Liquid Biopsies: Circulating Nucleic Acids 3

• 3840 · PDF 通过循环肿瘤DNA分析检测结直肠癌患者术后的微小残留病灶 Detection of minimal residual disease in colorectal cancer patients after surgery through circulating tumor DNA profiling Luis Maya Janssen, Ekaly Apagnha, Flávio de Alencar Teles Barreto, André Araújo de Medeiros Silva, Mayra Veloso Ayrimoraes Soares, João Batista de Sousa, Fabio Pittella-Silva
• 3841 · PDF 通过ctDNA测序识别的PI3K-AKT通路改变在转移性去势抵抗性前列腺癌中的预后意义 Prognostic significance of PI3K-AKT pathway alterations identified by ctDNA sequencing in metastatic castration-resistant prostate cancer DongSoo Kyung, Yongjun Cha, Chang Wook Jeong, Seung-hwan Jeong, Chel Lee, Won Yeong Ko, Jee-Soo Lee, Moon-Woo Seong, Cheol Kwak, Tae-You Kim
• 3842 3842 无创cfDNA甲基化分析用于预测NSCLC中PD-L1肿瘤比例评分状态 Non-invasive cfDNA methylation profiling for prediction of PD-L1 tumor proportion score status in NSCLC Wei Tian, Anton Valouev, Kunwar Singh, Matthew Ellis, Katie Quinn, Tingting Jiang, Martina Lefterova, Justin Odegaard, Darya Chudova
• 3843 · PDF 对乳腺癌患者全血中全长mRNA进行测序以选择抗体药物偶联物治疗 Sequencing full-length mRNA in whole blood of breast cancer patients for antibody-drug conjugate therapy selection Jacob Bradley, Gabriel Benitez, Mark Barnett, Oliver Eve, Ivalya Ivanova, Katrina Morris, Alice Séguret, Ahmad Zyoud, John Davey, Yuanyuan Cheng, Amy Robinson, Arran Turnbull, Mike Dixon, Han-Yu Chuang, Rick Hockett, Richard Kuo, Pamela N. Munster
• 3844 · PDF 采用高度多重化USE-PCR并整合定制靶点对黑色素瘤进行纵向ctDNA监测，可实时检测治疗反应与复发 Longitudinal ctDNA monitoring in melanoma using highly multiplexed USE-PCR incorporating bespoke targets enables real-time detection of treatment response and recurrence Hunter Miller, Annalara Fischer, Melissa Hall, Michael E. Egger, Kavitha Yaddanapudi, Lucien Jacky, John Alvarado, Aaron Aguiar, Nathaniel Clark, Paul Belitz, Jeremy Myslinski, Jerrod Schwartz, Paul Flook, Mark Linder
• 3845 · PDF 通过超灵敏ctDNA检测增强MRD检出：来自真实世界临床数据的见解 Enhancing MRD detection through an ultrasensitive ctDNA test: Insights from real-world clinical data Rachel Marty Pyke, Steven Dea, Sherif El-Refai, Fábio C. P. Navarro, Charles W. Abbott, Yi Chen, Janet Lai, Gabor Bartha, John M. Lyle, Jason Harris, Vijay Gunuganti, Sean M. Boyle, Richard O. Chen
• 3846 · PDF 短双链cfDNA：一类用于癌症诊断的新型精准生物标志物 Short double-stranded cfDNA: A novel precision biomarker class for cancer diagnostics Mirko Sonntag, Zhoutao Zhang, Denise Leupold, Jan Mueller, Yevhen Vainshtein, Christina Hartwig, Georg F. Weber, Kai Sohn
• 3848 · PDF 基于尿液游离DNA甲基化的去卷积在局限性泌尿道癌症中鉴定肿瘤特异性细胞类型 Urine cell-free DNA methylation-based deconvolution identifies tumor-specific cell types in localized urinary tract cancers Ze Zhang, Rashad Nawfal, Gunsagar Gulati, Damien Vasseur, Ji-Heui Seo, Hunter Savignano, Razane El Hajj Chehade, Karl Semaan, Tamara Merhej, John Canniff, Noa Phillips, Ning Shen, Phillip Adams, Ilana Epstein, Jack Horst, Alexis Zinselmeier, Rachel Throwbridge, Gwo-Shu Mary Lee, Jamil Azzi, Michelle S. Hirsch, Martin Kathrins, Timothy N. Clinton, Matthew Mossanen, Keegan Korthauer, Toni K. Choueiri, Matthew L. Freedman, Sylvan C. Baca
