Metabolism and Microbiome in Cancer Initiation and Prevention

• 3616 3616 BXQ-350 通过调节鞘脂代谢降低化疗诱导的周围神经病变的发生率、严重程度并延缓其发病时间 BXQ-350 reduces incidence, severity, and time to on-set of chemotherapy induced peripheral neuropathy via modulation of sphingolipid metabolism Gilles H. Tapolsky, Tariq Arshad, Michael Gazda, Nikhil Wilkins, Jackson Bond, James Beach
• 3617 · PDF 驱动头颈部癌前病变向浸润性病变进展的免疫基因组学改变 Immunogenomic alterations driving premalignant lesions to invasive lesions of the head and neck Foram Ujjvalkumar Vaidya, Alvaro Gutierrez, Abberly Lott Limbach, Bhavna Kumar, Martin P. Alphonse, James W. Rocco, Mariana Brait, Amanda Ewart Toland, David Sidransky
• 3618 · PDF 肥胖介导的细胞外囊泡分泌作为子宫内膜癌发生与进展的可靶向驱动因素 Obesity-mediated extracellular vesicle secretion as a targetable driver of endometrial cancer initiation and progression Lakshmi Narasimhan Chakrapani, Kalapana Deepa Priya Dorayappan, Ganesh Yadagiri, Shyam Sundaram, Gabriela S. Vendrell, Takahiko Sakaue, Jessica Velasquez, Xavier Ryon Washington Ramesh, Thangavel Muthusamy, Casey M. Cosgrove, David E. Cohn, David M. O'Malley, Selvendiran Karuppaiyah
• 3619 · PDF 红甘蓝汁重编程肠道微生物组并增强丁酸盐产生以预防结直肠癌 Red cabbage juice reprograms the gut microbiome and enhances butyrate production to prevent colorectal cancer Bineet Narayan, Yariswamy Manjunath, Nagabhhishek Sirpu Natesh, Chayanee Chanpanich, Parsa Ghadermazi, BLAKE ARCIGA, Samarth Kansara, Ajay Tosh, John Ulbrich, Mary Kate Grossmann, Hwang Jiwon, Van Nguyen, Vikas Satyananda, Jussuf T. Kaifi, Joshua Chan, Satyanarayana Rachagani
• 3620 3620 人类病毒组及其与晚期非小细胞肺癌患者免疫检查点抑制剂治疗临床获益的关联 The human virome and its association with clinical benefit of immune checkpoint inhibitor therapy among patients with advanced non-small cell lung cancer Anna E. Coghill, Jin Xu, Aleksandr Lazaryan, Doratha Armenthus Byrd, YOUNGCHUL KIM, Richard Pollenz, Lary A. Robinson
• 3621 · PDF 用于早期检测结直肠癌及癌前病变的粪便微生物组特征 Fecal microbiome signatures for early detection of colorectal cancer and precursor lesions Mariana Bisarro Dos Reis, Monise Tadin Reis, Ana Flávia Peres, Claudio Lyoiti Hashimoto, Denise Peixoto Guimarães, Jeremy Wang, Rui Manuel Reis
• 3622 3622 利用表达导向抗菌肽（gAMPs）的生物工程益生菌针对 CRC 相关具核梭杆菌的精准治疗 Precision therapy against CRC associated Fusobacterium nucleatum using bioengineered probiotics expressing guided antimicrobial peptides (gAMPs) Ankan Choudhury, Colin Scano, Allison Barton, Leigh Greathouse
• 3623 3623 抗肥胖药物替尔泊肽对肥胖相关激素依赖性乳腺癌小鼠模型中肿瘤微环境的影响 Effects of the anti-obesity medication tirzepatide on the tumor microenvironment in a mouse model of obesity-associated, hormone-dependent breast cancer. Charlotte E. Gibson, Amanda L. Kucinskas, Emma G. Bailey, Flora Tao, Katherine E. Sanchez, Katherine L. Cook, Erin D. Giles
• 3624 · PDF 长期跑步与结直肠腺瘤及癌症的风险 Long-term running and risk of colorectal adenoma and cancer Yiwen Zhang, Edward L. Giovannucci
• 3625 · PDF 绝经后女性的中心性和外周性肥胖与乳腺癌风险：11项队列研究的汇总分析 Central and peripheral adiposity and breast cancer risk in postmenopausal women: A pooled analysis of 11 cohort studies Isaias Leon-Cepeda, Craigg Pickett, Stephanie A. Smith-Warner, Robert J. MacInnis, Jeanine M. Genkinger
• 3626 · PDF 早年暴露与成年期癌症：世界癌症研究基金会国际组织的癌症生命历程研究 Early life exposures and cancer in adulthood: World Cancer Research Fund International's lifecourse research in cancer Vanessa Lani Zarya Gordon-Dseagu, Helen Croker, Panagiota Mitrou, Christelle Clary, John Krebs, Matty P. Weijenberg, Monica Baskin, Ellen Kampman, Laure Dossus, Fränzel J. Van Duijnhoven, Dieuwertje E. Kok, Moniek van Zutphen
