Inflammation, Immunity, and Cancer

• 6569 · PDF 单细胞转录组学揭示CD4+ T细胞与B细胞之间的功能性相互作用，驱动携带种系致病性BRCA1变异健康女性的活化外周免疫表型 Single-cell transcriptomics reveal functional interaction between CD4+ T cells and B cells driving the activated peripheral immune phenotype in healthy women living with germline pathogenic BRCA1 variants Vince Kornel Grolmusz, Klaudia Horti-Oravecz, István Kelemen, István Likó, Anikó Bozsik, Tímea Pócza, Janos Papp, Szonja Polett Pósa, Lorinc S. Pongor, Henriett Butz, Attila Patócs
• 6570 · PDF 人源化小鼠样本中多重人和小鼠细胞因子的评估 Assessment of multiplexed human and mouse cytokines in humanized mouse samples Andrew McDermott, Amanda Hrabovsky, Olivia Williams, Eric Bruder, Daniel Shoufler, Tina Raeber, Brooke Gilliam, Sineej Madathil, Kathryn MacPherson
• 6571 · PDF 增殖性T细胞浸润与结直肠癌分子亚型和癌症特异性生存相关 Proliferative T cell infiltration is associated with colorectal cancer molecular subtypes and cancer specific survival Yasutoshi Takashima, Claire Elizabeth Thomas, Andressa Dias Costa, Sushma Thomas, Evertine Wesselink, Conghui Qu, Steven Gallinger, Robert C. Grant, Li Hsu, Marios Giannakis, Jeroen Huyghe, Daniel D. Buchanan, Shuji Ogino, Riki (Ulrike) Peters, Amanda I. Phipps, Jonathan A. Nowak
• 6572 · PDF 肥胖塑造了一种可逆的免疫微环境，促进乳腺癌生长 Obesity shapes a reversible immune microenvironment that fosters breast cancer growth Tao Zhang, Shimeng Liu, Yi Zhang, Alva Yijia Jiang, Zachary Sandusky, Na Zhang, Tara Akhshi, Nicole Traphagen, Jack Yueyang Wang, Lucas Tian, Esme Wheeler, Yingtian Xie, Rong Li, Buraq Ahmed, Genevra Kuziel, Capucine Heraud, Mohammed Mutaher, Henry Long, Kornelia Polyak, Myles A. Brown
• 6573 · PDF 种族多样性前列腺癌患者T细胞受体库的评估 Assessment of the T cell receptor repertoire in racially diverse prostate cancer patients Paula O. Cooper, Laila N. Scroggins, Sally Elsamanoudi, Amina Ali, Picabo Binette, Beatriz German Falcon, Leigh Ellis, Gregory T. Chesnut, Shyh-Han Tan, Cara C. Schafer
• 6574 · PDF NK细胞疗法增强CDK4/6i在乳腺癌中的疗效 NK cell therapy enhances the efficacy of CDK4/6i in breast cancer Yinchong Wang, Evdokiya Reshetnikova, Nar Bahadur Katuwal, Anna Vilgelm
• 6575 · PDF 探究糖皮质激素诱导亮氨酸拉链蛋白(GILZ)在三阴性乳腺癌中的作用 Investigating the role of glucocorticoid-induced leucine zipper (GILZ) in triple-negative breast cancer Devyn Aniya Hill, Jennifer B. Jacob
• 6576 · PDF 整合空间转录组学揭示驱动HNSCC转移的EMT驱动型免疫调控程序 Integrative spatial transcriptomics reveals EMT-driven immune regulatory programs underlying metastasis in HNSCC Chih-Hung Chung, Han-Hsun Yu, Muh-Hwa Yang
• 6578 · PDF 热休克蛋白抑制剂以JAK、STAT依赖的方式抑制人胰腺癌细胞中细胞因子诱导的DUOX2 mRNA和蛋白表达 Heat shock protein inhibitors suppress cytokine-induced DUOX2 mRNA and protein expression in human pancreatic cancer cells in a JAK, STAT dependent manner Yongzhong Wu, David J. Mallick, Allan Di, Smitha Antony, Jennifer Meitzler, Mariam M. Konaté, Becky Diebold, Krishnendu Roy, James H. Doroshow
• 6579 · PDF 探究信号肽肽酶通过Qa-1介导的肽段呈递在肿瘤免疫逃逸中的作用 Investigating the role of signal peptide peptidase in tumor immune evasion via Qa-1-mediated peptide presentation Roya Solhi, Clara Wolfe, Hu Chen, Achintya Perumal, Kyle Ockerman, Grant Brennan, Jiayao Ye, Adrienne H. Long, Marc Schwartz, Susan Klaeger, Steven A. Carr, Thorbald van Hall, Jon A. Weidanz, Soroush Ghaffari, Kathleen B. Yates, Robert T. Manguso, Qin Ma, Hakimeh Ebrahimi-Nik
• 6580 · PDF T细胞运动性的新型调控因子：Fhl2控制CD8+ T细胞的迁移和浸润 A novel regulator of T-cell motility: Fhl2 controls CD8 + T-cell migration and infiltration Achintya Perumal, Grant Brennan, Jiayao Ye, Hu Chen, Roya Solhi, Omar I. Avila, Kathleen B. Yates, Robert T. Manguso, Stanley C. Huang, Haoxin Zhao, Giovanni Nigita, Zihai Li, No-Joon Song, Hazem E. Ghoneim, Ava Lowin, Kelley Ptak, Qin Ma, Hakimeh Ebrahimi-Nik
• 6581 · PDF 用HDAC抑制剂重编程小胶质细胞和GAMs的表型与功能，以克服胶质母细胞瘤中的免疫抑制 Reprogramming microglial and GAMs phenotype and function, with HDAC inhibitors to overcome immune suppression in glioblastoma Sonia Sebaoui
