PO.CH02.02 · 化学
Multi-Omics, Systems Biology, and Biological Mass Spectrometry
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7647 · PDF 生态型指导的多组学分析鉴定胃癌中潜在的细胞表面治疗靶点 Ecotype-guided multi-omics profiling identifies potential cell-surface therapeutic targets in gastric cancer Yuefan Wang, Lindsey K. Olsen, Hui Zhang, Bing Zhang, Clinical Proteomic Tumor Analysis Consortium (CPTAC)
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7648 · PDF 血浆蛋白-转录组整合鉴定室管膜瘤中的分子特征和循环生物标志物 Plasma proteo-transcriptomic integration identifies molecular signatures and circulating biomarkers in ependymomas Rafat Malik, Ritu Kulshreshtha, Amandeep Kumar, Vaishali Suri, Mehar Chand Sharma
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7649 · PDF 尿砷形态分析与代谢指数与暴露化学特征及前列腺癌侵袭性相关 Urinary arsenic speciation and metabolic indices associate with exposure chemistry and prostate cancer aggressiveness Sithembiso S. Msibi, MinJae Lee, Ping-Ching Hsu, L. Joseph Su
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7650 · PDF 利用单分子蛋白质测序高分辨率检测翻译后修饰 High-resolution detection of post-translational modifications using single-molecule protein sequencing Natchanon Sittipongpittaya, Khanh (Kendrick) Dinh Quoc Nguyen, Andrey Reshetnyak, Muriel Priault, Ajay Vashisht, John Vieceli, Meredith Carpenter, Nidhi Sahni, Gloria Sheynkman
- 7652 7652 双向蛋白质基因组学识别三阴性乳腺癌中肿瘤特异性、免疫可见的肽段用于免疫治疗开发 Two-way proteogenomics identifies tumor-specific, immune-visible peptides for immunotherapy development in triple-negative breast cancer Moran Chen, Jong Min Choi, Zhiao Shi, Wenrong Chen, Bing Zhang
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7653 · PDF POU2F3转录因子驱动的小细胞肺癌中的新治疗机会 Novel therapeutic opportunities in POU2F3 transcription factor-driven small cell lung cancer Lily L. R. Rix, Hayley D. Ackerman, Nicole R. Hackel, Xueli Li, Rachel Leigh O'Rourke, Juhyeon Son, Michelle A. Reiser, Arianna Nenci, Bin Fang, Eric A. Welsh, Brandon J. C. Klein, John M. Koomen, Eric B. Haura, Florian Karreth, Amanda Garner, Elsa R. Flores, Uwe Rix
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7654 · PDF 子宫内膜癌中超高频突变体PTEN R130G的独特致癌机制 Unique oncogenic mechanisms of ultrahigh-frequency mutant PTEN R 130G in endometrial cancer Xiangyi Kong, Li Wang, Md Kamrul Hasan Khan, Jidong Wang, Huaijun Zhou, Xinyan Wu
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7655 · PDF 利用串联质谱和离子-离子反应定义糖-免疫检查点配体的分子界面 Defining molecular interfaces of glyco-immune checkpoint ligands using tandem mass spectrometry and ion-ion reactions Tim S. Veth, Haley M. Schramm, Nicholas M. Riley
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7656 · PDF 癌前病变和结直肠癌患者粪便宏蛋白质组的全面研究 Comprehensive investigation of stool metaproteomes among patients with precancerous lesions and colorectal cancer Emmalee J. Northrop-Albrecht, Vinod K. Gupta, William R. Taylor, Jason P. Sinnwell, Doug W. Mahoney, Patrick H. Foote, Kelli N. Burger, Jaeyun Sung, John B. Kisiel
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7657 · PDF 一种AFA辅助的FFPE样本基于质谱的蛋白质组学工作流程 An AFA assisted workflow for mass-spectrometry based proteomics of FFPE samples Dong-Gi Mun, Kiran Mangalaparthi, Daigo Gunji, Amy J. French, Raghavendra Pasupuleti, Cristine Charlesworth, Sameer Vasantgadkar, DEB BHATTACHARYYA, Akhilesh Pandey
- 7658 7658 绘制FGFR1-4上突变特异性的相互作用与信号网络,以理解癌症相关的重连 Mapping mutation-specific interaction and signalling networks across FGFR1-4 to understand cancer-associated rewiring Iftekhar Mahmud Chowdhury, Xiaonan Liu, Markku Varjosalo
- 7660 7660 细胞表面N-糖基化改变提示高唾液酸化参与乳腺癌脑转移 Altered cell surface N-glycosylation implicates hypersialylation in breast cancer brain metastasis Judith Nwaiwu, Wenjing Peng, Akhila Reddy, Xue Dong, Parisa Ahmadi, Jingfu Zhao, Yifan Huang, Peilin Jiang, Waziha Purba, Oluwatosin Daramola, Yehia Mechref
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7661 · PDF 使用nCounter®蛋白和RNA面板对裂解物进行整合多组学分析,以获得全面的肿瘤学见解 Integrated multiomics profiling of lysates using nCounter® protein and RNA panels for comprehensive oncology insights Brian Filanoski, Lori Hamanishi, Giang Ong, Terence C. Theisen, Erin Piazza, Christina Bailey, Prajan Divakar, Margaret L. Hoang, Joseph M. Beechem
