Late-Breaking Research: Population Sciences

• LB372 · PDF 理解突变图谱的起源 Understanding the origins of the mutational landscape Alexandra Keidel, Jazmine Virzi, Mina McKee, Mu-Rong Chao, Chiung-Wen Hu, Ludmil Alexandrov, Gunnar Boysen, Marcus Cooke
• LB373 · PDF 马里兰州癌症幸存者中个体层面和县级社会脆弱性与生活方式因素 Individual and county-level social vulnerability and lifestyle factors among cancer survivors in Maryland Camryn Mae Cohen, Kassandra I. Alcaraz, Katherine L. Ho, Avonne E. Connor
• LB374 · PDF 减去体重，风险犹存：肥胖成人尽管减重仍存在持续的癌症风险 Losing weight, not risk: Persistent cancer risk despite weight loss in adults with obesity Maren Weischer, Morten Dahl, Shoaib Afzal, Boerge G. Nordestgaard
• LB375 LB375 捷克共和国肺癌发病率与烟草控制及减害关系的生态学时间序列研究 Ecological time-series study of lung cancer incidence in relation to tobacco control and harm reduction in the Czech Republic Marian Hajduch, Jana Vrbkova
• LB376 · PDF 历史性红线划分与前列腺肿瘤中的DNA甲基化 Historical redlining and DNA methylation in prostate tumors Joseph Boyle, Camryn Cohen, Derrick Butts, Jimmie L. Slade, Yuji Zhang, Teklu B. Legesse, Ashley Johnson, Kimberly Clark, Jessica Wimbush, Nicholas Ambulos, Jing Yin, Jong Y. Park, Eberechukwu Onukwugha, Arif Hussain, Cheryl L. Knott, Kathryn H. Barry
• LB377 · PDF 卫星影像嵌入衍生的建成环境特征可预测癌症风险因素 Satellite embedding-derived built environment features predict cancer risk factors Chris Lim
• LB378 · PDF 癌症幸存者的复发恐惧与癌症筛查依从性：一项HINTS-SEER 2021研究 Fear of recurrence and cancer screening adherence among cancer survivors: A HINTS-SEER 2021 study Heidy N. Medina, Frank J. Penedo, Ashley N. Hatch, Matthew P. Schlumbrecht, Patricia I. Moreno
• LB379 · PDF 绝经前女性的内源性孕酮代谢与随后的乳腺癌风险 Endogenous progesterone metabolism in premenopausal women and subsequent breast cancer risk Susana Lozano-Esparza, May Shaabahn, Katie M. O’Brien, Dale P. Sandler, Alpa V. Patel, Lauren R. Teras, Xia Xu, Britton Trabert
• LB380 · PDF 2001-2019年美国HIV感染女性子宫切除校正后的宫颈癌发病率 Hysterectomy-corrected incidence of cervical cancer among women with HIV in the United States, 2001-2019 Adino T. Tsegaye, Aimée R. Kreimer, Jaimie Z. Shing, Megan A. Clarke, Tabassum Insaf, Jennifer H. Hayes, Qianlai Luo, Jennifer McGee-Avila, Ena Omoike, Ana Patricia Ortiz, Karen Pawlish, Nicolas Wentzensen, Eric A. Engels, Meredith S. Shiels
• LB382 · PDF 脊索瘤的发病模式和时间趋势：一项对美国超过6000例病例的基于人群的分析 Incidence patterns and temporal trends of chordoma: A population-based analysis of over 6000 cases in the United States Hyuna Sung, Chenxi Jiang, Hela Koka, Jiwei Bai, Alisa Goldstein, Xiaohong Yang
• LB383 LB383 美国HIV感染者中按分子亚型划分的乳腺癌风险 Breast cancer risk according to molecular subtype among people living with HIV in the United States Kaitlin White, Qianlai Luo, Ruth Pfieffer, Eric Engels, Meredith Shiels, Karen Pawlish, Analise Monterosso, Jennifer Hayes, Jonine Figueroa, Cameron Haas
• LB384 · PDF H3K27ac-HiChIP变异到基因映射证实了癌症驱动基因和致癌信号通路在黑色素瘤风险中的重要性 H3K27ac-HiChIP variant-to-gene mapping confirms the importance of cancer drivers and oncogenic signaling pathways in melanoma risk Rohit Thakur, G J M Shanika R Jayasinghe, Mai Xu, Linh Bui-Raborn, Jianxin Shi, Diptavo Dutta, Phuc H. Hoang, Mathias Seviiri, Christopher I. Amos, Andrew Bakshi, Anne E. Cust, Florence Demenais, David L. Duffy, Lars G. Fritsche, Jiali Han, Nicholas K. Hayward, Kiarash Khosrotehrani, Rajiv Kumar, John F. Thompson, Stuart MacGregor, Miguel Renteria, Diane T. Smelser, Sarah V. Ward, Maria Concetta Fargnoli, Paola Ghiorzo, Alisa M. Goldstein, Chiara Menin, David Millan-Esteban, Eduardo Nagore, Cristina Pellegrini, Susana Puig, Alex Stratigos, David C. Whiteman, Melanoma Meta-Analysis Consortium, Mark M. Iles, Lee E. Whelees, Rebecca I. Hartman, Maria Teresa Landi, Matthew H. Law, Kevin M. Brown
