PO.BCS01.01 · 生物信息与计算

Application of Bioinformatics to Cancer Biology 1

30 张海报 27 张含资料时间 Apr 19 2026 2:00PM 区域 Section 3

39 · PDF ESCC的单细胞解析鉴定出可靶向的起源细胞和早期肿瘤发生中的治疗脆弱性 Single-cell dissection of ESCC identifies targetable cells-of-origin and therapeutic vulnerabilities in early tumorigenesis Kyung Pil Ko, Jie Zhang, Sohee Jun, Jae-Il Park
40 · PDF 整合转录组学和免疫克隆演化定义肺腺癌的逐步分子进展 Integrated transcriptomic and immune-clonal evolution defines stepwise molecular progression in lung adenocarcinoma Kang Qin, An Qin, John V. Heymach
41 · PDF 基因组和转录组数据的整合分析揭示胰腺癌前病变进展 Integrative analysis of genomic and transcriptomic data informs precancer progression in the pancreas Kathleen Noller, Jiaying Lai, Daniel Lesperance, Ricky S. Adkins, Ahmed M. Elhossiny, Paola A. Guerrera, Kimal Rajapakshe, Anirban Maitra, Anup Mahurkar, Owen White, Marina Pasca Di Magliano, Michael Ochs, Luciane Tsukamoto Kagohara, Laura Wood, Rachel Karchin, Elana Judith Fertig
42 · PDF 改造纳米抗体的抗原依赖性稳定性：一种用于调节纳米抗体细胞内稳定性的生物信息学工具 Engineering antigen-dependent stability in nanobodies: A bioinformatics tool for tuning intracellular nanobody stability Alvin Fu, Rohith Leeladharan, Junhee Park, Shriya Kapila, Liuhan Ke, Amina Mohamed, Cynthia Zhao, Radha Manohar Kapgate, Anh Leith, Jonathan Tang
43 · PDF 三阴性乳腺癌中EZH2与多巴胺D1受体信号之间的表观遗传-神经递质串扰 Epigenetic-neurotransmitter crosstalk between EZH2 and dopamine D1 receptor signaling in triple-negative breast cancer Maciej Pietrzak, Xilal Y. Rima, Gautam Sarathy, Shivani Dhekne, Lara Rizotto, Dario Palmieri, Sanjay Gupta, Daniel G. Stover, Giovanni Nigita, Eduardo Reátegui, Pierre Giglio, Christian Rolfo, Eswar Shankar
44 · PDF scSubtype2.0：单细胞分辨率下的乳腺癌分子亚型预测器 scSubtype2.0: Predictor of breast cancer molecular subtypes at single cell resolution Alexander V. Lobanov, Hani Jieun Kim, Sehrish Kanwal, Kate Harvey, John Reeves, Marcel Batten, Beata Kiedik, Daniel L. Roden, Mun N. Hui, Kym Pham Stewart, Oliver Hofmann, Sandra O’Toole, Elgene Lim, Sean M. Grimmond, Alexander Swarbrick, Charles M. Perou
45 · PDF 鉴定种系AEN多态性作为宫颈癌的风险因素 Identification of germline AEN polymorphisms as risk factors in cervical cancer Golya Shahrokhi, Mari Kyllesø Halle, Vinodh Srinivasasainagendra, Jianqing Zhang, Aishwarya Sundaresan, Roshan Kumar, Shafiq Shaikh, Nichol He, Camilla Krakstad, Sadeep Shrestha, Paul Auer, Janet Rader, Hemant Tiwari, Akinyemi I. Ojesina
46 · PDF 人类癌症中单碱基替换的高清特征 High-definition signatures of single-base substitutions in human cancer Jessica N. Au, Marcos Diaz-Gay, Raviteja Vangara, Pilar Gallego-Garcia, Mousumy Kundu, S.M Ashiqul Islam, Maria Zhivagui, Zichen Jiang, Christopher Steele, Sarah Moody, Michael R. Stratton, Paul J. Brennan, Ludmil B. Alexandrov
47 · PDF 使用PEPMatch和CEDAR鉴定癌症新表位的非经典来源 Identifying noncanonical sources of cancer neoepitopes using PEPMatch and CEDAR Daniel Marrama, Ibel Carri, Nina Blazeska, Randi Vita, Hannah K. Carter, Morten Nielsen, Alessandro Sette, Zeynep Kosaloglu-Yalcin, Bjoern Peters
48 · PDF 体细胞NFKBIZ变异在单细胞分辨率下调节炎症 Somatic NFKBIZ v ariant modulates inflammation at single-cell resolution Catherine H. Feng, Andrew R. D'Avino, Anders W. Rasmussen, Dan Landau
49 · PDF PER3-RORB轴定义了一种与头颈部鳞状细胞癌生存改善相关的肿瘤抑制性昼夜节律状态 The PER3-RORB axis defines a tumor-suppressive circadian state associated with improved survival in head and neck squamous cell carcinoma Harold Nathan Tan, Oriol Mirallas, Paul Selvadurai, Michael Wotman, Luana Sousa, Neal Akhave, Khaled Sanber, Renata Ferrarotto, George R. Blumenschein, Maura L. Gillison, Faye M. Johnson, Timothy A. Yap
