PO.ET02.07 · 实验与分子治疗
Innovative Therapeutic Modalities and Translational Platforms
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- 292 292 AOH1996，一种癌症相关 PCNA 抑制剂，恢复尿路上皮癌的铂类敏感性：体外和体内研究 AOH1996, a cancer-associated PCNA inhibitor, restores platinum sensitivity in urothelial carcinoma: In vitro and in vivo study Kuan-Lin Kuo, Kuo-How Huang, Yi Ju (Ellen) Kao, Chen-Hsun Hsu
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- 297 297 Cymirafen:一种按每周方案递送极高强度短脉冲MMAE的蛋白-药物偶联物 Cymirafen: A protein-drug conjugate that delivers very intense short pulses of MMAE on a weekly schedule Maria Carmen Mulero Roig, Sukshala A. Jadhav, Willie Pi, Stephen B. Howell
- 298 298 一种携带VEXAS综合征中常见UBA1突变的工程化人髓系细胞系对蛋白酶体抑制剂硼替佐米敏感 An engineered human myeloid cell line with a UBA1 mutation frequently detected in VEXAS syndrome is sensitive to the proteasome inhibitor bortezomib Hina Yazawa, Youhei Sasaki, Norihiko Kawamata
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- 302 302 评价胆固醇含量对纳米脂质体制剂抗葡萄膜黑色素瘤细胞摄取和制剂活性的影响 Evaluating the influence of cholesterol content on the cellular uptake and formulation activity of nanoliposomal formulations against uveal melanoma Shrey Mehulkumar Patel, Francielle Mourisso, Bilal Habibeh, Anna Kleckerova, Robert B. Campbell
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- 304 304 一项瘤内注射超高浓度一氧化氮(UNO)气体治疗皮肤及皮下实体瘤转移灶的1期研究 A phase 1 study of intratumoral ultra-high concentration nitric oxide (UNO) gas injection in cutaneous and subcutaneous solid tumor metastases Amichay Meirovitz, Steve Lisi, Kim Sheva, David Greenberg, John Jett
- 305 305 电化学疗法治疗非黑色素瘤皮肤癌：临床结局与耐受性 Non-melanoma skin cancer treated with electrochemotherapy: Clinical outcomes and tolerability Felipe Horacio Maglietti, Raquel Lertora, Nazarena S. Martinez, Alexandre Da Rosa Silva, Marina Ribeiro Damasceno Silva, Sebastian D. Michinski
- 306 306 整合计算与功能基因组学方法揭示UBE2Z-UBR2-E-钙黏蛋白轴是结直肠癌中β-catenin特异性的脆弱靶点 Integrative computational and functional genomic approach reveals UBE2Z-UBR2-Ecadherinaxis as a beta-catenin-specific vulnerability in colorectal cancer Chunhua Wan, Hugh Gao, Claire Sun, Ron Firestein
- 307 307 CCN5通过Merlin/NF2和Orai-1分子特征介导三阴性乳腺癌生长和转移的抑制 Triple-negative breast cancer growth and metastasis suppression by CCN5 is mediated by Merlin/NF2 and Orai-1 molecular signatures Inamul Haque, Gargi Maity, Jamie L. Porter, Snigdha Banerjee, Sushanta K. Banerjee
- 308 308 褪黑素在子宫平滑肌瘤和平滑肌肉瘤细胞系中的活性：一项关于其对间叶源性肿瘤抑制潜力的初步研究 Melatonin activity in uterine leiomyoma and leiomyosarcoma cell lines: A preliminary study of its inhibitory potential in mesenchymal tumors Tatielly T. Miranda, Edmund C. Baracat, Roseli S. Soares, Katia C. Carvalho
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- 310 310 NEU-002的转化开发：工程化治疗性弹性蛋白酶通过腹腔内和静脉给药展现出全身性抗肿瘤活性 Translational development of NEU-002: Engineered therapeutic elastases demonstrate systemic anti-tumor activity via intraperitoneal and intravenous administration Maria Fumagalli, Chang Cui, Ravindra Gujar, Nicole Martinez, Peter Haberz, Court Turner, Lev Becker
- 311 311 生产功能性重组蛋白以推进自身免疫性疾病治疗的整合策略 Integrated strategies for producing functional recombinant proteins to advance autoimmune disease therapeutics Wenlin Ren, Siwen Wang, An Ouyang, Spencer Chiang, Yu Sun
- 312 312 基于L.paracasei NPB01与L.rhamnosus GG序贯发酵的后生元对乳腺癌发挥抗肿瘤活性 Postbiotic based on sequential fermentation of L.paracasei NPB01 and L.rhamnosus GG exerts antitumor activities against breast cancer Roberto Berni Canani, Chiara Luongo, Laura Pisapia, Franca Oglio, Roberta Di Santillo, Alessia Gaeta, Chiara Scocco, Marco Michelini, Vittoria Mauriello, Alessia Cadavere, Camilla Messuri, Saranya Chumsri, Dawn Mussallem
