Molecular Targets 1

• 2979 · PDF MAPK driven kinetochore instability as a biomarker and therapeutic vulnerability in glioblastoma Jennifer DeLuca, Patrick J. Paddison
• 2980 · PDF SMARCA2 and SMARCA4 expression in cancer: A tissue microarray study on 14,966 tumors from 134 different tumor types Nina Schraps, Anne Menz, Florian Lutz, Viktoria Chirico, Florian Viehweger, David Dum, Ria Schlichter, Andrea Hinsch, Fiete Gehrisch, Christoph Fraune, Christian Bernreuther, Seyma Büyücek, Martina Kluth, Claudia Hube-Magg, Katharina Möller, Viktor Reiswich, Andreas M. Luebke, Patrick Lebok, Baris Mercanoglu, Nathaniel Melling, Thilo Hackert, Guido Sauter, Maximilian Lennartz, Till S. Cauditz, Andreas H Marx, Ronald Simon, Stefan Steurer, Eike Burandt, Natalia Gorbokon, Maria Christina Tsourlakis, Sarah Minner, Till Krech, Morton Freytag
• 2981 · PDF PM54 targets oncogenic transcriptional networks across multiple cancer types Ismael Fernández-Miranda, Javier Robles, Maria José Guillen, Pablo Avilés, Marcelo L. Ribeiro, Carmen Cuevas
• 2982 · PDF Role of high mobility group nucleosome-binding domain-containing protein 3 (HMGN3) in prostate cancer progression a novel target for therapeutic intervention Vikkram Venkatesan, Jeffrey Mathew, Janani Harikrishnan, Gnanasekar Munirathinam
• 2983 · PDF Genome-wide CRISPRi screen identifies RPS27 as a novel synthetic lethal target for TP53 mutant cancers Stephen Paik, Yi Yu, Ashley H. Choi, Samuel R. Meier, Shangtao Liu, Binzhang Shen, Shanchuan Zhao, Xuewen Pan, Jannik N. Andersen, Teng Teng
• 2984 · PDF In situ and functional analysis of Integrin-alpha 5 reveals its role in tumor progression in non-small cell lung cancer Mirei Ka, Takahiro Ando, Munetoshi Hinata, Kousuke Watanabe, Akiko Kunita, Masanori Kawakami, Masaaki Sato, Hiroyuki Okada, Hironori Hojo, Tetsuo Ushiku, Cecilia C. Krona, Patrick Micke, Katsutoshi Oda, Hidenori Kage
• 2985 · PDF TRIB2 as a therapeutic vulnerability in ALK-rearranged non-small cell lung cancer Jitender Monga, Sudha Sadasivan, Sang-Yoon Lee, Sharad K. Suthar, Craig Rogers, Shirish Gadgeel
• 2986 · PDF Vertical inhibition of the autophagy pathway promotes growth arrest and apoptotic cell death in pancreatic ductal adenocarcinoma Mallory K. Roach, Jonathan M. DeLiberty, Seamus Degan, Lily M. Pita, Elyse G. Schechter, Noah L. Pieper, Runying Yang, Mariaelena Pieronon, Clint A. Stalnecker, Emanuel Frank Petricoin, Kirsten L. Bryant
• 2987 · PDF Cordycepin inhibits Intrahepatic cholangiocarcinoma progression by targeting NAT10-mediated ac4C RNA modification of VCAN Yuting Zhao, Yinzhao Chen, Yuhan Fang, Kai Luo, Jialin Qu, Dong Shang, Caiming Xu, Guixin Zhang
• 2988 · PDF A druggable genome screen identifies b-catenin transcription targets as desmoid cell vulnerabilities Jia Hu, Tianjie Pu, Vladislav Tsiperson, Lakshana Senthilkumar, Katherine Prendergast, Narasimhan P. Agaram, Marco Russo, Sameul Singer, Ralph Garippa, Meera Hameed, Aimee Crago
• 2989 · PDF ONCO Prime platform enables discovery of synthetic lethal targets for genetically stratified cancers Andrzej Mazan, Eliza Zimolag, Joanna Szuszkiewicz, Marcin Serocki, Oleksii Bryzghalov, Izabella Wieckowska, Marcelina Chmiel, Katarzyna Sarad, Julia Wirkijowska, Wiktoria Luczak, Szymon Woroszylo, Dariusz Klonski, Kamil Kus, Andrew Thomason, Michal Mikula, Rafal Dziadziuszko, Krzysztof Brzozka
• 2990 · PDF PSMA expression in neoplastic cells and tumor-associated vasculature: A tissue microarray study evaluating 12,409 cancers from 135 different tumor types Fiete Gehrisch, Alexandra Malinowski, Anne Menz, Florian Lutz, Viktoria Chirico, Florian Viehweger, David Dum, Ria Schlichter, Andrea Hinsch, Christoph Fraune, Christian Bernreuther, Seyma Büyücek, Martina Kluth, Claudia Hube-Magg, Georgia Makrypidi-Fraune, Nina Schraps, Katharina Möller, Andreas M. Luebke, Patrick Lebok, Guido Sauter, Maximilian Lennartz, Frank Jacobsen, Till S. Clauditz, Andreas H. Marx, Ronald Simon, Stefan Steurer, Eike Burandt, Nathalia Gorbokon, Maria C. Tsourlakis, Sarah Minner, Till Krech, Morton Freytag, Viktor Reiswich