• 3849 · PDF 使用mDETECT液体活检对NSCLC免疫治疗进行频繁监测，揭示意料之外的复杂性与机遇 Frequent monitoring of NSCLC immunotherapy using an mDETECT liquid biopsy reveals unexpected complexity and opportunities Mihaela Mates, Andrew Robinson, Harriet Feilotter, Sofia Genta, Keira Frosst, Keira Parr, Garrett Baron, Christopher R. Mueller
• 3850 · PDF 基于液体活检监测HPV阳性口咽癌（OPSCC）患者的疾病状态 Liquid biopsy-based monitoring of disease status in patients with HPV-positive oropharyngeal carcinoma (OPSCC) Jens Peter Klussmann, Oliver Siefer, Zurwa Merrjam Uzun, Jannik Johannsen, Dustin Firmenich, Nora Wuerdemann, Ernst J.M. Speel, Julie George
• 3851 · PDF 超灵敏ctDNA监测预测复发性转移性非小细胞肺癌免疫治疗的早期反应 Ultrasensitive ctDNA monitoring predicts early response of immunotherapy in recurrent metastatic non-small cell lung cancer Kishen R. Patel, Bailiang Li, Charles W. Abbott, Cristina Naceur-Lombardelli, Sadegh Saghafina, Sevasti Galani, James R. M. Black, Wing Liu, Nicola Steele, Gillian Price, Shobhit Baijal, Dean Fennell, Matthew G. Krebs, Tanya Ahmad, Alexandra Pender, Siow M. Lee, Mariam Jamal-Hanjani, Nicholas McGranahan, Allan Hackshaw, Sean Michael Boyle, Richard O. Chen, Charles Swanton, Crispin T. Hiley
• 3852 · PDF 基于多维cfDNA特征的超灵敏AI驱动MRD检测框架 Ultrasensitive AI-driven framework for MRD detection based on multidimensional cfDNA features Yunfei Shi, Hao Zhang, Zexiao Lin, Ningyou Li, Maolong Wang, Hua Bao, Jinfeng Zhang, Zhili Chang, Yong Ge, Peng Li, Pan Wang, Liang Huang, Xiangming Liu, Lu Han, Wangming Ji, Teng Sun, Dujun Hua, Xunbiao Liu, Mingya Wang, Baihan Zhu, Dongqin Zhu, Xue Wu, Haimeng Tang, Hao Zhang, Yang Shao
• 3853 · PDF 亚洲子宫内膜癌循环肿瘤DNA的基因组分析：A-TRAIN研究 Genomic profiling of circulating tumor DNA in endometrial cancer in Asia: A-TRAIN study Hiroki Tamura, Yuki Kojima, Kazuki Sudo, Wan Zamaniah Wan Ishak, Marcelo S. Imasa, Arb-aroon Lertkhachonsuk, Ryoka Miki, Hiroshi Yoshida, Shinji Kohsaka, Yukari Nagasaka, Ryunosuke Machida, Tetsuya Sasaki, Tomomi Hata, Kenichi Nakamura, Kan Yonemori
• 3854 · PDF 血浆游离RNA转录组分析揭示胰腺导管腺癌的转录失调与免疫重塑 Plasma cell-free RNA transcriptome analysis reveals transcriptional dysregulation and immune remodeling in pancreatic ductal adenocarcinoma Gyuryang Park, Hyosil Kim, Tae Young Kim, Sung Joon Kim, Jin-Hwa Park, Baeki E. Kang, Jung Won Chun, Sung-Sik Han, Tae Min Kim, Sang Myung Woo
• 3855 3855 循环DNA甲基化特征可实现胃肠道癌症的早期检测 Circulating DNA methylation signatures enable early detection of gastrointestinal cancers Ruo-Kai Lin, YAO-YU HSIEH
• 3856 · PDF 检测晚期癌前病变的cfDNA释放 Detection of cfDNA shedding from advanced precancerous lesions Fei Lu, Liliana Cerna, Spenser Alexander, Noura Tbeileh, Esha Atolia, Dina Hafez, Eser Kirkizlar, Matthew Rabinowitz, Alexey Aleshin, Trupti Kawli
