PO.TB03.04 · 肿瘤生物学
Characterization of Metastases by Imaging and Profiling
- 2103 2103 Genome-wide DNA methylation profiling uncovers epigenetic alterations in key oncogenic pathways and prognostic biomarkers of metastatic thyroid cancer Sara Alnassar, Jana Almusallam, Nada Almutairi, Najla Albader, Amal Qattan, Yufei Shi
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2104 · PDF RNA editing based risk model to predict extrahepatic metastasis in colorectal cancer liver metastasis Eiki Miyake, Kunitoshi Shigeyasu, Toshiaki Takahashi, Kazuya Moriwake, Masashi Kayano, Yuhei Kondo, Yuya Sakurai, Shunsuke Nakamura, Masafumi Takahashi, Kaori Nitta, Kazuya Yasui, Tomokazu Fuji, Kosei Takagi, Hiroshi Tazawa, Toshiyoshi Fujiwara
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2105 · PDF Transcriptomic insights into MAO B inhibition and bevacizumab synergy in colorectal cancer model Unnati Hemant Shah, Shivani Soni, Pooja Mittal, Lesly Torres-Gonzalez, Michela Bartolini, Steve Soto Trujillo, Yitzhar Goretsky, Francesca Battaglin, Goar Smbatyan, Yan Yang, Joshua Millstein, Karam Ashouri, Sandra Algaze, Wu Zhang, Jean Chen Shih, Heinz-Josef Lenz
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2106 · PDF High-throughput and accurate intrasplenic injection in mice for metastatic cancer modeling using a robotic injection device Alexis Stanley, James Tseng, Ryan Gessner, Tomasz J. Czernuszewicz, Jeffrey D. Peterson
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2107 · PDF Genomic landscape of melanoma brain metastases: Real-world analysis and comparison with public melanoma cohorts Dina Elantably, Joseph B. Parker, Jakob Hamilton, Ahmed Abdelhakeem, Oluwatayo Adeoye, Saivaishnavi Kamatham, Winston Tan, Arkadiusz Z. Dudek, Anastasios Dimou, Matthew S. Block, Robert McWilliams, Svetomir Markovic, Mahesh Seetharam, Roxana Dronca, Ruqin Chen
- 2108 2108 Proteomic insights into metastatic small cell lung cancer using patient derived xenograft models Sára Surguta, Laura Svajda, Zsolt Megyesfalvi, Bence Ferencz, Ildikó Kovács, Vivien Téglás, Lilla Horváth, Szilvia Török, Balázs Döme, Melinda Rezeli, Jozsef Tovari
- 2109 2109 Analysis of collagen architecture in brain metastasis and paired primary tumors in Non-small cell lung cancer supports the recruitment of fibroblasts originating outside the brain Jordi Alcaraz, Alejandro Bernardo Suarez, Gabriela Caballero, Patricia Fernandez-Nogueira, Marc Rico-Pastó, Victoria Batto, Iban Aldecoa Ansorregui
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2110 · PDF Characterizing drivers of invasiveness in basal-like triple negative breast cancer Perrin Black, Destiny Ball, Antonisha McIntosh, Alayjha Edwards, Sewedo Ajisegiri, Nobelle I. Sakwe, Ngoc Vuong, Olga Korolkova, Qingguo Wang, Amos M. Sakwe
- 2111 2111 Mapping immuno-vascular signatures to characterize blood brain barrier disruption and tumor colonization in triple negative breast cancer brain metastasis. Shruti Rodrigues, Maria Jose Godoy Calderon, Manali Patwardhan, VK Gadi
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2112 · PDF Image activated cell sorting reveals distinct morpholomic manifolds in breast cancer cell lines Andres Jose Nevarez, Lan Zheng, Songyun Li, Nicholas E. Navin
- 2113 2113 Optical imaging and digital pathology evaluation increases the translational value and robustness of patient-derived metastatic breast cancer models Philipp Meyer, Laura Neagu-Lund, Eva Oswald, Aleksandra Zuraw, Loreen Weichert, Michael Staup, Julia B. Schueler
