PO.CL05.09 · 临床研究
Inflammation, Immunity, and Cancer
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6569 · PDF Single-cell transcriptomics reveal functional interaction between CD4+ T cells and B cells driving the activated peripheral immune phenotype in healthy women living with germline pathogenic BRCA1 variants Vince Kornel Grolmusz, Klaudia Horti-Oravecz, István Kelemen, István Likó, Anikó Bozsik, Tímea Pócza, Janos Papp, Szonja Polett Pósa, Lorinc S. Pongor, Henriett Butz, Attila Patócs
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6570 · PDF Assessment of multiplexed human and mouse cytokines in humanized mouse samples Andrew McDermott, Amanda Hrabovsky, Olivia Williams, Eric Bruder, Daniel Shoufler, Tina Raeber, Brooke Gilliam, Sineej Madathil, Kathryn MacPherson
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6571 · PDF Proliferative T cell infiltration is associated with colorectal cancer molecular subtypes and cancer specific survival Yasutoshi Takashima, Claire Elizabeth Thomas, Andressa Dias Costa, Sushma Thomas, Evertine Wesselink, Conghui Qu, Steven Gallinger, Robert C. Grant, Li Hsu, Marios Giannakis, Jeroen Huyghe, Daniel D. Buchanan, Shuji Ogino, Riki (Ulrike) Peters, Amanda I. Phipps, Jonathan A. Nowak
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6572 · PDF Obesity shapes a reversible immune microenvironment that fosters breast cancer growth Tao Zhang, Shimeng Liu, Yi Zhang, Alva Yijia Jiang, Zachary Sandusky, Na Zhang, Tara Akhshi, Nicole Traphagen, Jack Yueyang Wang, Lucas Tian, Esme Wheeler, Yingtian Xie, Rong Li, Buraq Ahmed, Genevra Kuziel, Capucine Heraud, Mohammed Mutaher, Henry Long, Kornelia Polyak, Myles A. Brown
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6573 · PDF Assessment of the T cell receptor repertoire in racially diverse prostate cancer patients Paula O. Cooper, Laila N. Scroggins, Sally Elsamanoudi, Amina Ali, Picabo Binette, Beatriz German Falcon, Leigh Ellis, Gregory T. Chesnut, Shyh-Han Tan, Cara C. Schafer
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6574 · PDF NK cell therapy enhances the efficacy of CDK4/6i in breast cancer Yinchong Wang, Evdokiya Reshetnikova, Nar Bahadur Katuwal, Anna Vilgelm
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6575 · PDF Investigating the role of glucocorticoid-induced leucine zipper (GILZ) in triple-negative breast cancer Devyn Aniya Hill, Jennifer B. Jacob
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6576 · PDF Integrative spatial transcriptomics reveals EMT-driven immune regulatory programs underlying metastasis in HNSCC Chih-Hung Chung, Han-Hsun Yu, Muh-Hwa Yang
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6578 · PDF Heat shock protein inhibitors suppress cytokine-induced DUOX2 mRNA and protein expression in human pancreatic cancer cells in a JAK, STAT dependent manner Yongzhong Wu, David J. Mallick, Allan Di, Smitha Antony, Jennifer Meitzler, Mariam M. Konaté, Becky Diebold, Krishnendu Roy, James H. Doroshow
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6579 · PDF Investigating the role of signal peptide peptidase in tumor immune evasion via Qa-1-mediated peptide presentation Roya Solhi, Clara Wolfe, Hu Chen, Achintya Perumal, Kyle Ockerman, Grant Brennan, Jiayao Ye, Adrienne H. Long, Marc Schwartz, Susan Klaeger, Steven A. Carr, Thorbald van Hall, Jon A. Weidanz, Soroush Ghaffari, Kathleen B. Yates, Robert T. Manguso, Qin Ma, Hakimeh Ebrahimi-Nik
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6580 · PDF A novel regulator of T-cell motility: Fhl2 controls CD8 + T-cell migration and infiltration Achintya Perumal, Grant Brennan, Jiayao Ye, Hu Chen, Roya Solhi, Omar I. Avila, Kathleen B. Yates, Robert T. Manguso, Stanley C. Huang, Haoxin Zhao, Giovanni Nigita, Zihai Li, No-Joon Song, Hazem E. Ghoneim, Ava Lowin, Kelley Ptak, Qin Ma, Hakimeh Ebrahimi-Nik
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6581 · PDF Reprogramming microglial and GAMs phenotype and function, with HDAC inhibitors to overcome immune suppression in glioblastoma Sonia Sebaoui
