PO.CL12.01 · 临床研究
Molecular Classification and Tumor Biology in Cancer
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- 3871 3871 每周卡铂/紫杉醇联合cemiplimab（wCP+C）治疗晚期/转移性黏膜型头颈部鳞状细胞癌（a/mHNSCC）II期试验中疗效与生存的分子相关因素 Molecular correlates of response and survival in a phase II trial of weekly carboplatin/paclitaxel plus cemiplimab (wCP+C) in advanced/metastatic mucosal head and neck squamous cell carcinoma (a/mHNSCC) Mateus Trinconi Cunha, Fahad Rind, Priyanka Bhateja, Esmerina Tili, David Konieczkowski, Darrion Mitchell, Sujith Baliga, Sung Jun Ma, Simeng Zhu, Gogineni Emile, John Grecula, Nolan Seim, Catherine Harring, Lauren Miller, Abberly Lott Limbach, Kang Stephen, James W. Rocco, Christian Rolfo, Dukagjin Blakaj, Marcelo Bonomi
- 3873 3873 非肌层浸润性膀胱癌的分子异质性揭示了具有相反卡介苗（Bacillus Calmette-Guérin）反应和临床结局的临床分化亚型 Molecular heterogeneity in non-muscle invasive bladder cancer reveals clinically divergent subtypes with contrasting Bacillus Calmette-Guérin response and clinical outcomes Jee-Woo Seo, Il-San Jeong, Yeo-Gyeong Yoon, Jae-Yoon Kim, Seon-Young Kim, Seung-Woo Baek, Seon-Kyu Kim
- 3874 3874 通过对新鲜冷冻内镜活检标本进行全面磷酸化蛋白质组学实现结直肠癌的磷酸化蛋白质组分型与表征 Phosphoproteomic subtyping and characterization of colorectal cancer by comprehensive phosphoproteomics of fresh frozen endoscopic biopsy specimens Jun Adachi, Hirokazu Shoji, Hidekazu Hirano, Yosui Nojima, Satoshi Muraoka, Yutaka Saito, Ken Kato, Narikazu Boku, Yukihide Kanemitsu
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- 3876 3876 Clearseq1-4肿瘤微环境分类在局限性和转移性透明细胞肾细胞癌中的预后与预测价值 Prognostic and predictive value of the Clearseq1-4 tumor microenvironment classification in localized and metastatic clear-cell renal cell carcinoma Benoit Beuselinck, Lisa Kinget, Edward Mctaggart, Octavie Demeulenaere, Edouard Roussel, Bram Boeckx, Jessica Zucman-Rossi, Gabrielle Couchy, Henri Vandermeulen, Liesbeth De Wever, Marcella Baldewijns, Agnieszka Wozniak, Diether Lambrechts, Stefan Naulaerts, Abhishek D. Garg, Annelies Verbiest, Maarten Albersen
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- 3878 3878 NEUROD1阳性及合并YAP1主导型肺神经内分泌癌中ZEB1的表达与局部免疫抑制微环境相关 ZEB1 expression in NEUROD1-positive and combined YAP1-dominant pulmonary neuroendocrine carcinomas is associated with a locally immunosuppressive microenvironment Noriko Takemura-Kobayashi, Kei Asayama, Rawya Mohamed Salih Ibrahim, Masahiro Maki, Ryota Matsuoka, Aya Shiba-Ishii, Ayako Suzuki, Yutaka Suzuki, Daisuke Matsubara
- 3879 3879 SPP1驱动的胶质母细胞瘤肿瘤相关中性粒细胞免疫代谢重编程 SPP1-driven immunometabolic reprogramming of tumor-associated neutrophils in glioblastoma Matthew Alexander Abikenari, John Hyunkuk Choi, Ravi Medikonda, Lily Kim, Rohit Verma, Justin Liu, Adam Sjoholm, George Nageeb, Brandon Hwa-Lin Bergsneider, Caren Yu-Ju Wu, Kwang Bog Cho, Andrew Tran, David Bakalov, Matei Banu, Michael Lim
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- 3883 3883 使用皮秒红外激光质谱统一平台在10秒内对中枢神经系统癌症进行形态计量学与分子学整合分类 Integrated morphometric and molecular classification of central nervous system cancers in 10 seconds using a unified platform with picosecond infrared laser mass spectrometry Alexa Nina Fiorante, Michael Woolman, David Munoz, Farshad Nassiri, Gelareh Zadeh, Sunit Das, Howard Ginsberg, Arash Zarrine-Afsar
- 3884 3884 基于多重免疫荧光的bintrafusp alfa治疗HER2阳性乳腺癌患者的空间分析：一项转化病理学研究 Multiplex immunofluorescence based spatial analysis of HER2 positive breast cancer patients treated with bintrafusp alfa: A translational pathology study Maria Gabriela Raso, Elizve N. Barrientos-Toro, June Li, Renganayaki K. Pandurengan, Harsh Batra, Ximing Tang, Diego Oliva Rico, Julia Mendoza Perez, Jill Schwartz Gomez, Senthil Damodaran, Alastair Thompson, Andreas W. Machl, Natalia Jacob, Jennifer Keating Litton, Rashmi Krishna Murthy, Cara L. Haymaker
- 3885 3885 将转录组膀胱癌亚型应用于国际队列中的上尿路尿路上皮癌（UTUC）揭示种族差异与转化局限性 Application of transcriptomic bladder-cancer subtypes to upper-tract urothelial carcinoma (UTUC) across international cohorts reveals racial differences and translational limitations Joshua M. Scurll, Henning Bahlburg, Tran Anh Thu (Wendy) Phung, John Heard, Mamoru Hashimoto, Kazutoshi Fujita, Daniel Luthringer, Toru Sakatani, Kaoru Murakami, Charles J. Rosser, Ewan A. Gibb, Peter C. Black, Hideki Furuya
- 3886 3886 使用标志性基因集特征的新型胶质母细胞瘤亚型分类：不良预后与TP53下游通路的关联 A novel glioblastoma subtype classification using hallmark gene set signatures: Association between poor prognosis and TP53 downstream pathway Yu Jin Kim, Jeongman Park, Woo Young Kwon, Jaejoon Lim, Sung Hwan Lee
- 3887 3887 采用共识基因组分期(Consensus Genomic Staging)对CoMMpass研究中的多发性骨髓瘤进行风险分层，可识别出高非洲遗传血统与低非洲遗传血统患者之间的差异 Multiple myeloma risk classification of CoMMpass using Consensus Genomic Staging identifies differences between patients with high and low African genetic ancestry Steven M. Foltz, Chaitanya R. Acharya, Alexander Gout, Yuxin Jin, David E. Avigan, Ravi Vij, Shaji Kunnathu Kumar, Sagar Lonial, Hearn Cho, Katie Wozniak, Jonathan J. Keats, Craig Cole, John D. Carpten, George J. Mulligan
- 3889 3889 早期肺类癌肿瘤的基因组-免疫表型图谱及其预后意义 Genomic-immunophenotypic landscape of early-stage pulmonary carcinoid tumors and their prognostic implications Song Xu, Lingling Zu, Ning Zhou, Jingya Wang, Xiongfei Li, Haixiang Yu, Sibo Peng, Chunxia Su, Dingzhi Huang
- 3890 3890 HDAC6作为多种癌症类型中汇聚的致癌与免疫调控枢纽 HDAC6 as a convergent oncogenic and immunoregulatory hub across multiple cancer types Chia-Wei Wu, Chia-Yi Hsu, Eing-Mei Tsai, Tsung-Hua Hsieh
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