Mechanisms of Drug Resistance 2

• 1781 · PDF Improving response of pancreatic cancer to losartan: Mechanistic insights and implications for personalized therapy Heena Kumra, Ryo Morisue, Benjamin E. Wolf, Vasiliki Salameti, Sonu Subudhi, Nilesh P. Talele, Eric F. Zaniewski, Robert Morris, Tsion H. Tale, Karim El-Marouk, Cora Schueller, Mariagiovanna Barresi, Jennifer Schulz, Halil I. Corbali, Rieke Schleinhege, Peigen Huang, Pascal Bernatchez, Wilhelm Haas, Yves Boucher, Dai Fukumura, Rakesh K. Jain
• 1782 · PDF Exome-scale CRISPR screening reveals master controllers of cell state maintenance in high-risk neuroblastoma Grace McKay-Corkum, Stephanie Nance, Noha AM Shendy, Shilpa Narina, Shondra Miller, Alex Carisey, Qiqi Jin, Jiyang Yu, Adam D. Durbin
• 1783 · PDF ELF3-driven epigenetic reprogramming creates ERK pathway dependency in SERD-resistant ER+ breast cancer Na Zhang, Myles A. Brown, Rongbin Zheng, Kaifu Chen
• 1784 · PDF Mechanistic characterization of (Z)-endoxifen in ESR1-mutant and endocrine-resistant breast cancer Sandra Suarez Hammer, Alina Ustiugova, Anastasia Shneyderman, Alexander Veviorskiy, Khadija M. Alawi, Mikhail Korzinkin, Lucia Beaulieu, Hayley Erickson, Scott M. Blackburn, H. Lawrence Remmel, Steven Quay
• 1785 · PDF Aspects of the YBX1-dependent mechanism of drug resistance in hepatocellular carcinoma Yamile Abuchard Anaya, Ana Ayala Pazzi, Veerababu Nagati, Kaylee Renteria, Denise Soto, Manish Tripathi
• 1786 · PDF Convergent FGFR-JAK signaling reprograms luminal identity and drives endocrine resistance in HR⁺ breast cancer Yucheng Zeng, Ruixin Liu, Xiaoyan Qiang, Jean Fan, Caixia Sun, Hanlin Zeng, Peng Peng
• 1787 · PDF Inhibition of MAOA suppresses intracrine androgen biosynthesis and enhances abiraterone treatment in castration-resistant prostate cancer Kaisheng Yuan, Hongling Li, Wen Guan, Jing Wei, Boyang Wu
• 1788 · PDF Cysteine accumulation as a driver of resistance to bortezomib Jennifer A. Brain, Sarah M. Chang, Maximilian Kobiesa, Leah G. Rector, Kelli J. Che, Zhaoqi Li, Sky H. Kim, Matthew G. Vander Heiden, Lucas B. Sullivan
• 1789 · PDF RNA isoform discovery and quantification with SMART-Seq® mRNA Long Read (v1 and v2) kits Jackson Peterson, Yue Yun, Lisa Welter, Kazuo Tori, Alan Du, Yana Ryan, Ning Ma, Rachana Kumar, Shiyi Yin, Mike Covington, Shuwen Chen, Elena Shagisultanova, Mohammad Fallahi, Bryan Bell, Andrew Farmer
• 1791 · PDF Targeting succinate dehydrogenase impairs the proliferation of ER+ breast cancer cells Anil Kumar Yadav, Lu Jin, Robert Clarke
• 1792 Comprehensive identification of factors involved in the resistance mechanism of a novel cereblon modulator in multiple myeloma cells Sho Osawa, Tomofumi Yamamoto, Rina Tamaru, Natsumi Seki, Maiko Matsushita
• 1793 · PDF RAC2 as a mediator of drug resistance in triple-negative breast cancer Antonisha R. McIntosh, Ngoc Voung, Destiny Ball, Perrin Black, Alayjha Edwards, Qingguo Wang, Amos M. Sakwe
• 1794 · PDF m 6 A-mediated control of kinase reprogramming in endocrine therapy-resistant breast cancer Attila Szenasi, Enakshi Sivasudhan, Santiago Haase, Austin Whitman, Kate D. Meyer, Philip M. Spanheimer
• 1795 · PDF Cooperative role of ESR1 mutations and midasin in endocrine resistance and the therapeutic potential of dual targeting Mounika Pamukuntla, Bipika Banjara, Manasa Kotina, Afia Ohemeng, Alicia Hudson, Michael Davidson, Jillian L. Pope, Selina F. Darling-Reed, Elizabeth Henderson, Simak Ali, Syreeta Tilghman
