PO.CT01.02 · 临床试验
First-in-Human Phase I Clinical Trials
- CT041 CT041 针对长链非编码RNA TUG1的寡核苷酸疗法治疗复发性胶质母细胞瘤的研究者发起的I期试验 Investigator-initiated phase I trial of an oligonucleotide therapeutic targeting long noncoding RNA TUG1 for recurrent glioblastoma Ryuta Saito, Fumiharu Ohka, Yohei Mineharu, Makoto Ohno, Miho Suzuki, Keiko Shinjo, Shoichi Deguichi, Yoshiki Shiba, Aya Sato, Yoshiki Arakawa, Yoshitaka Narita, Shiro Akinaga, Yutaka Kondo
- CT042 CT042 E-SYNC T细胞（一种自体抗EGFRvIII SynNotch受体诱导的抗EphA2/IL13Ra2 CAR T细胞）治疗成人EGFRvIII+胶质母细胞瘤的首次人体试验 First-in-human trial of E-SYNC T-cells, an autologous anti-EGFRvIII SynNotch receptor-induced anti-EphA2/IL13Ra2 CAR T-cells, in adult patients with EGFRvIII+ glioblastoma Payal B. Watchmaker, Jennifer L. Clarke, Ricardo Almeida, Akane Yamamichi, Abigail Hansen, Harika T. Gopi, Karishma Kumar-Wessel, Megna Reddy, David Y. Oh, Jacob S. Young, Nicholas Butowski, Nancy A. Oberheim Bush, Jennie W. Taylor, John de Groot, Joanna Phillips, Annette M. Molinaro, Brain R. Shy, Wendell Lim, Hideho Okada
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