- 7662 7662 由ZEISS slide stream和Vizgen InSituPlex®检测实现的用于空间生物学的高通量、自动化、可重现mIF工作流程 A high-throughput, automated, and reproducible mIF workflow for spatial biology enabled by ZEISS slide stream and Vizgen's InSituPlex® assays Cassandra Kysilovsky, Kevin Hwang, Susanne Pfeifenbring, Michael Downing, Sherry Derakhshani, Moritz Widmaier, Jiang He, Angela Vasaturo
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7663 · PDF 利用基于质谱的免疫肽组学在癌症组织样本中发现肿瘤特异性肽和新抗原肽 Discovery of tumor-specific and neoantigenic peptides in cancer tissue samples using mass spectrometry-based immunopeptidomic Cameron Ellis, Arhur Viodé, Anamarija Pfeiffer, Lucy Yang, Monika Pepelnjak, George Rosenberger, Polina Shichkova, Kristina Marx, Christopher Below, Roland Bruderer
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7664 · PDF 用于从细胞和组织进行全面多组学分析的自动化顺序蛋白质/DNA/RNA提取工作流程 An automated sequential protein/DNA/RNA extraction workflow for comprehensive multiomics analysis from cells and tissue Laure Jobert, Charmaine Hinahon, Leigh Foster, Marie Holter-Sørensen, Samri Michael, Iwona Grad, Lina Zheng, Berit Reed
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7665 · PDF 用于nCounter高重数多组学面板的多步骤抗体验证 Multi-step antibody validation for nCounter high-plex multiomics panels Giang Ong, Terence C. Theisen, Brian Filanoski, Lori Hamanishi, Erin Piazza, Christina Bailey, Prajan Divakar, Margaret L. Hoang, Joseph M. Beechem
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7666 · PDF 全面的表面组分析揭示骨肉瘤中的肿瘤特异性靶点 Comprehensive surfaceome profiling reveals tumor specific targets in osteosarcoma Snehal D. Ganjave, Kevin K. Leung, Leanne C. Sayles, Alejandro Sweet-Cordero, James A. Wells
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7667 · PDF 将多组学与AI驱动的方法整合到STEMM教育中以推进癌症研究培训 Integrating multi-omics and AI-driven approaches into STEMM education to advance cancer research training Shixia Huang
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7668 · PDF 来自pks+ NC101和pks- DH10B大肠杆菌菌株的外膜囊泡(OMVs)的表征 Characterization of outer membrane vesicles (OMVs) from pks+ NC101 and pks- DH10B E. coli strands Lissette Marie Perez-Rovira, Grace Enid Velez Crespo, Luis A. Prieto-Costas, Jeremy J. Colon-Morales, Abel Baerga-Ortiz
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7669 · PDF 使用自动化检测工作站对人细胞因子和自身抗体进行自动化多重分析 Automated multiplex profiling of human cytokines and autoantibodies using an Automated Assay Workstation Wen-Rong Lie, Brooke Gilliam, Laura Marquardt, Mark Pawlicki, Ernest Mueller, Xiuyuan Zhang, Nathanael Ellis, Todd Hendrich, Linda Meeh, Scott Keefer, Qiang Xiao
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7670 · PDF 整合的质谱工作流程助力癌症研究中的下一代偶联疗法 Integrated mass spectrometric workflows enabling next-generation conjugate therapeutics in cancer research Min Fang, Nilesh Sonawane, Wenchuan Ma, Benjamin Wei, Qingcong Lin
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7671 · PDF 用于精准肿瘤学的原代类肿瘤模型的整合蛋白质基因组学 Integrated proteogenomics of primary tumoroid models for precision oncology Shawn P. Fahl, Audrey Kleeman, Jessica Maxwell, Yukta Bhurke, Jessica Moore, Jaison Arivalagan, Kerri Colwell, Cavin Ott, Kayla Williams, Danielle Gutierrez
- 7672 7672 使用HCR™ Gold IF和临床相关抗体克隆进行自动化、灵活的多重免疫荧光肿瘤微环境分析 Automated, flexible multiplex immunofluorescence for tumor microenvironment profiling using HCR™ Gold IF and clinically-relevant antibody clones Wudy Yang, Randy Chen, Harry Choi, Aneesh Acharya, Anne Hellebust, Will Howat
- 7673 7673 使用HCR™ Gold和MoxiePlex在FFPE肿瘤中对临床相关的蛋白和RNA靶标进行9通道空间共检测 9-channel spatial co-detection of clinically relevant protein and RNA targets in FFPE tumors with HCR™ Gold and MoxiePlex Wudy Yang, Randy Chen, Harry Choi, Aneesh Acharya, Minakshi Singh, Quyen Vu
- 7674 7674 用于安全、可扩展和灵活的单细胞多组学研究的无甲醛固定 Formaldehyde-free fixation for safe, scalable and flexible single-cell multiomics studies Joseph Olives, Hongduan Huang, Zhiqi Zhang, Lin Chen, Rosary Nguyen, Hye-won Song, Aruna Ayer