Immunomodulatory Effects of Targeted Therapies

• 2557 · PDF Glucocorticoids inhibit the GARP/TGF-betaaxis initiating immune-dependent melanoma control Charles H. Earnshaw, Poppy Dunn, Shih-Chieh Chiang, Agrin Moeini, Maria A. Koufaki, Eduardo Bonavita, Massimo Russo, Laetita Nebot-Bral, Kimberley Hockenhull, Erin Richardson, Anna Pidoux, Charlotte R. Bell, Alexander R. Baker, Richard Reeves, Robert Sellers, Sudhakar Sahoo, Victoria Fife, Matthew G. Roberts, Theophile Bigirumurame, Caroline Dive, Julia A. Newton-Bishop, Jeremie Nsengimana, Christopher E. M. Griffiths, Santiago Zelenay
• 2558 · PDF Multi-omic single-cell assessment of castration-resistant prostate cancer patients receiving 177 Lu-PSMA-617 and pembrolizumab shows timing of radioligand therapy alters immune response Anusha Muralidhar, Karen Law, Zenghua Fan, Shloka Shukla, Aram Lyu, Serena Kwek, David Y. Oh, Michael Evans, Rahul R. Aggarwal, Lawrence Fong
• 2559 · PDF Identifying cancer cell intrinsic regulators of radiation-induced interferon signaling Olivia Kaneko, Bon Ham Yip, Arnav Mehta, Nir Hacohen, Ryan J. Park
• 2560 · PDF Radiotherapy shapes memory T cell dynamics and region-specific PD-1 expression in the glioblastoma microenvironment Hsin-Yu Sherry Liu, Sanghee Lee, Itzel Gutierrez, Jasmine Borroel, Paris Offor, Emily Eastwood, Javier Rodriguez, Kristen Buck, Derrick Gorospe, Elizabeth Valencia, Catherine Elix, Bridget Corcoran, Manuel Reyes, Samantha Lin, Raffaella Pippa
• 2562 · PDF Quantitative and functional immune reprogramming induced by a nanomedicine in breast cancer model Mathilde Dacos, Léa Plantureux, Sarah Giacometti, Joseph Ciccolini, Raphaelle Fanciullino
• 2563 · PDF mTOR inhibition augments antitumor immune response by reprogramming the TP53 -mutant, immune-cold HNSCC tumor microenvironment Priyatosh Nath, Alok Khandelwal, Tara Moore-Medlin, Chun Li, Cherie-Ann Nathan
• 2564 · PDF Investigating the combination of natural killer immunotherapy with radiation therapy for muscle invasive bladder cancer Fatima Inigo, Jose Mansure, Eva Michaud, Brian Meehan, Tanner Connell, Ciriaco Piccirillo, Wassim Kassouf
• 2565 · PDF mTOR as a mechanistic biomarker of FLASH radiotherapy: Implications for immune-modulated melanoma treatment Madison Hawkins, Joshua Knight, Camden VanTassell, Landen Barnett, Gennie Lynne Parkman, Dani Johnson-Erickson, Ramesh Rengan
• 2566 · PDF KRAS G12D inhibition enhances macrophage-mediated anti-tumor immunity via STING activation Xiaoe He, Xiangyan Jiang, Wengui Shi, Long Qin, Tao Wang, Zuoyi Jiao
• 2567 · PDF Axl is a negative regulator of type I IFN in cDC1s hindering anti-tumor immunity Isaac Gonzalez, Eslam A. Elghonaimy, Qiongwen Zhang, Isaac Montgomery, Peter Q. Leung, Arely P. Rodriguez, Rolf A. Brekken, Todd A. Aguilera
• 2569 Particle therapy, ATM and PD-1 inhibition for pMMR rectal cancer Cameron M. Callaghan
• 2570 · PDF Reprogramming T-cell networks to overcome immune evasion in ovarian cancer relapse Denarda Dangaj Laniti
• 2572 · PDF Pharmacological targeting of CTPS1 elicits macrophage-mediated anti-leukemia immunity Meng Liu, Lei Zhang, Xin He, Haojie Dong, Yang Li, Shuaishuai Ge, Guohua Wu, Yadav P. Umesh, Wei Chen, Pinghui Feng, Guido Marcucci, Ling Li
• 2573 · PDF Identification and characterization of platinum agent-induced chemoimmunomodulation in triple-negative breast cancer Mariana Makarem, Kathleen Streeks, Claudia Perez Perez, Iasmim Lopes de Lima, Mohammed Gbadamosi
• 2574 · PDF Identification and characterization of chemoimmunomodulatory induction trajectories in breast cancer via unsupervised transcriptomic analyses of pre- and post-treatment specimens Iasmim L. de Lima, Kathleen H. Streeks, Elizabeth Molchan, Mariana S. Makarem, Kennedy L. Coleman, Mohammed O. Gbadamosi
• 2575 · PDF Identification and characterization of anthracycline-induced chemoimmunomodulation in triple-negative breast cancer Kennedy L. Coleman, Kathleen Streeks, Mariana Makarem, Iasmim Lopes de Lima, Mohammed Gbadamosi
• 2576 Gut-targeted antibiotic modulation enhances radiotherapy response in NSCLC and uncovers epigenetic and microbiome-driven immune programs enabling live biotherapeutic design Steven J. Feigenberg, Francesca Costabile, Ceylan Tanses, Kyle Bittinger, Divyansh Agarwal, Roddy O'Connor, Jeffrey Bradley, Amit Maity, Benjamin A. Garcia, Andrea Facciabene
• 2577 Free and encapsulated tunicamycin significantly enhances the suppression of PD-L1 by gemcitabine through blocking K-Ras G12D expression in pancreatic ductal adenocarcinoma cells Axel Hugo Breier, Sunil P. Upadhyay, Ojaswitha Ommi, Stefan Bossmann, Sushanta K. Banerjee, Snigdha Banerjee
• 2578 · PDF Clinical feasibility study of Optim.AI 2.0, a co-culture high-content functional precision platform for predicting combinatorial immunotherapy response Sharon Pei Yi Chan, Masturah Rashid, Jhin Jieh Lim, Weng Tong Ho, Edward Kai-Hua Chow
• 3806 · PDF Development of a novel CAR T-cell therapy targeting thymic carcinoma Layla Ahmadi, Malak Khalifeh, Dimitar Donovski, DuyKhanh Pham Ceppa, Patrick Loehrer, Rohan Maniar, Huda Salman

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