PO.CL09.04 · 临床研究
Real World Impact of Prognostic and Predictive Parameters
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7849 · PDF 循环肿瘤DNA微小残留病灶作为乳腺癌临床试验终点的真实世界全景分析 Real-world landscape analysis of circulating tumor DNA minimal residual disease as a clinical trial endpoint in breast cancer Momo Arai, Alaa Khalilaa, Ahmed Elkhanany
- 7850 7850 实体瘤功能性药物敏感性检测的真实世界一致性分析及胰腺癌前瞻性观察性病例系列 Real-world concordance analysis of functional drug sensitivity testing in solid cancers with prospective observational case series of pancreatic cancer Weng Tong Ho, Masturah Rashid, Jhin Jieh Lim, John Seng Hooi Low, Yugarajah Asokumaran, Shin Yee Wong, David Khie Siong Hii, Edward Kai-Hua Chow
- 7851 7851 乳腺癌早期临床试验转诊与结局:Gustave Roussy的一项前瞻性筛查队列和真实世界I期项目经验。 Early-phase clinical trial referral and outcomes in breast cancer: A prospective screening cohort and a real-world Phase I program experience at Gustave Roussy. Alessandra Spata, Matthieu Roulleaux-Dugage, Berenger Poirier, Christophe Massard, Sophie C. Postel-Vinay, Antoine Hollebecque, Madona Sakkal, Kaïssa Ouali, Rastislav Bahleda, Yohann Loriot, Joana M. Ribeiro, Barbara Pistilli, Cyril Roussel-Simonin
- 7852 7852 LGBTQ+癌症患者中的烟草、尼古丁、大麻和酒精使用:一家NCI指定综合癌症中心的真实世界分析 Tobacco, nicotine, cannabis, and alcohol use among LGBTQ+ patients with cancer: Real-world analysis at an NCI-Designated Comprehensive Cancer Center Min-Jeong Yang, Shahrzad A. Zamani, Matthew B. Schabath
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7853 · PDF 七基因突变特征预测膀胱癌免疫治疗获益 A seven-gene mutation signature predicts immunotherapy benefit in bladder cancer I-Cheng Huang, Chun-Nan Kuo
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7854 · PDF 功能获得型TP53突变对HER2阴性晚期胃癌预后的影响 Prognostic impact of gain-of-function TP53 mutations on outcomes in HER2-negative advanced gastric cancer Jong-Ho Kim, Jwa Hoon Kim, Ji Won Lee
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7855 · PDF 黑色素瘤患者标本中Ki67表达的转录组分析揭示不同的免疫特征 Transcriptomic profiling of Ki67 expression in melanoma patient specimens reveals distinct immune signatures Eleanor A. Fallon, Kei Kawashima, Kazuaki Takabe
- 7856 7856 Avera测序与分析方案(ASAP)研究患者中克隆性造血的患病率及其与心血管健康的关联 Prevalence and association of clonal hematopoiesis with cardiovascular health in patients of the Avera sequencing and analytics protocol (ASAP) Study Mikayla Bendix, McKenna Perrin, Ryan Vaca, Padmapriya Swaminathan, Crystal Hattum, Shakeel Mir, Lucia Speroni, Emily Teslow, David Starks, Benjamin Solomon, William Spanos, Rachel Elsey, Tobias Meissner
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7857 · PDF 多模态真实世界数据揭示结直肠癌对TOP1i临床应答的预测因素并优化ADC策略 Multi-modal real-world data uncovers predictors of clinical response to TOP1i and optimizes ADC strategies in colorectal cancer Alireza Tafazzol, Sebastián Cruz-González, Xu Shi, Zoltan Dezso, Douglas E. Kline, Jack Chen, Peter J. Ansell, Relja Popovic, Rong Chen, Josue Samayoa, Xi Zhao, Weilong Zhao
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7858 · PDF 机器学习预测真实世界小细胞肺癌患者中的视网膜母细胞瘤蛋白(Rb)功能 Machine learning predicts retinoblastoma (Rb) function in real-world small cell lung cancer patients Sana Parveen, Neshatul Haque, Emma T. Corcoran, Sebastià Franch-Expósito, Prerna Jain, Jacob Mercer, Anthony J. Trimboli, Gustavo W. Leone, Navonil de Sarkar, Abdul R. Naqash, Christine M. Lovly, Paul Fields, Hui-Zi Chen
