PO.TB10.18 · 肿瘤生物学
Novel Experimental Platforms and Causal Inference
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- 4915 4915 利用功能性CRISPR筛选研究肺鳞状细胞癌过继性T细胞疗法中的代谢基因 Using functional CRISPR screening to investigate metabolic genes in lung squamous cell carcinoma adoptive T cell therapy Verra Ngwa, Jin Chen
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- 4919 4919 利用患者来源类器官的空间和细胞类型特异性分析解码NF1肿瘤的肿瘤微环境 Decoding the tumor microenvironment of NF1 tumors using spatial and cell-type specific analyses of patient-derived organoids Alberto Mendoza-Valderrey, Michael J. Lippincott, Huyen Thi Lam Nguyen, Jenna Tomkinson, Cameron Mattson, Dave Bunten, Summer Norris, Jeremy Jacobson, Jackson Chin, Paul Piehowski, Le Day, Chelsea Hutchinson Bunch, Christopher Anderton, Brittney Gorman, Sara Gosline, Gregory P. Way, Alice Soragni
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- 4928 4928 免疫信号报告细胞系可在肿瘤微环境模型中实现对癌细胞、固有免疫细胞与适应性免疫细胞间串扰的定量监测 Immune signaling reporter cell lines enable quantitative monitoring of crosstalk among cancer, innate, and adaptive immune cells in tumor microenvironment model Hyeyoun Chang, John G. Foulke, Luping Chen, Meghan Sikes, Catherine McManus, Fang Tian
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- 4930 4930 细胞亲合力（Cell Avidity）：通过量化细胞-细胞及细胞-蛋白相互作用强度来理解治疗作用机制的新一代细胞结合分析 Cell Avidity: The Next-Gen cell binding assay to understand therapeutic mechanism of action through quantifying cell-cell and cell-protein interaction strength Keith Bailey, Riley Pihl, Michael SAVAGE, Trey Simpson
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- 4934 4934 使用离体微流控模型鉴定剪切应力下卵巢肿瘤细胞附着于腹膜间皮细胞的分子调控因子 Identifying molecular regulators of ovarian tumor cell attachment to peritoneal mesothelial cells under shear stress using an ex-vivo microfluidic model Jillian A. Martin, Breanna Baker, Vasilios Morikis, Alessandra DiMauro, Gregory D. Longmore, Whitney R. Grither
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- 4938 4938 代表巨噬细胞状态及免疫逃逸潜能机制决定因素的主调控蛋白的阐明与药理学靶向 Elucidation and pharmacologic targeting of master regulator proteins representing mechanistic determinants of macrophage state and immunoevasive potential Gaetano Viscido, Mikko Turunen, Zhouzerui Liu, Justyn Chang, Meghna S. Raman, Leo B. Dupire, Hanrui Zhang, Tim Olsen, Jeremy Worley, Aleksandar Obradovic, Andrea Califano
- 4939 4939 通过免疫原性张力图谱量化肿瘤免疫逃逸 Quantifying tumor immune escape through immunogenic tension mapping June-Young Koh, Ludmil B. Alexandrov
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