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6582 · PDF Cell surface plectin as a master regulator of tumor-immune interactions in pancreatic cancer Cody L. Wolf, Roxanne K. Ruiz, Sokchea Khou, Robert Cornelison, Edward Stelow, Karl M. Kowalewski, Matthew J. Lazzara, Amanda Poissonnier, Timothy N. J. Bullock, Lisa M. Coussens, Kimberly A. Kelly
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6583 · PDF Genetic characterization of KLRC2 deletion in racially diverse prostate cancer patients Laila Scroggins, Paula O. Cooper, Stefan DiFazio, Kun-Lin Ho, Sally Elsamanoudi, Jiji Jiang, Shyh-Han Tan, Ayesha A. Shafi, Cara C. Schafer
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6584 · PDF Spatial mapping and significance of IL12 signaling in non-small cell lung cancer Juan Guiza, Lucy Zheng, Barani Kumar Rajendran, Luciene Borges, Sandra Martinez-Morilla, Jillian M. Prendergast, Reniqua House, Kurt A. Schalper
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6585 · PDF DUOX2 is finely tuned by synergism between cytokines IL-6, IL-22, IL-17A, and TNFalpha in colon cancer Becky A. Diebold, Agnes Juhasz, Mariam M. Konaté, Jiamo Lu, Guojian Jiang, Jennifer L. Meitzler, Yongzhong Wu, Smitha Antony, David J. Mallick, Krishnendu K. Roy, James H. Doroshow
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6586 · PDF CCL3+ tumor cells orchestrate immune equilibrium and stemness maintenance in ESCC via IDE+ M2 macrophages and CCR3+ CAFs Beilei Liu, Licheng Tan, Jiayi Huang, Bowen Yao, Shuang Zhang, Mengsu Yang, Xin-Yuan Guan
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6587 · PDF Characterizing the autoreactome in thymoma-associated myasthenia gravis Rohan Maniar, Taylor Bauman, Patricia Sikorski, Karli Gilbert, Patrick J. Loehrer, Henry Kaminski, Linda Kusner
- 6588 6588 Exploring biomarker profiles in canine oncology using multiplex immunoassays Joseph B. Hwang, Tina Raeber, Brooke Gilliam, Anthony Saporita
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6589 · PDF Nrf2 as a therapeutic target to improve T cell function in muscle invasive bladder cancer (MIBC) Aprajita Tripathi, Nadine Santana-Magal, Jared Rack, Debolina Dasgupta, Benjamin L. Woolbright, Kalyani Pyaram
- 6590 6590 Investigation of carcinogenic effects of polystyrene microplastic on human bladder cancer cells Sahab Ram
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6591 · PDF Cross platform same slide multi-omics reveals Treg heterogeneity and links to spatial niche variability in pre-cancerous colonic inflammation Daniel Jimenez-Sanchez, Matthew H. Ingalls, Sanghamithra korukonda, Brian J. Lane, Isabella Marie Peshek, Patrick Danaher, Prajan Divakar, Oliver Braubach, Parambir S. Dulai
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6592 · PDF In vitro neutrophil assays to support immuno-oncology drug development Christoph Schifflers, Martijn Vlaming, Sofie Pattyn
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6593 · PDF B-cell guided inflammatory cascade perpetuates ICI-mediated colitis Roza Nurieva, Naimah Turner, Synat Keam, Jocelynn Colunga
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6594 · PDF Establishing ex vivo models for targeting leukemic stem cells to investigate relapse and refractory pediatric leukemias Sashi Kandel, Jacqelyn M. Nemechek, Tykeem Manor, John N. Maina, John M. Perry
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6595 · PDF Memory B cell Responses Ignite Anti-Tumor Immunity by Activating CD8+ T cell Cytotoxicity Kendrick Nguyen, Monika Quackenbush, Georgia Lattanzi, Daniel Hollern, Sara Basbous, Haley Rodriguez, Daniela Boassa, Jingting Yu, Asona Lui, April Wehner, Aatish Thennavan, Peter H. Watson
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6596 · PDF Understanding DAP12-independent antitumor activation in KIR-based CAR T cells Qian Zhang, Kevin Zhou, Zhongze Sun, Chen Zhang, Marta Chebotar, Michael C. Milone