• 2991 Superior detection of NTRK fusions across Chinese solid tumors using amplicon-based DNA and RNA NGS co-detection compared with hybrid-capture DNA-NGS Mingqian Lu
• 2992 · PDF The role of FOXD1 in the anaplastic transformation of thyroid cancer Aki Inase, Mitsuyoshi Hirokawa, Miyoko Higuchi, Naoyoshi Onoda, Takuya Higashiyama, Taiji Koyama, Shiro Kimbara, Masanori Teshima, Hironobu Minami, Ken-Ichi Nibu, Mitch A. Phelps, Naomi Kiyota
• 2993 · PDF Deciphering the key role of the glycosyltransferase GALNT14 in osteosarcoma tumorigenesis D. Isabel Petrescu, Tajhal D. Patel, Shoshana Leeds, Jeffrey Ritzenthaler, Heath Bradley, Juan Dou, Jason T. Yustein
• 2994 · PDF Integrative pathway analysis of I-SPY2 HER2+ breast cancers reveals drug-repurposing opportunities Kingsley V. Chow, Tam Binh Bui, Denise M. Wolf, Annuska Glas, Zheyun Xu, Gillian L. Hirst, I-SPY2 investigators, Amy Clark, Julia Wulfkhule, Angie DeMichele, Emanuel Frank Petricoin, Laura J. Esserman, Jennifer Rosenbluth, Laura van 't Veer, Rosalyn W. Sayaman
• 2995 · PDF ATRX in-frame fusions promote endogenous chemoresistance programs but yield immunotherapeutic vulnerabilities in neuroblastoma Mohammad Ali Mohammad Nezhady, Sheetal Bhatara, Siarhei Hladyshau, Estevez Prado Daniel, Vernon Ebegboni, Alja Kozulic-Pirher, Arnav Barpujari, Bo Wang, Yuan Feng, Qiqi Jin, Xueying Liu, Paul Geeleher, Xiaotu Ma, Jiyang Yu, Emily Bernstein, Kelly Goldsmith, Hunter Jonus, Adam D. Durbin
• 2996 · PDF Internalization of B7-H3 is enhanced by cholesterol disruption in esophageal cancer cells Takashi Imajima, Kenji Tsuchihashi, Takafumi Kitazono, Wataru Kusano, Eishi Baba
• 2997 · PDF LTA4H promotes intrahepatic cholangiocarcinoma progression via mTOR activation and T-cell exhaustion Ganglian Lin, Jinhui Wang, Yizhuo He, Fangkai Feng, Chongming Zheng, Yi Wang
• 2998 · PDF Disrupted clock pathway during lineage plasticity and prostate cancer progression Nishat Manzar, Himisha Beltran
• 2999 · PDF Targeting cholesterol pathways in p53 deficient head and neck cancers Jovanka Gencel-Augusto, Nuo Tian, Akshat Singhal, Hua Li, Liam Woerner, Arthur Goldberg, Daniel E. Johnson, Jennifer Rubin Grandis
• 3000 · PDF Tumor Treating Fields (TTFields) may weaken glioblastoma network connectivity, with implications for malignancy Julius Beichert, Jonas A. Kretz, Jena Kim, Xiaoyu Ma, Daniel Dominguez Azorín, Andreas E. Moor, Haikun Liu, Miriam Ratliff
• 3001 · PDF Therapeutic inhibition of oncogenic miR-181a processing for cancer therapy Grace McIntyre, Jessica Mathew, Zoe Jackson, Meghana Choragudi, Madison Uyemura, Aaron Robida, Renju Jacob, Jose Colina, Jiaming Yao, Hang Yang Wong, Rachel Offenheim, Mark Kunkel, Sriram Chandrasekaran, Peter Toogood, Analisa DiFeo
• 3002 · PDF Aneuploidy as a metabolic liability: Exploiting novel therapeutic targets in squamous cell carcinomas Nadja Zhakula, Sejal Jain, Zeinab Amini-Farsani, Jiankang Zhang, Mari Nakamura, Laura Byron, Joan J. Castellano-Perez, Tannishtha Reya, Matthew L. Meyerson, Alison M. Taylor
• 3003 · PDF Impact of sequencing technology on actionable fusion detection in precision oncology for lung cancer Gabriel Bandeira do Carmo, Rafael Canfield Brianese, Karina Miranda Santiago, Adriano Bonaldi, Marina De Brot Andrade, Giovana Tardin Torrezan, Dirce Maria Carraro
• 3004 · PDF OXTR targeted local therapy could be a promising strategy for pleural mesothelioma Ichidai Tanaka, Hideyuki Itoigawa, Kazumi Hori, Shoichiro Fukuda, Heng Huang, Haruka Takata, Taketo Kato, Mitsuo Sato, Yoshitaka Sekido, Shinobu Shimizu, Tatsuhiro Ishida, Toyofumi Fengshi Yoshikawa, Makoto Ishii
• 3005 · PDF Ex vivo trial of ODM-212, a novel pan-TEAD inhibitor, in patients with primary and metastatic solid tumors Juha K. Rantala, Eetu Välimäki, Janne Suhonen, Reetta Riikonen, Anu-Maarit Moilanen
• 3006 · PDF Genomic determinants of PIK3CA mutation driven breast cancer initiation Snehal B. Bhandare, Ruizhong Wang, Poornima Bhat-Nakshatri, Stephanie Adama, Sarah R. Spivak, Farzaneh Behzadnia, Cihat Erdogan, Hongyu Gao, Yunlong Liu, Lylah H. Hutson, Xin Dauterman, George Sandusky, Harikrishna Nakshatri

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