PO.ET02.13 · 实验与分子治疗
Hematologic Malignancies and Novel Therapeutic Modalities
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- 4514 4514 用于测定AML患者全血中AML原始细胞群磷酸化蛋白的CyTOF检测方法的开发与验证 Development and validation of a CyTOF assay for measuring phosphoproteins in AML blast cell populations in whole blood from AML patients Steven R. Pirie-Shepherd, Crystal Tarrago, Wenxin Zheng, Sen Zhang, Hamish Wright
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- 4517 4517 氨苯蝶啶作为分子胶抑制NRF2 Mut Triamterene inhibits NRF2 Mut as a molecular glue Yahui Li, Zachary Ladd, Haining Wang, Candice Bui-Linh, Boopathi Subramaniyan, Chorlada Paiboonrungruang, Huan Li, Yan Ma, Kiera Chang, Katherine Gao, Maiya Ang, Francis Spitz, Zhaohui Xiong, Xiaoxin Luke Chen
- 4518 4518 BT5528在胰腺导管腺癌（PDAC）患者来源异种移植（PDX）模型中抗肿瘤活性的临床前评估 Preclinical assessment of BT5528 anti-tumor activity in patient-derived xenograft (PDX) models of pancreatic ductal adenocarcinoma (PDAC) Lukas Stanczuk, Assunta De Rienzo, Gavin Bennett
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- 4521 4521 利用p120 RasGAP分子胶抑制NF1缺失细胞中的KRas Use of a p120 RasGAP glue to inhibit KRas in NF1-null cells Anastasiia Gerasimova, Sven Miller, Jonathan Chernoff
- 4522 4522 通过AcroAIxTM推进蛋白质工程：以AI驱动的策略优化结构与功能 Advancing protein engineering through AcroAIxTM: AI-driven strategies for enhanced structure and function optimization Spencer Chiang, Jane Liu, Lisa Chou, An Ouyang, Lili Qin
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- 4528 4528 基底细胞来源的基质细胞蛋白SPON2通过阻断SLC38A1/mTOR代谢轴抑制腔上皮细胞的氧化磷酸化和癌症进展 The basal cell-derived matricellular protein SPON2 suppresses luminal cell oxidative phosphorylation and cancer progression by blocking the SLC38A1/mTOR metabolic axis Pengfei (Paul) Lu
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