DNA Methylation

• 1949 · PDF Clonal expansion of leukocytes harboring mosaic chromosomal alterations accelerates epigenetic aging and reshapes local DNA methylation Corey D. Young, Charles Breeze, Derek W. Brown, Rebecca Lynn Kelly, Kara Marie Barnao, Aubrey K. Hubbard, Amy Hutchinson Hutchinson, BELYNDA HICKS, Aurélie L. Vogt, Wen-Yi Huang, Steven C. Moore, Stephen J. Chanock, Mitchell J. Machiela
• 1950 · PDF Integrated transcriptomic and epigenomic analysis to study the mechanism by which smoke-induced hypomethylation of cg05575921 increases lung cancer risk Matthew Gladstone, Khoi Huynh, Chunli Yan, Kimberly D. Siegmund, Aram Modrek, Ite Offringa
• 1951 · PDF Non-destructive methylation sequencing enables concurrent detection of genetic and epigenetic variation in FFPE and cfDNA samples Max Boeck, Jennifer Pavlica, Craig MARSHALL, Travis Sanders, Kristina Giorda, Martin Ranik, Eduard Casas, Thomas D. Harrison, Kailee Reed, Aaron Garnett, Doug Wendel, Brian Kudlow
• 1952 · PDF Novel mouse models enabling locus-specific manipulation of DNA methylation Julia M. Salamat, Li Yang, Xiaomin Chen, Eduardo Lopez, Lanlan Shen
• 1953 A novel synthetic lethal combination of FERMTs obtained by screening using DNA methylation-silenced genes Takahiro Ebata, Ryoma Mashiko, Yumi Furuichi, Qichun Wang, Yui Ohashi, Toshikazu Ushijima
• 1954 · PDF Spatial and single-cell DNA methylation analysis of primary breast cancer reveals lineage independent epigenetic plasticity Ruslan Strogantsev, Aysegul Ors, Jamie Endicott, Aaron R. Doe, Hugo Cros, Joseph Hwang, Hisham Mohammed
• 1955 · PDF Early-life gut microbiota programs intestinal stem cell epigenetics to protect against colon cancer later in life Li Yang, Shirui Zhou, Xiaomin Chen, Fabiola Gutierrez, Stephanie Fowler, Lanjing Zhang, Julia M. Salamat, Karen Riggins, Jiejun Shi, Lanlan Shen
• 1956 · PDF Efficacy of DNA methyltransferase inhibition in combination with immune-checkpoint/PARP-inhibitor in colorectal cancer preclinical model Pooja Mittal, Jae Ho Lo, Ben Yi Tew, Goar Smbatyan, Sandra Algaze, Lesly Torres Gonzalez, Unnati Hemant Shah, Michela Bartolini, Yan Yang, Steve Soto Trujillo, Wu Zhang, Josh Millstein, Gangning Liang, Bodour Salhia, Shivani Soni, Heinz Josef Lenz
• 1957 · PDF DNA methylation differentiates early-stage lung adenocarcinoma cells-of-origin with distinct smoking history and grade Xuan Cindy Li, Diego Almanza, Phuc Huu Hoang, Thi-Van-Trinh Tranh, Nicholas H. Juul, Maximilian Diehn, Tushar J. Desai, Maria Teresa Landi
• 1958 · PDF Targeting UHRF1-SUV39H1/H2 crosstalk enhances DNMT1 inhibitor efficacy in colon cancer Yanqing Liu, Joel A. Hrit, Alison A. Chomiak, Stephanie Stransky, Jordan Hoffman, Rochelle L. Tiedemann, Ashley K. Wiseman, Leena S. Kariapper, Bradley M. Dickson, Evan J. Worden, Christopher J. Fry, Simone Sidoli, Scott B. Rothbart
• 1959 · PDF The potential of methylated DNA markers for accurate detection of high-risk, HPV-positive cervical lesions Roshni Saravanan, Mary Jo Fackler, Madison Pleas, Wenfei Xia, Tomisin Adebari, Gang Yu, Liqun Zhang, Suzette Jordaan, Eunice Van Den Berg, Pamela Michelow, Reubina Wadee, Maureen Joffe, Wenlong Carl Chen, Youxiang Wang, Leslie Cope, Saraswati Sukumar
