PO.MCB08.04 · 分子与细胞生物学
Genetic and Transcriptomic Dissection of Cancer Evolution
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- 5917 5917 慢性髓系白血病中NK细胞的单细胞图谱鉴定出具有不同基因调控特征、与伊马替尼停药后不同结局相关的独特细胞状态 Single-cell profiling of NK cells in chronic myeloid leukemia identifies distinct cell states with gene regulatory signatures associated with differential outcomes after imatinib discontinuation Santoshi Borra, Da Yan, Robert S. Welner, Zongliang Yue
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- 5925 5925 弥漫性胶质瘤中WHO 2021标准、WGS与DNA甲基化分类的诊断一致性：一项单中心队列研究 Diagnostic concordance of WHO 2021 standards, WGS, and DNA methylation classification in diffuse gliomas: A single-center cohort study Jungyu Kim, Yongjae Lee, Jeong Seok Lee, Tae Hoon Roh, YOUNG SEOK JU
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- 5932 5932 基于游离DNA的基因组分析揭示血管内大B细胞淋巴瘤独特的全基因组图景与时序 Cell free DNA based genomic analysis revealed the distinct whole genome landscape and chronology of intravascular large B cell lymphoma Takuto Mori, Kazuyuki Shimada, Kaito Mimura, Suguru Fukuhara, Koji Izutsu, Daisuke Kawauchi, Yoshitaka Narita, Akiko Miyagi Maeshima, Ryosuke Koyamada, Nobuhiro Hiramoto, Hirona Maeda, Nobuyuki Kakiuchi, Ai Okada, Kenichi Chiba, Yuichi Shiraishi, Akifumi Takaori−Kondo, Seishi Ogawa, Akihiro Tomita, Kenichi Yoshida
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- 5934 5934 来自单倍型特异性拷贝数改变泛癌图谱的染色体不稳定性基因组特征 Genomic signatures of chromosomal instability from a pan-cancer landscape of haplotype-specific copy-number alterations Chunyang Bao, Matthew Leventhal, Hansol Park, Gang-Hee Lee, Ryul Kim, Won-Chul Lee, Jonghoon Lee, Yoonsuh Lee, Beomki Lee, David Lehotzky, Ron Solan, Antonia Kowalewski, Xavi Loinaz, Vasuki Narasimha Swamy, David I. Heiman, Samantha Van Seters, Saveliy Belkin, Sam Wiseman, Andrew D. Cherniack, Luis Antonio Corchete Sanchez, Brian P. Danysh, Zachary Everton, Chip Stewart, Haruna Tomono, Gengchao Wang, Esther Rheinbay, Gad Getz, Cheng-Zhong Zhang, Young Seok Ju
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- 5939 5939 一项大规模测序研究鉴定出一个新的非编码结构变异作为黑色素瘤的高外显率易感变异 A large-scale sequencing study identifies a novel non-coding structural variant as a high-penetrance susceptibility variant for melanoma Linh T. Bui-Raborn, Lorenza Pastorino, Donato Calista, Huu Phuc Hoang, Bruna Dalmasso, Jessica Scales, Sophie Papiernik, Xiaoyu Wang, Rohit Thakur, Stefania Pellegrini, Mai Xu, Joshuah Yon, William Bruno, Tongwu Zhang, Zaida García-Casado, Enrica Teresa Tanda, Francesco Spagnolo, Monia Di Prete, Irene Bottillo, Siranoush Manukian, Maria Chiara Scaini, Katerina P. Kypreou, Lucia Di Nardo, Miriam Potrony, Paula Aguilera-Peiró, Nesreen Shahrour, Tam-Anh Tran, Weiyin Zhou, Wen Lou, Aurélie L. Vogt, Jia Liu, Kristine Jones, Monica Rodolfo, Irene Stefanaki, Cristina Pellegrini, Carlo Cota, Chiara Menin, Maria Concetta Fargnoli, Ketty Peris, Susana Puig, Eduardo Nagore, Paola Grammatico, The Melanostrum Consortium, Jianxin Shi, Paola Ghiorzo, Kevin M. Brown, Maria Teresa Landi
- 5940 5940 利用多组学数据进行染色体水平分相以解析多发性骨髓瘤的单倍型，揭示染色体间影响表观遗传状态和基因表达的复杂远端相互作用 Chromosome-level phasing to resolve haplotypes using multiomic data in multiple myeloma reveals complex distal interactions between chromosomes that impacts epigenetic states and gene expression Nathan J. Becker, Enze Liu, J. Zachary Sanborn, Attaya Suvannasankha, Kelvin Lee, Dickran Kazandjian, Benjamin Diamond, Abhishek Pandey, Rafat Abonour, Ola Landgren, Elizabeth M. Munding, Aneta Mikulasova, Brian A. Walker
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