• 3627 3627 未经治疗的早发性与晚发性结直肠癌患者中体力活动的代谢组学特征：ColoCare研究的结果 Metabolomic signatures of physical activity in treatment-naive patients with early-onset vs. late-onset colorectal cancer: Results from the ColoCare Study Victoria Maria Bandera, Tengda Lin, Patricia Erickson, Caroline Himbert, Aik Choon Tan, Mary C. Playdon, Alan Maschek, Paul Stewart, Sheetal Hardikar, Elaine M. Glenny, Jennifer Ose, Victoria Damerell, Christy A. Warby, Olena Aksonova, Oliver Fiehn, Kenneth Boucher, Peter Schirmacher, Ildiko Strehli, Megan Mclaws, Alejandro Sanchez, Jolanta Jedrzkiewicz, Lyen C. Huang, Vaia Florou, Jessica N. Cohan, Alexander Brobeil, Hans-Ulrich Kauczor, Christoph Kahlert, Meghana Karchi, Elizabeth H. Wood, Doratha A. Byrd, Erin M. Siegel, Adetunji T. Toriola, David Shibata, Christopher I. Li, Jane C. Figueiredo, Biljana Gigic, Jatin Roper, Stephen Hursting, Cornelia M. Ulrich
• 3628 · PDF 肥胖、代谢功能障碍与癌症风险：揭示代谢全景 Obesity, metabolic dysfunction, and cancer risk: Uncovering the metabolic landscape Liza Makowski, Mary Playdon, Bing Li, Sonia L. Sugg, Scott A. Summers, Cornelia M. Ulrich, Deirdre Tobias, Edward L. Giovannucci, Xuehong Zhang, James R. Hébert, E. Angela Murphy, Joeseph F. Pierre, Loretta DiPietro, Lorne J. Hofseth, Marinella Temprosa
• 3629 · PDF 路易斯安那队列中肥胖、糖尿病与前列腺癌侵袭性之间的关联 The association between obesity, diabetes and prostate cancer aggressiveness in Louisiana Cohort. Hari K. Koul, Denise danos, Yong yi, Augusto Ochoa, Lucio Miele, Xio-Cheng Wu
• 3630 · PDF 体力活动、吸烟与乳腺癌风险：英国生物银行的前瞻性队列研究 Physical activity, smoking and breast cancer risk: A prospective cohort study in the UK biobank Hannach Harsanyi, Andrew Harper, Heinz Freisling, Sasha Lupichuk, Adetunji T. Toriola, Lin Yang
• 3631 3631 早期BMI升高作为晚期NSCLC中免疫检查点抑制剂±化疗疗效的预测性生物标志物：整合临床、基因组和循环蛋白质组数据 Early BMI increase as a predictive biomarker for immune checkpoint inhibitor ±chemotherapy efficacyin advanced NSCLC: Integrating clinical, genomic, and circulating proteomic data Xinan Wang, Federica Pecci, Valentina Santo, Eleonora Gariazzo, Edoardo Garbo, Alessandro Di Federico, Joao Alessi, Yi Li, Biagio Ricciuti, David C. Christiani
• 3632 · PDF 肥胖与癌症：纳入迄今最大证据基础的最新荟萃分析 Adiposity and cancer: Updated meta-analysis incorporating the largest evidence base to date Eleanor Watts, Amparo Gonzalez-Feliciano, Marc Gunter, Nilanjan Chatterjee, Steven Moore
• 3633 · PDF HIV与HPV共感染在波多黎各HIV感染者口腔真菌组失调中的协同效应 Synergistic effects of HIV and HPV coinfection in dysregulation of the oral mycobiome in Puerto Rican people with HIV Juliana M. Serrano-Rodríguez, Jurelis Torres-Reyes, Yakshi N. Ortiz-Maldonado, Gabriel Borges-Vélez, Jeannette L. Salgado Montilla, María M. Sánchez-Vázquez, Magaly Martínez-Ferrer, Ramón F. González-García, Josué Pérez-Santiago
• 3634 · PDF 橄榄油副产品多酚富集提取物对肌肉功能、肌少症相关参数及皮肤健康的影响 Effects of olive oil byproducts polyphenol reach extract on muscle function, sarcopenia-related parameters and skin health Adriana Albini, Sara Nofri, Danilo Morelli, Paola Corradino, Gianni Lo Franco, Calogero Caruso, Anna Aiello
• 3635 3635 BEFIT运动干预初步研究的中期结果：评估肺癌高危队列的微生物组和免疫功能 Interim results of the BEFIT exercise intervention pilot study to assess the microbiome and immune function in a high-risk cohort for lung cancer Marisa Bittoni, Zachary Chaplow, Daniel Spakowicz
• 3636 3636 评估一项临床整合的移动健康干预以减少维持治疗期间ALL青少年和年轻成人久坐时间 Evaluation of a clinically integrated mHealth intervention to reduce sedentary time in adolescents and young adults with ALL during maintenance therapy Brittany J. Ivory, Yueh-Yun Chi, Jeannie M. Shin, Britni R. Belcher, David R. Freyer
• 3637 3637 通过靶向腺苷信号传导提高肥胖乳腺癌的治疗疗效 Improving therapeutic efficacy by targeting adenosine signaling in obese breast cancers Yueming Zhu, Amad Uddin, Xin Cui, Yong Wan

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