50 · PDF 空间转录组学揭示小细胞肺癌中转录重编程与免疫逃逸的模式 Spatial transcriptomics uncovers patterns of transcriptional reprogramming and immune evasion in small cell lung cancer Emmanuel S. Spanos, Meng Wang, Amin Sabet, Esther Redin, Charles M. Rudin, Joseph Chan
51 · PDF RAS(ON)多重选择性抑制重塑胰腺癌中的癌相关成纤维细胞亚型和细胞外基质 RAS(ON) multi-selective inhibition remodels cancer-associated fibroblast subtypes and extracellular matrix in pancreatic cancer Lorenzo Tomassoni, Allison C. Hess, Kevin Munoz Forti, Hun Jin Jeong, Deanna J. Besart, Tanner C. Dalton, Urszula N. Wasko, Carmine F. Palermo, Stephen A. Sastra, Chang H. Lee, Andrea Califano, Simon Schworer, Marie C. Hasselluhn, Kenneth P. Olive
52 · PDF 量化拷贝数扩增的选择优势以揭示卵巢癌治疗靶点 Quantifying the selective advantage of copy number amplifications to reveal therapeutic targets in ovarian cancer Meng Liu, Jeff Mandell, Jeffrey Peter Townsend
53 · PDF RNA融合:一种尚未开发的新抗原来源,用于基于免疫的全亚型乳腺癌预防和治疗 RNA fusions: An untapped source of neoantigens for immune based breast cancer prevention and treatment across all subtypes of breast cancers Anjana Bhardwaj, Chathurani Ranathunge, Shiyanth Thevasagayampillai, Aaranyah Kandasamy, Brandon H. Than, Constance T. Albarracin, Isabelle Bedrosian
54 54 整合连接图谱资源,为个体三阴性乳腺癌患者优选并个性化候选药物 Integrating connectivity mapping resources to prioritize and personalize drug candidates for individual triple negative breast cancer patients Lily D. Taub, Anna Byrd, Daniel J. Clarke, Ido Diamant, Criseyda Martinez, Elisa Port, Hanna Y. Irie, Avi Maayan
55 · PDF 分化状态与免疫相互作用促成AML中的药物反应 Differentiation state and immune interaction contribute to drug response in AML Natasha R. A. Black, Dharani Thirumalaisamy, Mira Rajagopalan, Trevor Enright, Melissa Stewart, Evan Lind, Elie A. Traer, Jeffrey W. Tyner, Olga H. Nikolova
56 · PDF COSMIC:推进体细胞突变的癌症基因组学知识库 COSMIC: Advancing the cancer genomics knowledgebase of somatic mutations Madhumita Madhumita, Madiha Ahmed, Joanna Argasinska, David Armstrong, Nidhi Bindal Dhir, Denise Carvalho-Silva, Lucie Chadelle, Patrick Dao, Stephen Duke, Giovanna Fasanella, Muhammad Fouzan, Abishekraj Gnanasambandam, Avirup Guha Neogi, Susan Haller, Bhavana Harsha, Balazs Hetenyi, Leonie Hodges, Steven Jupe, Rachel Lyne, Thomas Maurel, Karen McLaren, Thomas Mutimer, Sumodh Nair, Hanna Najgebauer, Helder Pedro, Sophie Poole, Amaia Sangrador-Vegas, Zoe Sheard, Manpreet Singh Chawla, Michael Starkey, Rebecca Steele, Sari Ward, Ellen Wiedemann, Jennifer Wilding, Siew Yit Yong, Jon Teague
57 · PDF 功能通路分析揭示乳腺癌中临床HER2状态与下游效应器激活之间的不一致 Functional pathway analysis reveals discordance between clinical HER2 status and downstream effector activation in breast cancer Salim Arslan, Julian Schmidt, Cher Bass, Foivos Ntelemis, J Carl Barrett, Oscar Maiques, Jakob Nikolas Kather, Pahini Pandya
58 · PDF 通过空间转录组学表征化疗后卵巢癌的肿瘤-基质界面 Characterizing tumor-stroma interfaces in chemotherapy-treated ovarian cancer via spatial transcriptomics Po-Yuan Chen, Tyler M. Yasaka, Tzu-Hung Hsiao, Tai-Ming Ko, Yu-Chiao Chiu
59 · PDF 癌症基因组中的突变特征改变参与细胞信号网络的短线性蛋白基序 Mutational signatures in cancer genomes alter short linear protein motifs involved in cellular signaling networks Jigyansa Mishra, Masroor Bayati, Nina Adler, Zoe P. Klein, Kevin C. L. Cheng, Juri Reimand