- 7859 7859 在基于电子健康记录(EHR)的队列中探索代谢功能障碍相关脂肪性肝病(MASLD)的多层次危险因素 Exploring multilevel risk factors for metabolic dysfunction-associated steatotic liver disease (MASLD) in an electronic health record (EHR)-based cohort Janet N. Chu, Mindy Hebert-Derouen, Alison Canchola, Alyssa Cortella, Pushkar Inamdar, Hashem B. El-Serag, Scarlett L. Gomez, Salma Shariff-Marco
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7860 · PDF 融合基因机器学习模型改善肝细胞癌的临床结局预测 Fusion gene machine learning models improve clinical outcome prediction of hepatocellular carcinoma Jian-Hua Luo, Silvia Liu, Yanping Yu
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7861 · PDF 利用真实世界临床数据转化多种癌症类型中的时序多疾病路径 Translating temporal multi-disease pathways in multiple cancer types using real-world clinical data Md Ashad Alam
- 7862 7862 HIV感染者黑色素瘤的人群分析与免疫学图谱 Population analysis and immunologic landscape of melanoma in people living with HIV Lindsay Barger, Derek Wang, Ashley Saravia, Valeria Mezzano-Robinson, Gyles Ward, Cynthia Loomis, Carly Feldman, Madalina Tuluc, Rino S. Seedor, Peter J. Gaskill, Anna E. Coghill, Gita Suneja, Iman Dehzangi, Jenna Hope, George Jour, Gabriele Romano
- 7863 7863 阿司匹林和塞来昔布的使用与ER+/HER2-转移性乳腺癌的总生存:一项大型真实世界队列分析 Aspirin and celecoxib use and overall survival in ER+/HER2- metastatic breast cancer: A large real-world cohort analysis Mostafa Eysha, Mohanad Elchouemi, Harshitha Popuri, Gaurav Periapattanam, Arsalaan Asad, Yasmin Youssef, Ahmed Elkhanany, Sumit Gaur
- 7864 7864 基于CDK4/6抑制剂的方案与化疗在既往治疗过的HR+/HER2+转移性乳腺癌中的真实世界总生存与医疗资源利用:一项TriNetX全球协作网络分析 Real-world overall survival and healthcare utilization with CDK4/6 inhibitor based regimens versus chemotherapy in previously treated HR+/HER2+ metastatic breast cancer: A TriNetX Global Collaborative Network analysis Mostafa Eysha, Usman Hussain, Mohanad Elchouemi, Mariah Black, Sharon Siby, Wanyu Zhang, Arsalaan Asad, Ahmed Elkhanany
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7865 · PDF 在技术增强型多学科肿瘤会议上讨论的患者的生存特征 Survival profile of patients presented at technology-enhanced multidisciplinary cancer conferences Opuruiche Ibekwe, Carmelo Gaudioso, Quratulain Sabih, Han Yu, Peter Frederick, Ellis G. Levine, Chukwumere E. Nwogu
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7866 · PDF BMI特异性和亚型特异性的分子聚类揭示尼日利亚与美国队列乳腺癌中不同的肥胖机制 BMI- and subtype-specific molecular clusters reveal distinct obesity mechanisms in breast cancer across Nigerian and U.S. cohorts Oyomoare Osazuwa-Peters, Jovita Kokwesiga Byemerwa, Omolola Salako, Adetola Daramola, Olusegun Isaac Alatise, Gabriel Ogun, Tomi Akinyemiju
- 7867 7867 黑色素瘤中遗传风险、社会经济地位和生活方式因素的独立效应:一项大规模基因-环境分析 Independent effects of genetic risk, socioeconomic status, and lifestyle factors in melanoma: A large-scale gene-environment analysis Elle Kim, Nilanjan Chatterjee
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7868 · PDF 免疫检查点抑制剂治疗中皮肤与全身的相互作用:全局免疫激活的证据 Skin and systemic interplay in immune checkpoint inhibitor therapy: Evidence of global immune activation Elle Kim, Joel Chaim Sunshine