PO.CL08.02 · 临床研究
Effects of Ionizing Radiation on Normal Tissues and FLASH Radiation Research
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5264 · PDF An in vivo -validated dual-mechanism model explains and guides FLASH radiotherapy for normal-tissue sparing Lixiang Guo, Anthony Davis, Albert van der Kogel, Ken KangHsin Wang
- 5265 5265 FLASH radiotherapy improves survival in mouse glioblastoma and spares circulating antigen reactive CD8 + T-cells Yanxia Ma, Nhat Nguyen, Xuehong Gui, Edgardo Aguilar, Luke Connell, Denae Neill, Emil Schüler, Chibawanye I. Ene
- 5266 5266 FLASH radiotherapy maintains tumor control and enables safe re-irradiation while preserving normal tissue in breast cancer PDX models Adel Zaid I Mutahar, Banita Verma, Stavros Melemenidis, Suparna Dutt, Kerriann M. Casey, Zhen Qi, Angera Hsiao-Chi Kuo, Kathleen C. Horst, Edward Elliot Graves, Michael F. Clarke, Billy W. Loo, Frederick M. Dirbas
- 5267 5267 Reprogramming of pyruvate metabolism overcomes sex-specific differences in intestinal stem cell radiosensitivity and improves the therapeutic ratio for abdominal irradiation Stacey Krepel, Payel Bhanja, Rishi Man Chugh, Shujah Hamid Rehman, Subhrajit Saha
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5268 · PDF Genetic inhibition of FTO does not exacerbate the severity of radiation-induced oral mucositis in C57BL/6 mice Margaret Pan, Leighton Pu, Stavros Melemenidis, Edward Elliot Graves, Kerriann M. Casey, Erinn Rankin
- 5269 5269 Low-dose radiation therapy for peripheral joint osteoarthritis: Early U.S. community experience with pain, function, and medication outcomes Emily Schwartz, Michael Anderson, Russell Nevins, Kelsey Moakler, Andrew Cohen, Michael Sinopoli, Samuel Francis, Bradley Newby, Matthew Schwartz
- 5270 5270 Cell-free RNA changes precede symptomatic radiation pneumonitis in cancer patients receiving thoracic radiotherapy Isabel Jabara, Noah Kastelowitz, Monica Nesselbush, Nick Phillips, Michael S. Binkley, Rene F. Bonilla, Kevin Liu, Alice Jiang, Nataliya Kovalchuk, Ash A. Alizadeh, Maximilian Diehn
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5271 · PDF Pain signaling in dogs undergoing radiotherapy for head and neck cancer Faihaa A. Ahmed, Thitsana Ingkasri, Sophi Schofield, Effie Palyvou, Santosh K. Mishra, B. Duncan x Lascelles, Michael M. Nolan
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5273 · PDF Signaling pathway insights into spaceflight cancer risks Anu R I, Josef Borg, JangKeun Kim, Tricia Larose, Ryan T. Scott, Joseph Borg, Christopher E. Mason, Afshin Beheshti, Kurt van der Speeten
- 5274 5274 Impact of ultra-high dose rate (FLASH) versus conventional radiotherapy on tumor control in wild-type and cGAS-knockout mice Banita Verma, Adel Mutahar, Stavros Melemenidis, Rohit Verma, Lucy Whitemore, Suparna Dutt, Kathleen C. Horst, Edward Elliot Graves, Michael F. Clarke, Lingyin Li, Billy W. Loo, Frederick M. Dirbas
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5275 · PDF Mechanistic insights into the anti-tumor activity of ²¹²Pb-PSMA radioligand therapy Feifei Liu, Melissa Monterosso, Didier Boucher, Anna Amiss, Stelle Shakti, Kwong Ching Li, Chanwoo Kim, Aimee Horsfall, Kevin Kuan, William Tieu, Stephen Rose, Simon Puttick, Joana Brilhante, Gary Li, Anna Karmann, Thomas Kryza
- 5276 5276 [ 123 I]CC1, a radiopharmaceutical for Targeted radionuclide therapy (TRT), exploits PARP binding and trapping to amplify DNA damage and cytotoxicity in human cancer cell lines. Luis Hernandez Cano, Nerea Delgado Mayenco, Hilleen Kramer, Elmar Diekstra, Francesca Amoroso, Sreelakshmi Unnikrishnan, George Alachouzos, Wiktor Szymanski, Frank A. Kruyt, Bart Cornelissen
- 5277 5277 Alpha- and beta-emitter radiopharmaceutical therapy combined with dual immune checkpoint inhibitors yields distinct control of primary and metastatic tumors Yujuan Wang, Alexander Wertheim Verona, Bhoomika Raj Pillai, Tracy Berg, Caroline Kerr, Jamey P. Weichert, Reinier Hernandez, Bryan P. Bednarz, Zachary S. Morris