60 · PDF CpGene：一个基于DNA甲基化的生物标志物发现平台 CpGene: a DNA methylation-based biomarker discovery platform Konstantinos Lazaros, Vasiliki Tzelepi, Christopher J. Logothetis, Aristidis G. Vrahatis, Susan (Souzana) Logotheti
61 · PDF 利用泛癌蛋白质组学图谱界定跨实体瘤的生存空间生物标志物 Defining spatial biomarkers of survival across solid tumors using a pan-cancer proteomics atlas Khoa Huynh, Joaquin Reyna, Bruno Matuck, KEVIN BYRD, Jinze Liu
62 · PDF 人类各类癌症中m6A RNA甲基化的全面表征 Comprehensive characterization of m 6 A RNA methylation across human cancers Yining Zhao, Ke Chen, Hu Chen, Yizhe Song, Kamalika Mojumdar, Wei Liu, Stephanie H Ting, Ayush Semwal, Hui Shen, Li Ding, Genomic Data Analysis Network, Katherine Hoadley, Han Liang
63 · PDF 瘤内白色念珠菌与非小细胞肺癌（NSCLC）的缺氧和不良结局相关 Intratumoral Candida albicans associates with hypoxia and poor outcomes in non small cell lung cancer (NSCLC) Dipankor Chatterjee, Dennis J. Grencewicz, Alexander Loncar, Ruohan Wu, Alex Samouilov, Sylvain Ferrandon, McKenzie Kreamer, Yogita Mehra, Aspen Carson, Rebecca Hoyd, Shiva Jahanbakhshi, Fouad Choueiry, Matthew Anderson, Martin Benej, Dustin Bosch, Jiangjiang (Chris) Zhu, Jinghai Wu, Thèrése Bocklage, Martin McCarter, Ahmad Tarhini, Bodour Salhia, Christopher A. Moskaluk, Gregory Riedlinger, Song Yao, Ashiq Masood, Sheetal Hardikar, Mmadili N. Ilozumba, Cornelia M. Ulrich, Abdul Rafeh Naqash, Carlos H.F. Chan, Craig D. Shriver, Dinesh Pal Mudaranthakam, Aaditya Pallerla, Michelle Churchman, Robert J. Rounbehler, Laura Chambers, Matthew F. Kalady, Nicholas C. Denko, David P. Carbone, Dan Spakowicz
64 · PDF CDK4/6抑制剂耐药机制：来自单细胞核测序和空间转录组学的见解 Mechanisms of resistance to CDK4/6 inhibitors: Insights from single-cell nucleus sequencing and spatial transcriptomics Seung-eun Bang, EunChae Kim, Won-Ji Ryu, Hyein Jung, Yoonjin Cha, Joohyuk Sohn, Gun Min Kim, Kyoo Hyun Kim, Byungjin Hwang, Min Hwan Kim
65 65 整合空间转录组学、数字病理学与Genomics England的全基因组数据以表征结直肠癌的肿瘤及其微环境 Integrating spatial transcriptomics and digital pathology with whole-genome data from Genomics England to characterise the tumour and it's microenvironment in colorectal cancer Luke McNickle, Assya Legrini, Yoana Doncheva, Mari-Claire McGuigan, Ghazal Latifi, Claire Kennedy Dietrich, Molly McKenzie, Phimmada Hatthakarnkul, Tom Wright, Leonor Patricia Schubert Santana, Emma McCargow, Cong Chen, Henry M. Wood, Jon Laye, Gemma Hemmings, Caroline Cartlidge, Derek Magee, Phil Quirke, Joanne Edwards, Nigel Jamieson
66 · PDF 基因共扩增与结构模式揭示癌症中染色体外DNA的原理 Gene co-amplification and structural patterns reveal principles of extrachromosomal DNA in cancer Jens Luebeck, Ted Liefeld, Edwin Huang, Forrest Kim, Bhargavi Dameracharla, Michael A. Chan, Dhruv Khatri, Kyra Fetter, Kaiyuan Zhu, Thorin Tabor, Soyeon Kim, Hoon Kim, Roel Verhaak, Michael M. Reich, Paul S. Mischel, Jill P. Mesirov, Vineet Bafna
67 · PDF 基于基因对的机器学习模型在乳腺癌治疗优先级排序中的验证 Validation of a gene pair-based machine learning model for treatment prioritization in breast cancer Rishi Nair, Nicholas R. Mistry, Roy Khalife, Anthony M. Magliocco
68 68 在高细胞外葡萄糖条件下，YAP-TEAD依赖性VASP表达增加TNBC细胞的硬度和迁移能力 YAP-TEAD-dependent VASP expression increases cell stiffness and migration in TNBC cells under high extracellular glucose conditions Wonkyung Lee, Seeun Oh, Tae-Hyung Kim

在会议检索中浏览本分会场