PO.MCB02.01 · 分子与细胞生物学
Cell Death Regulation and Therapeutic Resistance in Cancer
- 4652 4652 解析中性粒细胞异质性以增强TRAIL(肿瘤坏死因子相关凋亡诱导配体)在三阴性乳腺癌中的治疗疗效 Deciphering neutrophil heterogeneity to enhance therapeutic efficacy of TRAIL (Tumor necrosis factor-related apoptosis-inducing ligand) in triple negative breast cancers Manjari Kundu Sil, Dinesh Kumar, Wenqi Wu, Lichun Ma, Stan Lipkowitz
- 4653 4653 TC-PTP介导的p38 MAPK信号调控在UVB照射下诱导表皮细胞凋亡 TC-PTP-mediated regulation of p38 MAPK signaling induces epidermal apoptosis in response to UVB irradiation Rodrigo Vidales, Lindsey Shim, Subhash Chauhan, Dae Joon Kim
- 4654 4654 Leptospermum petersonii甲醇和乙酸乙酯粗提物对胰腺癌和前列腺癌细胞的抗转移及促凋亡作用 Leptospermum petersonii methanol and ethyl acetate crude extracts as antimetastatic and apoptotic effects against pancreatic and prostate cancer cells Lesetja Motadi, Maria Matlou
-
4655 · PDF 迷迭香酸抑制乳腺癌细胞增殖并诱导凋亡 Carnosic acid inhibits proliferation and induces apoptosis of breast cancer cells Amanda L. Kornel, Evangelia Tsiani
- 4656 4656 一种靶向FOLR1和TRAIL-R2的新型双特异性抗体用于治疗卵巢癌 A Novel FOLR1 and TRAIL-R2 targeting bispecific antibody to treat ovarian cancer Shiva Bhowmik, William Brady
-
4657 · PDF 抗原性癌症持留细胞可在T细胞的直接攻击下存活 Antigenic cancer persister cells survive direct T cell attack Brandon E. Mauch, Michael Wang, August (Gus) Finley Williams, Tania Barazande-Pour, Filipe Araujo-Hoffman, Sophie Harris, Cooper Lathrop, Matthew Hangauer
- 4658 4658 新型Bcl-2/Bcl-xL抑制剂LP-118增强CDK2/9抑制剂fadraciclib在BRAF(V600E)人结直肠癌细胞中的凋亡诱导作用 Novel Bcl-2/Bcl-xL inhibitor, LP-118, enhances apoptosis induction by the CDK2/9 inhibitor, fadraciclib, in BRAF(V600E) human colorectal cancer cells Md Mohiuddin, Vanda Póvoa, Beatriz Sebo, Rita Fior, Frank A. Sinicrope
-
4660 · PDF Mcl-1抑制剂与抗抑郁药作为胸膜间皮瘤化疗反应的增强剂 Mcl-1 inhibitors and antidepressants as enhancers of chemotherapy response in pleural mesothelioma Francisco A. Molina-Pelayo, Cristian G. Medina, Jaylon C. Aggison, Naren Li, Siqi Wu, Hainin Yang, Michele Carbone, Yuan Xu, Robert T. Ripley
- 4661 4661 铁死亡抑制因子FSP1(而非GPX4)的表达在TP53野生型弥漫大B细胞淋巴瘤中显示出显著的不良预后效应 Expression of the ferroptosis suppressor FSP1 but not GPX4 shows significant adverse prognostic effect in diffuse large B-cell lymphoma with wild-type TP53 Beibei Lyu, Zijun Xu-Monette, Xiaoxian X. Zhao, Eric D. Hsi, Ming Chen, Carlo Visco, Alexandar Tzankov, Karen Dybkaer, Mu-En Wang, Chang Wang, Qingyan Au, Harry Nunns, Zenggang Pan, Benjamin Parsons, Santiago Montes-Moreno, Fenghuang Zhan, Michael B. Møller, Leon Bernal-Mizrachi, Youli Zu, Shanxiang Zhang, Weina Chen, Govind Bhagat, Yong Li, KEN H. YOUNG
-
4662 · PDF 线粒体抗氧化剂mitoquinone改变癌细胞对治疗的死亡结局 The mitochondrial antioxidant mitoquinone alters cancer cell death outcomes in response to therapy Christopher W. Clark, Xingping Qin, Cameron Fraser, Jessalyn Ubellacker, Kristopher A. Sarosiek
- 4663 4663 BGB-21447,一种新一代Bcl-2抑制剂,在血液系统恶性肿瘤临床前模型中展现出更优效力并克服Venetoclax耐药 BGB-21447, a next-generation Bcl-2 inhibitor, demonstrates superior potency and overcomes Venetoclax resistance in preclinical models of hematologic malignancies Shuran Li, Shasha Yang, Xiaolong Yang, Yanwen Ma, Shining Nie, Longbo Yin, Qin Wang, Haimei Xing, Zhu Mei, Ali Wang, Xiaolin Liu, Ying Guo, Haitao Wang, Weiwei Song, Lin Li, Lu Lyu, Yiwen Wang, Jin Wei, Chuanxiu Wang, Ye Liu, Xi Yuan, Yunhang Guo, Yu Shen, Lai Wang, Xiaomin Song
