PO.CH02.02 · 化学
将多组学与AI驱动的方法整合到STEMM教育中以推进癌症研究培训
Integrating multi-omics and AI-driven approaches into STEMM education to advance cancer research training
作者与单位 Authors & Affiliations
摘要 Abstract
中文摘要
培养未来的科学家去应对癌症的复杂性,需要让他们尽早接触先进的分析方法和跨学科思维。我们开发了可扩展的STEMM教育项目,将多组学和人工智能整合到面向多个学习层次的癌症研究培训中。这一工作的核心是教师生物技术研究孵化器(Biotechnology Research Incubator for Teachers, BRITE),这是一项NIH R25科学教育合作奖(Science Education Partnership Award)项目,为中学教师提供植根于癌症生物学的实操多组学培训。通过纳入基因组学、蛋白质组学和数据驱动的解读,BRITE使教师能够将真实的癌症研究实践转化为课堂学习。在此基础上,由NCI资助的P20癌症研究教育项目(Cancer Research Education Program, C-REP)让本科生和研究生/PharmD学员参与多组学工作流程、肿瘤信号通路和计算分析。我们还建立了IMPACT医学学者项目(IMPACT Medical Scholar Program),向医学生介绍癌症研究方法、先进分析技术和以患者为中心的沟通。为了拓宽早期人才管道,我们创建了面向高中生的项目,采用AI辅助改编的原始文献,并以学生研究研讨会作为收尾。总体而言,这些项目提供了一个可扩展的模型,将先进技术整合到STEMM教育中,以加强对癌症研究的参与。
查看英文原文 English abstract
Preparing future scientists to address the complexity of cancer requires early exposure to advanced analytical methods and transdisciplinary thinking. We developed scalable STEMM education programs that integrate multi-omics and artificial intelligence into cancer research training across multiple learner levels. Central to this effort is the Biotechnology Research Incubator for Teachers (BRITE), an NIH R25 Science Education Partnership Award program providing secondary-school teachers with hands-on multi-omics training rooted in cancer biology. By incorporating genomics, proteomics, and data-driven interpretation, BRITE equips teachers to translate authentic cancer research practices into classroom learning. Building on this foundation, the NCI-funded P20 Cancer Research Education Program (C-REP) engages undergraduate and graduate/PharmD trainees in multi-omics workflows, tumor signaling pathways, and computational analyses. We also established the IMPACT Medical Scholar Program, which introduces medical students to cancer research methodologies, advanced analytics, and patient-centered communication. To broaden the early pipeline, we created high-school programs that use AI-assisted adapted primary literature and culminate in a student research symposium. Collectively, these programs provide a scalable model for integrating advanced technologies into STEMM education to strengthen participation in cancer research.
利益披露 Disclosure
S. Huang, None.