LBPO.BCS01 · 生物信息与计算 · Late-Breaking
Late-Breaking Research: Bioinformatics, Computational Biology, Systems Biology, and Convergent Science 1
- LB159 LB159 在肿瘤学空间转录组数据上对单模态与多模态基础模型进行基准评测的实用指南 A practical guideline for benchmarking unimodal and multimodal foundation models on spatial transcriptomics data in oncology Anna C. Wahl (née Schaar), Dasha Valter, Lisa Sikkema, Stefan G. Stark, Zelda E. Mariet, Tokuwa Kanno, Ediem Al-Jibury, Tobias Heinen, Liam Gonzalez, Marin G. M. Scalbert
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- LB161 LB161 新抗原发现流程的比较研究揭示突变新肽序列生成中的差异 A comparative study of neoantigen discovery pipelines uncovers discrepancies in the generation of mutated neopeptide sequences Ibel Carri, Angela Frentzen Worley, Ashmitaa Logandha Ramamoorthy Premlal, Gauri Renjith, Malachi Griffith, Jason Greenbaum, Alessandro Sette, Bjoern Peters, Zeynep Kosaloglu-Yalcin
- LB162 LB162 Twistcgp流程：一个用于转化肿瘤学中全面基因组分析的可移植开源工作流程 Twistcgp pipeline: A portable, open-source workflow for comprehensive genomic profiling in translational oncology Nils Homer, Erin McAuley, Zach Norgaard, James Flynn, Rebecca Barnard, Tina Han
- LB163 LB163 头颈癌的空间分析揭示两种具有不同上皮-间质转化模式的生态系统 Spatial analysis of head and neck cancer reveals two ecosystems with distinct modes of epithelial-to-mesenchymal transition Dor Simkin, Thomas F. Barrett, Lingling Zhang, Michael J. Moore, Alissa R. Greenwald, Noam G. Darnell, Michael Mints, Salma Ramadan, Victoria Yu, Riley DZ Mullins, Jesse Zaretsky, Porter Bischoff, Douglas Adkins, Wade L. Thorstad, Sana D. Karam, Randall C. Paniello, Jason T. Rich, Ryan S. Jackson, Patrik Pipkorn, Paul A. Zolkind, Guangyong Peng, R. Alex Harbison, Rebecca Chernock, Anuraag S. Parikh, Sidharth V. Puram, Itay Tirosh
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- LB166 LB166 HER2阳性乳腺癌脑转移中与tucatinib暴露相关的基因组和转录组变化 Genomic and transcriptomic changes associated with tucatinib exposure in HER2-positive breast cancer brain metastases Savannah C. Roy, Anna Guarnieri, Pradeep Bhartiya, Thomas Danhorn, Andrew Goodspeed, Hannah Parris, Virginia F. Borges, James Costello, David R. Ormond, Elena Shagisultanova
- LB168 LB168 通过迭代式多等位基因反卷积与集成深度学习，利用JANUS推进肽-MHC结合预测 Advancing peptide-MHC binding prediction with JANUS through iterative multi-allele deconvolution and ensemble deep learning Alan Perez-Rathke, Justin Balko, Jens Meiler
- LB169 LB169 scCAP：一个面向本体的大语言模型框架，用于分层且标准化的单细胞类型注释 scCAP: An ontology-aware large language model framework for hierarchical and standardized single-cell type annotation Dongkwan Shin, Seok-Won Jang, Jonghyun Lee, Juyeon Cho
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- LB171 LB171 基于AI的B2SC识别驱动HER2+乳腺癌对T-DXd耐药的预先存在的TOP2A/E2F活跃细胞群 AI-based B2SC identifies pre-existing TOP2A/E2F-active populations driving resistance to T-DXd in HER2+ breast cancer Se-eun Han, Minwoo Jung, Taewoo Kim, Jaeeun Park, Minji Seo, Jangsoon Lee, Sang Youn Rhie
- LB172 LB172 基于RNA-seq的结直肠癌分子与微环境分层：一个韩国真实世界队列研究 RNA-seq-based molecular and microenvironmental stratification of colorectal cancer in a Korean real-world cohort Jinseon Yoo, Kyu Jin Song, Jimin Kim, Keeok Haam, Soobok Joe, Jongbum Jeon
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