• 3857 · PDF 血液中循环肿瘤DNA的全面分析可实现HPV癌症及癌前病变的灵敏检测和基因组特征描述 Comprehensive profiling of circulating tumor DNA in blood enables sensitive detection and genomic characterization of HPV cancer and precancer Qin Wang, Samuli Eldorfs, Sangmi Sandra Lee, Yana Al-Inaya, Gjystina Lumaj, Eliana Epstein, Dipon Das, Emma Ricart, Harsharan Dhillon, Juniper Lake, Michael G. Drage, Shun Hirayama, Viktor Adalsteinsson, Benjamin T. Davis, Doga C. Gulhan, Daniel Faden
• 3858 · PDF 使用EMSeq全基因组测序和靶向甲基化组panel对游离DNA进行甲基化分析以对儿童眼部和脑部肿瘤进行分类 Methylation profiling of cell free DNA using EMSeq whole genome sequencing and a targeted methylome panel for classification of pediatric ocular and brain tumors Laura A. T. Kagami, David N. Buckley, Jesse L. Berry, Susan N. Chi, Xiaowu Gai, Erin Kiehna, Katrina O’Hollaran, Dejerianne Ostrow, Tom Rosenberg, Yan Chen Wongworawat, Liya Xu, Jaclyn Biegel
• 3859 · PDF 使用靶向α发射体212Pb-DOTAMTATE AlphaMedix治疗的转移性神经内分泌肿瘤（NET）患者的动态全身免疫调节 Dynamic systemic immune modulation in metastatic neuroendocrine tumor (NET) patients treated with targeted alpha-emitter 212 Pb-DOTAMTATE AlphaMedix Alessandra Jordano Conforte, Izabela Tworowska, Sara Fonseca Costa, Marta Brzezinska, Amaia Martinez Usatorres, Noushin Hadadi, Sylvain Monnier-Benoit, Simona Pavan, Rouzbeh Esfandiari, Brian Hashemi, Pedro Romero, Ebrahim S. Delpassand
• 3860 · PDF 一种使用定量甲基化特异性PCR在cfDNA中进行多癌种检测的低成本生物检测 A low-cost bioassay for multi-cancer detection in cfDNA using quantitative methylation-specific PCR Emily Neaga, Sarah Falotico, Mayur Gurnani, Miguel Williams, Anthony Shuber
• 3861 · PDF 利用甲基化特异性定量PCR低成本检测cfDNA中的进展期腺瘤 Low-cost detection of advanced adenomas in cfDNA using quantitative methylation-specific PCR Emily Neaga, Sarah Falotico, Mayur Gurnani, Miguel Williams, Anthony Shuber
• 3862 · PDF 趋同性染色质重塑实现血浆cfDNA中泛消化道恶性肿瘤晚期病变的检测 Convergent chromatin remodeling enables pan-aerodigestive detection of advanced malignancies in plasma cfDNA Axel Misael Hidalgo, Ayesha Hashmi, Jeff Szymanski, Pradeep Chauhan, Lilli Greiner, Faridi Qaium, Daniel J. Ma, David M. Routman, Katie M. Van Abel, Aadel A. Chaudhuri
• 3863 · PDF 在Ultima Genomics平台上基于cfDNA片段化的增强型治疗监测 Enhanced cfDNA fragmentation-based treatment monitoring on the Ultima Genomics platform Laurel K. Millberg, Garrett Graham, Zachary Skidmore, Jordan Gumm, Kevin Jacobs, Ariel Jaimovich, Elena Helman, Bryan Chesnick, Roberto Olivares-Amaya, Timothy Mcdaniel, Sian Jones, Amoolya Singh, Lorenzo Rinaldi
• 3864 · PDF 使用超灵敏的肿瘤指导型结构变异检测方法对转移性乳腺癌进行连续ctDNA监测 Serial ctDNA monitoring in metastatic breast cancer using an ultrasensitive tumor informed structural variant based assay Mitchell J. Elliott, June Roh, Kareena Thakur, Sasha Main, Karen Howarth, Sofia Birkeälv, Jennifer Yen, Völundur Hafstad, Wendy Levin, Vikash Kumar, Long Nguyen, Meredith Li, Scott Victor Bratman, Eitan Amir, Philippe L. Bedard, Lillian L. Siu, Hal Berman, David Cescon

在会议检索中浏览本分会场