• 6582 · PDF 细胞表面plectin作为胰腺癌肿瘤-免疫相互作用的主控调节因子 Cell surface plectin as a master regulator of tumor-immune interactions in pancreatic cancer Cody L. Wolf, Roxanne K. Ruiz, Sokchea Khou, Robert Cornelison, Edward Stelow, Karl M. Kowalewski, Matthew J. Lazzara, Amanda Poissonnier, Timothy N. J. Bullock, Lisa M. Coussens, Kimberly A. Kelly
• 6583 · PDF KLRC2缺失在种族多样的前列腺癌患者中的遗传学表征 Genetic characterization of KLRC2 deletion in racially diverse prostate cancer patients Laila Scroggins, Paula O. Cooper, Stefan DiFazio, Kun-Lin Ho, Sally Elsamanoudi, Jiji Jiang, Shyh-Han Tan, Ayesha A. Shafi, Cara C. Schafer
• 6584 · PDF IL12信号在非小细胞肺癌中的空间定位及其意义 Spatial mapping and significance of IL12 signaling in non-small cell lung cancer Juan Guiza, Lucy Zheng, Barani Kumar Rajendran, Luciene Borges, Sandra Martinez-Morilla, Jillian M. Prendergast, Reniqua House, Kurt A. Schalper
• 6585 · PDF DUOX2在结肠癌中受细胞因子IL-6、IL-22、IL-17A和TNFalpha之间协同作用的精细调控 DUOX2 is finely tuned by synergism between cytokines IL-6, IL-22, IL-17A, and TNFalpha in colon cancer Becky A. Diebold, Agnes Juhasz, Mariam M. Konaté, Jiamo Lu, Guojian Jiang, Jennifer L. Meitzler, Yongzhong Wu, Smitha Antony, David J. Mallick, Krishnendu K. Roy, James H. Doroshow
• 6586 · PDF CCL3+肿瘤细胞通过IDE+ M2巨噬细胞和CCR3+ CAF在ESCC中协调免疫平衡与干性维持 CCL3+ tumor cells orchestrate immune equilibrium and stemness maintenance in ESCC via IDE+ M2 macrophages and CCR3+ CAFs Beilei Liu, Licheng Tan, Jiayi Huang, Bowen Yao, Shuang Zhang, Mengsu Yang, Xin-Yuan Guan
• 6587 · PDF 胸腺瘤相关重症肌无力中自身反应组的表征 Characterizing the autoreactome in thymoma-associated myasthenia gravis Rohan Maniar, Taylor Bauman, Patricia Sikorski, Karli Gilbert, Patrick J. Loehrer, Henry Kaminski, Linda Kusner
• 6588 6588 利用多重免疫分析法探索犬肿瘤学中的生物标志物图谱 Exploring biomarker profiles in canine oncology using multiplex immunoassays Joseph B. Hwang, Tina Raeber, Brooke Gilliam, Anthony Saporita
• 6589 · PDF Nrf2作为改善肌层浸润性膀胱癌（MIBC）中T细胞功能的治疗靶点 Nrf2 as a therapeutic target to improve T cell function in muscle invasive bladder cancer (MIBC) Aprajita Tripathi, Nadine Santana-Magal, Jared Rack, Debolina Dasgupta, Benjamin L. Woolbright, Kalyani Pyaram
• 6590 6590 聚苯乙烯微塑料对人膀胱癌细胞致癌效应的研究 Investigation of carcinogenic effects of polystyrene microplastic on human bladder cancer cells Sahab Ram
• 6591 · PDF 跨平台同一切片多组学揭示癌前结肠炎症中Treg异质性及其与空间生态位变异的关联 Cross platform same slide multi-omics reveals Treg heterogeneity and links to spatial niche variability in pre-cancerous colonic inflammation Daniel Jimenez-Sanchez, Matthew H. Ingalls, Sanghamithra korukonda, Brian J. Lane, Isabella Marie Peshek, Patrick Danaher, Prajan Divakar, Oliver Braubach, Parambir S. Dulai
• 6592 · PDF 用于支持免疫肿瘤学药物研发的体外中性粒细胞检测 In vitro neutrophil assays to support immuno-oncology drug development Christoph Schifflers, Martijn Vlaming, Sofie Pattyn
• 6593 · PDF B细胞主导的炎症级联反应使ICI介导的结肠炎持续存在 B-cell guided inflammatory cascade perpetuates ICI-mediated colitis Roza Nurieva, Naimah Turner, Synat Keam, Jocelynn Colunga
• 6594 · PDF 建立靶向白血病干细胞的离体模型以研究复发和难治性儿童白血病 Establishing ex vivo models for targeting leukemic stem cells to investigate relapse and refractory pediatric leukemias Sashi Kandel, Jacqelyn M. Nemechek, Tykeem Manor, John N. Maina, John M. Perry
• 6595 · PDF 记忆B细胞应答通过激活CD8+ T细胞的细胞毒性引燃抗肿瘤免疫 Memory B cell Responses Ignite Anti-Tumor Immunity by Activating CD8+ T cell Cytotoxicity Kendrick Nguyen, Monika Quackenbush, Georgia Lattanzi, Daniel Hollern, Sara Basbous, Haley Rodriguez, Daniela Boassa, Jingting Yu, Asona Lui, April Wehner, Aatish Thennavan, Peter H. Watson
• 6596 · PDF 理解基于KIR的CAR T细胞中不依赖DAP12的抗肿瘤活化 Understanding DAP12-independent antitumor activation in KIR-based CAR T cells Qian Zhang, Kevin Zhou, Zhongze Sun, Chen Zhang, Marta Chebotar, Michael C. Milone

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