny N. Imyanitov
• 2593 · PDF Enspyre MRD: Validation of an ultra-sensitive kitted MRD solution at low sequencing depth Magdalena Stolarek-Januszkiewicz, Sophie Hackinger, Sarah Diels, Katarzyna Anton, Amy Lovell, Ernesto Lowy-Gallego, Ana-Luisa Silva, Maria Litovchenko, Bart Tegenbos, Emmanuel Rivière, Dirk Goossens, Nathalie Bernard, Justyna Mordaka, Iyelola Turner, Lisa Van den Bossche, Lien Heyrman, Jan Van de Velde, Pieter Mestdagh, Jurgen Del Favero, Barnaby Balmforth
• 2594 · PDF A deep sampling and single molecule digital counting assay for rare molecule detection Danny Overman, Cindy Wang, Jung won Keum, Jesse Soliman, Emily Blair, Eleen Shum, Tricia Zwiefelhofer
• 2595 A novel dual-strand whole-genome sequencing (WGS) method for ultra-sensitive molecular residual disease detection (MRD) Andrew Slatter, Jessica Moore, Esther Musgrave-Brown, Dhamayanthi Pugazhendhi, Trevor Ho, Alex Calderwood, Dale Weekes, Seong Won Cha, Christopher Edlund, Sven Bilke, Huihong You, Chris Truong, Jeff Tsai, Khai Luong, Li Liu, Yunjiao Zhu, Jeff Fisher, Traci Pawlowski, James Han, Fiona Kaper, Cande Rogert
• 2596 · PDF Ultrasensitive multiplex ddPCR for integrated genomic-epigenomic ctDNA detection in colorectal cancer Ya Zhou, Yuwei Ni, Xingyu Yang, Qiancheng You, Jing Su, Yunpeng Zhang, Xiaoling Li, Xinyue Kang, Jiayue Xu, Zhihong Zhang, Bingsi Li
• 2597 Baseline cfDNA fragmentomics identifies multiple myeloma patients at risk of early progression Dor David Abelman, Jenna Eagles, Aimee Wong, Saumil Shah, Jeffrey Bruce, Stephanie Pedersen, David S. Scott, Cecilia Bonolo de Campos, Signy Chow, Darrell White, Irwindeed Sandhu, Kevin Song, Esteban Braggio, Shaji Kunnathu Kumar, Alli Murugesan, Tony Reiman, A. Keith Stewart, Suzanne Trudel, Trevor J. Pugh
• 2598 · PDF Analytical validation of an ultra-high sensitivity tumor-informed MRD assay Ashley Acevedo, Kelly Colbert, Kyle Trettin, Alexander Ham, Genevieve Gould
• 2599 · PDF Methylation-based circulating tumor DNA predicts recurrence in definitively treated non-small cell lung cancer (NSCLC) Jisoo Lee, Eun Ji Song, Youngjun Lee, Jongsu Kim, Yuchan Kim, Anthony Wong, Sanghwa Kim, Liam I. Chung, Young Kwang Chae
• 2600 · PDF Investigating treatment response and resistance in non-small cell lung cancer patients through epigenetic profiling of plasma nucleosomes Christoffer T. Maansson, Simone Stensgaard, Emma Pedersen, Anders Lade Nielsen, Peter Meldgaard, Boe Sandahl Sorensen
• 2601 · PDF Biomarker tail genes in blood plasma cell-free RNA enable accurate detection of prostate cancer Annelien Morlion, Philippe Decruyenaere, Kathleen Schoofs, Jasper Anckaert, Nickolas J. Ramirez, Justine Nuytens, Eveline Vanden Eynde, Kimberly Verniers, Celine Everaert, Guy Brusselle, Steven Callens, Filomeen Haerynck, Dimitri Hemelsoet, Eric Hoste, Jo Lambert, Nicolaas Lumen, Fritz Offner, Koen Paemeleire, Vanessa Smith, Lies Van den Eynde, Jo Van Dorpe, Amber Vanhaecke, Hans Van Vlierberghe, An Mariman, Olivier Thas, Jo Vandesompele, Pieter Mestdagh
• 2602 · PDF Impact of targeted therapies in cancers classified as TMB-high by liquid biopsy: Insights from the Gustave Roussy molecular tumor board Adrien Mouren, Berenger POIRIER, Antoine Italiano, Matthieu Roulleaux Dugage, Yohann Loriot, Antoine Hollebecque, Anas Gazzah, Barbara Pistilli, Christophe Massard, Cyril ROUSSEL-SIMONIN
• 2603 · PDF Comparing methylation signatures across 15 cancer types and 7 subtypes Harry Mickalide, Joel Rodriguez-Medina, Fernando L. Mendez, Murat Can Cobanoglu, Scott Dashner, Yuqian Jiang, Kevin Chan, Joshua N. Burton, Trupti Kawli, Johannes G. Reiter, Matthew Rabinowitz, Alexey Aleshin
• 2604 · PDF Postoperative lymphatic exudate as a proximal liquid biopsy source in muscle-invasive bladder cancer Zhuosheng Gu, Zachary Costliow, Seka Lazare, Abbey Crittenden, Adam Harmon, Megan Rivera, Ashley Tellis, Samuel Espinoza, Adam Benson, Marra Francis, Ankeet Shah, Michael R. Abern, Gautum Agarwal, Wendy Winckler
• 2605 · PDF Concordance evaluation of plasma whole-exome sequencing (pWES) and tissue whole-exome sequencing (tWES): A pilot study in non-small cell lung cancer (NSCLC) Bingjie Dong, Zhijiao Wang, Carol E. Peña, Xiaoqiao Liu, Gefei Zeng
• 2606 · PDF A liquid biopsy assay of estrogen receptor activity predicts response to giredestrant in ER+/HER2− advanced breast cancer Ann E. Collier, Jon Beagan, Travis Clark, Kristian Cibulskis, Corrie Painter, Mary McGillicuddy, Aparna Gorthi, Khoi Nguyen, James Sullivan, Richard Schwab, Jing Zhu, Pablo Perez-Moreno, Tharu M. Fernando, Matthew Eaton, Carl J. Barrett

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