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2114 · PDF Murinemodels of bone and brain metastasis for preclinical cancer research Hongyan Sun, Fang Zhu, Yan Wang, Yuan Fang, Yuqing Han, Jianming Xu, Huixin Yang, Xiang Gao
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2115 · PDF Development of the cf-MMSP assay for enhanced detection of methylated cfDNA in breast cancer by liquid biopsy Liqun Zhang, Wenfei Xia, Mary Jo Fackler, Gang Yu, Madison Pleas, Leslie Cope, Saraswati V. Sukumar
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2116 · PDF Genomic landscape of 1007 pan-cancer brain metastases Ramzi Homsi, Henry Walch, Roshal Patel, Anna Skakodub, Emily Miao, James Lee, Chengcheng Gui, Mitchell Parker, Zachariya Yazdani, Michel A. Padilla Mazzeo, Claire Cooper, Kyle Sporn, Brandon Imber, Yao Yu, Jessica Wilcox, Nelson Moss, Ahmet Turan Ilica, Rabih Bou-Nassif, Joseph Stember, Christopher Jackson, Connor Kinslow, Gustav Cederquist, Caleb Lareau, Helena A. Yu, Soo Ryum Yang, Pedram Razavi, Joseph Chan, Kenny Kwok Hei Yu, Walid Khaled Chatila, Nikolaus Schultz, Luke R. G. Pike
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2117 · PDF Single cell chromatin accessibility profiling of human metastatic tumor cells Valentina Opazo-Mellado, Maria Jose Oviedo, Diego Figueroa, Carlos Perez, Laura Hernandez, Joanna Phillips, Jeroen Roose, Hugo Gonzalez
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2118 · PDF Cell surface anchored ratiometric probes for heparan sulfate enable live cell bioimaging and suppression of cancer cell migraion Minwoo Jeong, Hyun Jung Hwang, Donghee Kang, Min-Ji kim, Lee Keun-Hyung, Jae-Seon Lee
- 2119 2119 Spatial gene expression profile of primary tumor is associated with the release of aggressive CTCs from the invasive front, leading to early recurrence in OSCC Geeta S. Boora, Anshika Chauhan, Suvradeep Mitra, Arindam Maitra, Sushmita Ghoshal, Arnab Pal
- 2120 2120 Spatially resolved transcriptomic analysis revealed the molecular characteristics of the worst pattern of invasion in oral squamous cell carcinomas Seungeun Lee, Yeonbi Han, Dohoon Kim, Sumin Lee, Amos Chungwon Lee, Wonjae Cha, Jin-Ku Lee
- 2122 2122 Integrative transcriptomic analysis identifies malaria-associated signaling pathways and repurposable drug candidates for ovarian cancer metastasis Dr. Muhibullah Ghafoorzai, Arsalan Riaz, Dr. Faisal F. Khan
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2123 · PDF A high resolution spatial transcriptomic atlas of the bone marrow microenvironment pre and post prostate cancer seeding Haley du Bois, Alberto Chaves, Mostafa Nasr, Tao Li, Karl Nyman, Ryan Bishop, Conor C. Lynch
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2124 · PDF Patient-derived CSF and ascites organoids reveal divergent metastatic mechanisms in advanced gastric cancer Byeong Gyu Yoon, Chan Hee Park, Woo Sun Kwon, Tae Soo Kim, Sun Young Rha
- 2125 2125 Patient-derived orthotopic xenograft models recapitulate the peritoneal dissemination of pancreatic cancer and delineate its transcriptomic, regulatory, and spatial programs Takaaki Furukawa, Kohei Kumegawa, manabu takamatsu, Kenichi Miyata, Sumito Saeki, Chikako Shibata, Takafumi Mie, Takeshi Okamoto, Tsuyoshi Takeda, Takashi Sasaki, Masato Ozaka, Miwa Tanaka, Shunji Takahashi, Tetsuo Noda, Yao Ryoji, Naoki Sasahira, Reo Maruyama