PO.MCB08.05 · 分子与细胞生物学
Genomic Approaches to Define Tumor Biology and Clinical Stratification
- 7261 7261 全面的多组学分析揭示胰腺实性假乳头状肿瘤的分子异质性和发育特征 Comprehensive multi-omics profiling reveals molecular heterogeneity and developmental signatures in solid pseudopapillary neoplasm of the pancreas Dong-Ju Shin, Jin Ho Choi, Sang Hyub Lee, In Rae Cho, Kyung-Min Lee, Ji Kon Ryu, Woo Hyun Paik, Jin-Ku Lee
- 7262 7262 一套采用新型文库制备靶向富集方案、可全自动无人值守运行的系统，用于检测液体活检和肿瘤样本中的超低频突变 A fully automated walkaway system programmed with a novel library prep target enrichment protocol for detection of ultra-low frequency mutations in liquid biopsy and tumor samples Saharnaz Bigdeli, Jan Godoski, Bernd Buehler, Bahram Arezi, Brandyn Clark, Denise Rhodes, schryl castaneda, Bonita Lam, Yun Bao, ji zhu, Gilbert Amparo, Neelima Mehendale, Khine Win, Karen Chapman
- 7263 7263 通过泛癌CGP与定制化肉瘤融合检测相结合，识别软组织肉瘤患者的分子改变 Identification of molecular alterations in soft tissue sarcoma patients with combined pan-cancer CGP and bespoke sarcoma fusion detection testing Chaugiang Duong, Ryan Bender, Nathan Montgomery, Fernando J. Lopez-Diaz
-
-
- 7266 7266 通过全面的多组学分析深化对非肌层浸润性膀胱癌（NMIBC）疾病生物学的认识 Advancing insights into disease biology of non-muscle invasive bladder cancer (NMIBC) through comprehensive multi-omics analysis Siew Kee Low, Yoshiyuki Nagumo, Xuesong Lyu, Jiarui Zhang, Jie Zhao, Kozaburo Tanuma, Satoka Kinase, Karen Urtishak, Neil Beeharry, Shibu THOMAS, Longen Zhou, Hiroyuki Nishiyama
-
-
- 7269 7269 一种经优化的、基于磁珠的双核酸提取方法的开发与验证，用于对稀缺FFPE肿瘤标本进行高产量基因组分析 Development and validation of an optimized, bead-based dual nucleic acid extraction method for high-yield genomic profiling of scarce FFPE tumor specimens Nripesh Prasad, Rebecca Beatty, Rachel Marshall, Chan-Ho Lee, Elizabeth Coffey, Annamaria Szanto
-
- 7271 7271 临床基因组学和功能基因组学支持ARID1A缺失在促结缔组织增生性小圆细胞肿瘤进展中的作用 Clinical genomic and functional genomic support for a role of ARID1A loss in progression of desmoplastic small round cell tumor Tom Zhang, Andrea Gazzo, Christopher A. Febres-Aldana, Juan Luis Gomez Martis, Lee Spraggon, Romel Somwar, Marc Ladanyi
-
-
- 7275 7275 拉丁裔胃腺癌的分子特征分析确定同源重组缺陷和TGF-beta通路为侵袭性基因组稳定型肿瘤的治疗靶点 Molecular characterization of Latino gastric adenocarcinomas identifies homologous recombination deficiency and TGF-beta pathways as targets for aggressive genomically stable tumors Dennis J. Montoya, Ana Patricia Estrada-Florez, Paul Lott, Katherine Chiu, Javi Villalpando, Shriveda Reddy, Jasmine Diaz Sezati, Fabian Castro, Guadalupe M Polanco-Echeverry, Magdalena Echeverry de Polanco, Javier Torres, Mabel Bohorquez, Luis G. Carvajal-Carmona
-
- 7278 7278 单细胞RNA测序分析揭示接受ibrutinib治疗的CLL患者中不同的肿瘤和免疫抑制性T细胞表型 Single-cell RNA-seq analysis reveals distinct tumor and immunosuppressive T-cell phenotypes in CLL patients treated with ibrutinib. Shanmugapriya Thangavadivel, Jami Shaffer, Shrilekha Misra, Samon Benrashid, Britten Gordon, Alexander He, Wantong Li, Konur Oyman, Annika Chura, Shelby Cabrera, Altan Turkoglu, Tzung-Huei Lai, Kerry Rogers, Seema Bhat, John C. Byrd, James S. Blachly, Jennifer A. Woyach, Bradley Blaser
-
-
- 7281 7281 免疫衰老和抗原呈递缺陷定义了膀胱癌中预先存在的BCG无反应状态 Immune senescence and antigen presentation defects define a pre-existing state of BCG unresponsiveness in bladder cancer KyounJun Lee, Jee Soo Park, Myung Eun Lee, Jongchan Kim, Hyoung-oh Jeong, Minseo Kim, Won Sik Ham, Semin Lee
- 7282 7282 未经治疗乳腺癌的综合多组学图谱揭示驱动免疫热型和冷型表型的共存肿瘤-免疫生态系统 A comprehensive multiomics atlas of treatment-naïve breast cancer uncovers co-occurring tumor-immune ecosystems driving immune hot and cold phenotypes Hani Jieun Kim, Beata Kiedik, Kate Harvey, Sehrish Kanwal, James Douglas, John Reeves, Alexander Lobanov, Daniel L. Roden, Sophie Van Der Leij, Mun N. Hui, Aziz Al’Khafaji, Elgene Lim, Sean M. Grimmond, Joakim Lundeberg, Charles M. Perou, Alexander Swarbrick
- 7283 7283 一名接受TNF-alpha抑制剂治疗患者的IDH野生型胶质母细胞瘤基因组图景:对风险分层和治疗决策的意义 Genomic landscape of IDH-wild-type glioblastoma in a patient treated with TNF-alpha inhibitor: Implications for risk stratification and therapeutic decision-making Suryanarayan Mohapatra, Natarajan Ganesan
-
