PO.TB03.04 · 肿瘤生物学
Characterization of Metastases by Imaging and Profiling
- 2103 2103 全基因组DNA甲基化图谱揭示转移性甲状腺癌关键致癌通路的表观遗传学改变及预后生物标志物 Genome-wide DNA methylation profiling uncovers epigenetic alterations in key oncogenic pathways and prognostic biomarkers of metastatic thyroid cancer Sara Alnassar, Jana Almusallam, Nada Almutairi, Najla Albader, Amal Qattan, Yufei Shi
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- 2108 2108 利用患者来源异种移植模型对转移性小细胞肺癌的蛋白质组学见解 Proteomic insights into metastatic small cell lung cancer using patient derived xenograft models Sára Surguta, Laura Svajda, Zsolt Megyesfalvi, Bence Ferencz, Ildikó Kovács, Vivien Téglás, Lilla Horváth, Szilvia Török, Balázs Döme, Melinda Rezeli, Jozsef Tovari
- 2109 2109 非小细胞肺癌脑转移灶与配对原发肿瘤中胶原结构的分析支持来源于脑外的成纤维细胞募集 Analysis of collagen architecture in brain metastasis and paired primary tumors in Non-small cell lung cancer supports the recruitment of fibroblasts originating outside the brain Jordi Alcaraz, Alejandro Bernardo Suarez, Gabriela Caballero, Patricia Fernandez-Nogueira, Marc Rico-Pastó, Victoria Batto, Iban Aldecoa Ansorregui
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- 2111 2111 绘制免疫-血管特征图谱以表征三阴性乳腺癌脑转移中的血脑屏障破坏与肿瘤定植 Mapping immuno-vascular signatures to characterize blood brain barrier disruption and tumor colonization in triple negative breast cancer brain metastasis. Shruti Rodrigues, Maria Jose Godoy Calderon, Manali Patwardhan, VK Gadi
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- 2113 2113 光学成像与数字病理学评估提升患者来源转移性乳腺癌模型的转化价值与稳健性 Optical imaging and digital pathology evaluation increases the translational value and robustness of patient-derived metastatic breast cancer models Philipp Meyer, Laura Neagu-Lund, Eva Oswald, Aleksandra Zuraw, Loreen Weichert, Michael Staup, Julia B. Schueler
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- 2119 2119 原发肿瘤的空间基因表达谱与来自侵袭前沿的侵袭性CTC释放相关，导致OSCC的早期复发 Spatial gene expression profile of primary tumor is associated with the release of aggressive CTCs from the invasive front, leading to early recurrence in OSCC Geeta S. Boora, Anshika Chauhan, Suvradeep Mitra, Arindam Maitra, Sushmita Ghoshal, Arnab Pal
- 2120 2120 空间分辨转录组分析揭示口腔鳞状细胞癌最差侵袭模式的分子特征 Spatially resolved transcriptomic analysis revealed the molecular characteristics of the worst pattern of invasion in oral squamous cell carcinomas Seungeun Lee, Yeonbi Han, Dohoon Kim, Sumin Lee, Amos Chungwon Lee, Wonjae Cha, Jin-Ku Lee
- 2122 2122 整合转录组分析鉴定卵巢癌转移中疟疾相关信号通路和可重定位的候选药物 Integrative transcriptomic analysis identifies malaria-associated signaling pathways and repurposable drug candidates for ovarian cancer metastasis Dr. Muhibullah Ghafoorzai, Arsalan Riaz, Dr. Faisal F. Khan
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- 2125 2125 患者来源的原位异种移植模型重现胰腺癌的腹膜播散并勾勒其转录组、调控和空间程序 Patient-derived orthotopic xenograft models recapitulate the peritoneal dissemination of pancreatic cancer and delineate its transcriptomic, regulatory, and spatial programs Takaaki Furukawa, Kohei Kumegawa, manabu takamatsu, Kenichi Miyata, Sumito Saeki, Chikako Shibata, Takafumi Mie, Takeshi Okamoto, Tsuyoshi Takeda, Takashi Sasaki, Masato Ozaka, Miwa Tanaka, Shunji Takahashi, Tetsuo Noda, Yao Ryoji, Naoki Sasahira, Reo Maruyama