• 1960 · PDF The stability of epigenetic cell identity in cancer Cameron Cloud, Benjamin Steinberg, Yitzhak Reizel, Wanding Zhou
• 1961 · PDF DNA methylation signatures associated with tumor location in early-onset colorectal cancer identified across two independent cohorts Aniruddha B. Rathod, Sandi L. Pruitt, Amit G. Singal, Caitlin C. Murphy
• 1962 · PDF Epigenetic remodeling of BCOR-PRC1.1 complex dictates response and resistance to IDH inhibitors in AML Sarah Hanache, Xiaoyan Zhang, Satoko Ogata, Hidetaka Uryu, Ken Furudate, Zongrui Li, Abhinav Jain, Erika Thompson, Courtney D. Dinardo, Margaret A. Goodell, Koichi Takahashi
• 1963 · PDF The landscape of epigenetic alterations in the prostate cancer patient cohort from India Promit Ganguly, Tanay Biswas, Atin Singhai, Alok Srivastava, Abhishek Chauhan, Manzoor Ahmad, Piyush Tripathi, Sanjeev Mehrotra, Anjali Tewari, Nuzhat Husain, Apul Goel, Bushra Ateeq
• 1964 · PDF Age-related p16 epimutation is a targetable driver of Kras -mutant lung cancer Xiaomin Chen, Li Yang, Eduardo Lopez, Lili Ma, Chao Cheng, Lanjing Zhang, Lanlan Shen
• 1965 · PDF Conserved endothelial cell-specific DNA methylation alterations in colorectal and breast tumor microenvironments Barbara Karakyriakou, Ze Zhang, Lucas A. Salas Diaz, Brock C. Christensen
• 1966 · PDF Vitamin C delays mouse embryonic cells immortalization by maintaining enhancer hypomethylation of senescence-related genes Guillermo A. Urrutia, Minmin Liu, Rachel Shereda, Stacey L. Thomas, Gangning Liang, Peter A. Jones
• 1967 · PDF Methylation-based classification of circulating tumor DNA using enzymatic methyl-seq in a pan-cancer clinical cohort Kimberly A. Holden, Ashraf Shabaneh, Dennis D. Krutkin, Adib Shafi, Tong Liu, Kerry D. Fitzgerald, Eyad Almasri, Yuanyu Cao, Xiaojun Guan, Graham McLennan, Nathan Faulkner, Shakti Ramkissoon, Marcia Eisenberg, Brian Caveney, Eric Severson, Taylor J. Jensen, Jonathan Williams
• 1968 · PDF Epigenetic reprogramming via DNMT1 inhibition reduces invasion and migration in docetaxel-resistant prostate cancer Carmen M. Ortiz-Sanchez, Gabriela Castro, Shakira Abad, Solimar Esteves, Valerie Rodriguez, Stephanie Montalvo, Rodniel Aviles, Ralphdy Vergne, Gustavo Alayón, Caleb Santiago, Lenin Godoy, Kosj Yamoah, Gilberto Ruiz-Deya, Jong Y. Park
• 1969 · PDF Hypomethylating activity of zebularine suppresses migration in docetaxel-resistant prostate cancer cells Gabriela Castro Morales, Daniela Gonzalez, Gustavo Alayón, Ralphdy Vergne, Lenin Godoy, Jong Y. Park, Gilberto Ruiz-Deya, Carmen M. Ortiz-Sanchez
• 1970 · PDF Epigenetic modulation with 5-Azacytidine reduces aggressive phenotypes in 3D spheroid models of docetaxel-resistant prostate cancer Alanis Paola Torres Rosado, Gabriela Castro Morales, Lenin J. Godoy, Jong Y. Park, Gilberto Ruiz Deya, Carmen M. Ortiz-Sanchez
• 1971 · PDF Distinct genome wide DNA methylation signatures due to pathogenic germline variants in DKC1 , TERC , and TINF2 Kelvin César De Andrade, Gina Ney, Tianna Zhao, Shilpa Gaddam, Jia Liu, Kristine Jones, Lisa J. McReynolds, Neelam Giri, Sharon A. Savage

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