-
4664 · PDF 内皮细胞自噬抑制对肿瘤发生的影响 Impacts of endothelial cell autophagy inhibition on tumorigenesis Nancy Esmeralda Leon-Rivera, Brayden Chin, Teresa Monkkonen
-
4665 · PDF 可编程多价siRNA纳米结构通过共沉默MCL-1和BCL-XL重塑胶质母细胞瘤的凋亡 Programmable multivalent siRNA nanostructure rewires apoptosis by co-silencing MCL-1 and BCL-XL in glioblastoma Qianhui Feng, Henry Lin, Yichen Yan, Rong Zheng, Yang Xu, Hao Yan
- 4666 4666 CAPZB通过与SQOR相互作用抑制disulfidptosis(二硫化物死亡),驱动肝内胆管癌进展并带来治疗脆弱性 CAPZB suppresses disulfidptosis through SQOR interaction to drive intrahepatic cholangiocarcinoma progression and therapeutic vulnerability Jiangqiao Yao, Tong Chen, Ziyan Chen, Gang Chen, Chongming Zheng, Yi Wang
-
4667 · PDF 靶向ULK1克服癌细胞中自噬介导的化疗耐药 Targeting ULK1 overcomes autophagy-mediated chemoresistance in cancer cell Eun-Jung Kim, Youngjun Park
-
4668 · PDF 靶向组蛋白乙酰转移酶GCN5使癌细胞对铁死亡敏感 Targeting the histone acetyltransferase GCN5 sensitizes cancer cells to ferroptosis Ling-Chu Chang, Shih-Kai Chiang, Shuen-Ei Chen
- 4669 4669 通过全息断层成像与深度学习无标记识别癌细胞死亡通路作为早期药效学生物标志物 Label free identification of cancer cell death pathways via holotomography and deep learning as an early pharmacodynamic biomarker Minwook Kim, Park Weisun, Geon Kim, Sanggeun Oh, Juyeon Park, Jihwan Yu, Hyun-Suk Min, Sumin Lee, Won Do Heo, YongKeun Park
-
4670 · PDF CtBP1/KAISO/TRIM28复合物对乳腺癌细胞自噬的多模式机制调控 Multimodal mechanistic control of autophagy by the CtBP1/KAISO/TRIM28 Complex in breast cancer cells Young-Ho Lee, Kevin L. Gardner
-
4671 · PDF PRMT5抑制后KRAS突变型结直肠癌中的自噬改变 Autophagy alterations in KRAS-mutant colorectal cancer following PRMT5 inhibition Komalpreet Kaur, Danbee Chae, Daniel Aguaiza, Netanel Louloueian, Shloimie Lowy, SANJAY GOEL, Radhashree Maitra
-
4672 · PDF 神经肽Y Y1受体抑制诱导自噬以限制结直肠癌进展 Neuropeptide Y Y1 receptor inhibition induces autophagy to limit colorectal cancer progression Sooraj Kakkat, Prabhat Suman, Aris Richter, Steven B McClellan, Debanjan Chakroborty, Chandrani Sarkar
-
4673 · PDF 靶向BCL2通路以增强ALK+ NSCLC的免疫原性 Targeting BCL2 pathway to enhance immunogenicity in ALK + NSCLC Batkhishig Munkhjargal, Sudha Mudumana Sadasivan, Shirish M. Gadgeel, Amanda Pilling
-
4674 · PDF 叶酸受体alpha激活STAT3/LATS1信号轴使乳腺癌细胞抵抗铁死亡 Activation of a STAT3/LATS1 signaling axis by folate receptor alpha enables breast cancer cells to resist ferroptosis Prajakta Prasad Ambegaokar, Hira Goel, Arthur M. Mercurio
-
4675 · PDF 整合实时阻抗与荧光成像以表征NETosis Integrated real-time impedance and fluorescence imaging to characterize NETosis Tian Wang, Xiaoyu Zhang, Grace Yang, Peifang Ye, Nancy Li
-
4676 · PDF AUTAC在血液系统恶性肿瘤中的治疗性应用及心脏保护作用 Therapeutic exploitation of AUTAC in hematologic malignancies with cardiac protection Ahmed M. Elshazly, Nayyerehalsadat Hosseini, Senthil K. Radhakrishnan
-
4677 · PDF 雌激素通过破坏有丝分裂纺锤体组装诱导非生殖系统癌细胞死亡 Estrogen induces cell death in non- reproductive cancer cells through disrupting mitotic spindle assembly Pu Liang, Song Zeng, Wei Chen, Dong Li, Wei Feng, Xiaopeng Hu, Wensheng Wei, Xin Liang, Xi Wang