• 1796 · PDF Lineage-specific survival vs proliferative enzalutamide resistance states as potential drivers of prostate cancer disparities Richard Van, Mira V. Han, Desh P. Sharma, Ajay Singh, Ranjana Mitra
• 1798 · PDF Nicotinamide phosphoribosyltransferase (NAMPT) inhibitor-resistant rhabdomyosarcoma (RMS) models exhibit alterations in metabolic and genomic profiles Ariana Elizabeth Nelson, Abantika Chakraborty, David Bell, Victor J. Collins, Ali Mokhtar Mahmoud, Ying Wu, SOPHIA VARRIANO, Arnulfo Mendoza, Sameer Issaq, Parthav Jailwala, Jack F. Shern, Ernesto Suárez, Joseph Ivanic, Christine M. Heske
• 1799 · PDF Ferroportin mediates bevacizumab resistance and ferroptosis evasion in ovarian cancer Zonghao Tang, Amir A. Jazaeri, Weiche Wu, Mark Kim, Shannon N. Westin, Timothy A. Yap, Sanghoon Lee, Anil K. Sood
• 1800 · PDF Mitochondrial dysfunction induces asparaginase resistance in R-spondin fusion colorectal cancer Su Hyun Lee, Yun-Cheol Chae, Alejandro Gutierrez
• 1801 · PDF H. pylori infection induces WEE1 to promote drug resistance in gastric adenocarcinoma Md Obaidul Islam, Krishnapriya Thangaretnam, Jialun Lyu, Zhenzhen Zhang, Heng Lu, Dunfa Peng, Nadeem Sidiq Bhat, Mohammed Soutto, Wael El Rifai, Zheng Chen
• 1802 · PDF Fibroblast-driven tamoxifen resistance in ER+ breast cancer: Experimental validation and development of a high-throughput co-culture screening assay Elisabet Rodríguez-Tomàs, Francesco Massai, Arne Östman
• 1803 · PDF Dynamic copy number changes and de novo generation of extrachromosomal DNA modulate therapy resistance Tim Vorberg, Manuel Reitberger, Bernardo Rodriguez Martin, Maja Starostecka, Dominique Schulz, Arlou K. Angeles, Kate I. Glennon, Tasneem Cheytan, Roberto Würth, Vera Thiel, Paul Schwerd-Kleine, Verena Thewes, Laura Michel, Ewgenija Gutjahr, Simon J. Ogrodnik, Heike Conrad, Steffi O. Mehlhorn, Vanessa Vogel, Corinna Klein, Albrecht Stenzinger, Peter Lichter, Andreas Schneeweiss, Martin Granzow, Marc Zapatka, Anna Jauch, Holger Sültmann, Jan Korbel, Andreas Trumpp, Martin R. Sprick
• 1804 · PDF Midasin inhibition disrupts the sumoylation axis to impair mammosphere stability through alteration of transcriptional network Bipika Banjara, Mounika Pamukuntla, Manasa Kotina, Afia Ohemeng, Alicia Hudson, A. Michael Davidson, Jillian L. Pope, Selina F. Darling-Reed, Syreeta Tilghman
• 1805 · PDF Ancestry-dependent differences of PASK (Per-Arnt-Sim Kinase) inhibitor efficacy in triple-negative breast cancer under variable glucose conditions Ayomide Olayiwola, Sree Aramgam, K. Sean Kimbro
• 1806 · PDF WRN under the scalpel: Helicase-domain hotspot & splice-site knock-ins in HCT116 and RKO Yue Huang, Xiaomeng Gou, Jinying Ning, Feng Hao
• 1807 · PDF RLIP depletion suppresses ovarian cancer growth and metastasis Sharad S. Singhal, Madhu Krishna, Prakash Kulkarni, David Horne, Ravi Salgia
• 1808 METTL7A and METTL7B confer resistance to the oral thiol-based histone deacetylase inhibitor ST7612AA1 Omotola D. Gbadegesin, Robert W. Robey, Michael M. Gottesman
• 5291 · PDF EZH2-AR non-canonical axis activation in TKI-resistant RCC: Differential effects of lenvatinib and cabozantinib Christian Migliarese, Abbas Jawadwala, Sabrina A. Orsi, Stephanie Metcalf, Saranya Rajendran, Peter C. Hollenhorst, Roberto Pili

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