PO.MCB06.03 · 分子与细胞生物学
Epigenetic Changes as Molecular Markers of Cancer
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- 3192 3192 全基因组 DNA 甲基化谱分析揭示雌激素受体阳性和阴性乳腺癌中不同的表观遗传图景及新型生物标志物 Genome-wide DNA methylation profiling reveals distinct epigenetic landscapes and novel biomarkers in estrogen receptor-positive and -negative breast cancers Dalma Müller, Balazs Gyorffy
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- 3200 3200 WREm6A Prism：食管鳞状细胞癌中m6A甲基化表达特征的单细胞测序及其临床转化 WREm6A Prism: Single-cell sequencing of m6A methylation expression signatures and its clinical translation in esophageal squamous cell carcinoma Yuan Li, Zhuya Xiao, Qian Mo, Qian Wang, Caiyutian Zhang, Tian Tang
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- 3204 3204 对不同族裔前列腺组织进行DNA甲基化分析以鉴定预测前列腺癌进展的新型生物标志物 DNA methylation profiling in ethnically diverse prostate tissues to identify novel biomarkers predicting prostate cancer progression Claire A. Stevens, Leonardo Gonzalez-Smith, Colton Stensrud, Divya Ranjith, Jenaye Mack, Sarah Buxbaum, Sara Falzarano, Suhn K. Rhie
- 3205 3205 早期乳腺癌的单细胞DNA甲基化揭示对驱动突变的表观基因组反应及进展与浸润的独特特征 Single cell DNA methylation of early breast cancer reveals epigenomic response to driver mutations and unique signatures of progression and invasion Ryan Mulqueen, Xiang Li, Mariam Mosaad, Shanshan Bai, Jianzhuo Li, Emi Sei, Savitri Krishnamurthy, Alastair Thompson, Nicholas E. Navin
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- 3209 3209 未甲基化游离 DNA 的酶促富集提高了片段组学分析对肺癌患者诊断的敏感性 Enzymatic enrichment of unmethylated cell-free DNA improves the sensitivity of fragmentomic analysis for the diagnosis of patients with lung cancer Valentina Miano, Paulina Siejka-Zielińska, Calum Mould, Sean Knight, Seamus Grundy, Robert K. Neely
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- 3212 3212 通过将 Interlace™ 全局甲基化发现与下一代测序检测 Labcorp Plasma Complete™ 相结合来增强循环肿瘤 DNA 的检测 Enhancing the detection of circulating tumor DNA by combining Interlace™ global methylation discovery with next-generation sequencing test Labcorp Plasma Complete™ Kimberly A. Holden, Cynthia Maddox, Calum Mould, Nana Mensah, Luca Tosti, Iwo Pieniak, Paulina Siejka-Zielinska, Stephen Evans, Debora Lucarelli, Robert Neely, Anthony Smith, Kenneth C. Valkenburg, Marcia Eisenberg, Brian Caveney, Eric Severson, Taylor J. Jensen, Shakti Ramkissoon, Jonathan Williams
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