• LB385 · PDF 编码药物代谢酶和药物转运体基因中遗传变异的多基因风险评分与发热性中性粒细胞减少的关联 Polygenic risk score of genetic variants in genes encoding drug-metabolizing enzymes and drug transporters, in association with febrile neutropenia Sang Minh Nguyen, Jirong Long, Michael J. Robinson, Vicki Keedy, Travis Osterman, Tuya Pal, Ben Ho Park, Debra L. Friedman, Xiao Ou Shu
• LB386 · PDF 多人群GWAS荟萃分析鉴定出86个肾细胞癌易感区域 Multi-population GWAS meta-analysis identifies 86 susceptibility regions for renal cell carcinoma Diptavo Dutta, Careen Foord, Mitchell J. Machiela, Mark P. Purdue, Stephen J. Chanock, The Renal Cancer Genetics Consortium
• LB387 · PDF 全基因组关联研究鉴定出急性髓系白血病的种系易感位点 Genome-wide association study identifies germline susceptibility loci for acute myeloid leukemia Xueyao Wu, Filip Pirsl, Gabrielle Schmidt, Maryam Rafati, Aurélie Vogt, Herbert Higson, Jia Liu, Jiahui Wang, Shilpa Gaddam, Shengchao Li, Wael Saber, Yung-Tsi Bolon, Steven Moore, Sharon A. Savage, Stephen Chanock, Stephen Spellman, Peter Kraft, Shahinaz M. Gadalla
• LB388 · PDF 在多中心队列研究中，减重手术术式不同导致术后早期肝脏结局存在差异 Early postoperative liver outcomes differ by bariatric surgery procedure in multi-site cohort study Sindhu Karnam, Jaideep Behari, Kathryn Demanelis, Renwei Wang, Jian-Min Yuan
• LB390 · PDF 前列腺癌的遗传风险：来自前列腺癌测序联盟的见解 Genetic risk of prostate cancer: Insights from the Prostate Cancer Sequencing Consortium Yifan Zhang, Shuyan Cheng, Nicholas Boddicker, Matthew Lebo, Alexander S. F. Berry, Roni Haas, Ryan Hausler, Tokhir Dadaev, Heena Desai, Alex A. Rodriguez, Ravi K. Madduri, Andrew Hill, Xin Sheng, Susan M. Gundell, Mine Cicek, Penn Medicine Biobank, Regeneron Genetic Center, Hans Lilja, Olle Melander, Chris R. Gignoux, Isla P. Garraway, Bogdan Pasaniuc, Paul C. Boutros, Matt Oetjens, Adam S. Kibel, Robert J. Klein, Zsofia Kote-Jarai, Fergus J. Couch, Kara N. Maxwell, Burcu F. Darst, David V. Conti, Christopher A. Haiman, Fei Chen
• LB391 · PDF 三阴性乳腺癌的诊断前暴露、突变特征和免疫谱：PREMISE-TN项目概述 Pre-diagnostic exposures, mutational signatures, and immune profiles in triple-negative breast cancer: An overview of the PREMISE-TN project Deborah A. Tadesse, Clara Bodelon, Cheng Peng, Kristen D. Brantley, Margaux Delporte, Yujing J. Heng, Lauren Teras, Rulla M. Tamimi, Peter Kraft
• LB392 · PDF 高中生对防晒的感知成本与回报与其防晒安全行为之间的关联 Associations between perceived costs and rewards of sun protection and sun safety practices among high school students Omar U. Anwar, Yelena P. Wu, Tammy Stump, Marcelo M. Sleiman, Muriel R. Statman, Jennifer L. Hay, David B. Buller, Jakob D. Jensen, Douglas Grossman, Jincheng Shen, Benjamin Haaland, Kenneth P. Tercyak
• LB393 · PDF 乳腺癌患者治疗延迟与预后之间的关联：一项基于人群的队列研究 Association between treatment delay and prognosis among breast cancer patients: A population-based cohort study Hee-Jin Kim, Ji Yoon Baek, Soobin Lee, Aesun Shin
• LB394 LB394 按Lung-RADS分类的CT筛查及随访依从性：一项多中心队列研究 Adherence to CT screening and follow-up by Lung-RADS category: A multicenter cohort study Pratibha Shrestha, Michael K. Gould, Xiangyang Lou, Gerard A. Silvestri, Dejana Braithwaite, Shama D. Karanth
• LB395 · PDF 早期检测的潜在生存获益：多癌种模拟模型的开发与结果 Potential survival benefits from early detection: Development and results of a multi-cancer simulation model Nitish Aswani, Jiheum Park, Francesca Lim, Matthew Prest, Jennifer Ferris, Liyuan Gong, Jeong Yun Yang, Stella Kang, Chin Hur
• LB397 · PDF Samsung Organoids：一个基于GxP的药物筛选平台，利用患者来源肿瘤类器官并附带临床记录和多组学数据 Samsung Organoids: A GxP-based drug screening leveraging patient-derived tumor organoids platform accompanied with clinical records and multi-omics data Minhyung Lee, Sekyu Oh, Seongju Jeong, Sung Min Ha, Chihah Moon, Nayoun Choi, Yoonhyeok Kwon, Seahee Kim, Sangmyung Lee, Brian Hosung Min

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