PO.PR01.03 · 预防研究
Genomics, Proteomics, Biomarkers, and Risk Stratification
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6315 · PDF 活检证实的MASH患者中克隆性造血的高患病率及其对癌症诊疗的意义 High prevalence of clonal hematopoiesis in biopsy-proven MASH and implications for cancer care Sourat Darabi, Brian T. Lee, Tse-Ling Fong, Benjamin H. Goldenson, Carlos E. Zuazo, John S. Cupp, Michael J. Demeure, Patrick Lee, David R. Braxton
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6316 · PDF 持续性高级别癌前病变中p21+细胞的积聚及生长停滞特征的富集 Accumulation of p21+ cells and enrichment of growth arrest signature in persistent high-grade premalignant lesions Alexis Assante, Khosbayar Lkhagvadorj, Hyunmin Kim, Kimberly R. Jordan, Daniel T. Merrick, Robert L. Keith, York E. Miller, Moumita Ghosh
- 6317 6317 用于癌症甲基化生物标志物绝对定量的无参照PCR检测方法 A reference-free PCR assay for absolute quantification of cancer methylation biomarkers Ziming Li, Huichuan Yu
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6318 · PDF 致密乳腺组织中作为乳腺癌发生潜在驱动因素的独特分子特征 Distinct molecular signatures in dense breast tissue as potential drivers of breast cancer development Jay William Fox, Natalia Dworak, Patcharin Pramoonjago, Christopher A. Moskaluk, Ana Karina de Oliveira
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6319 · PDF 利用配对种系基因组预测儿童癌症的发病年龄 Using paired germline genome to predict the age of onset in pediatric cancer Kai Ren Chen, Safa Majeed Grant, Brianne Laverty, Ashby Kissoondoyal, Adam Shlien, David Malkin
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6320 · PDF 慢性肾脏病患者癌症风险的血浆蛋白质组学研究 Plasma proteomics of cancer risk in patients with chronic kidney disease Lucas A. Mavromatis, Aditya Surapaneni, Carina Flaherty, Peter Ganz, Lawrence J. Appel, Morgan E. Grams
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6321 · PDF 绝经后乳腺癌一种新的潜在危险因素——血浆蛋白LEG1同源物的特征刻画 Characterizing plasma protein LEG1 homolog, a novel potential risk factor for post-menopausal breast cancer Vernon A. Burk, Elizabeth A. Platz
- 6322 6322 揭示前列腺组织中与前列腺癌相关的因果蛋白标志物:一项全蛋白质组关联研究及功能验证 Uncovering causal protein markers in prostate tissue for prostate cancer: A proteome-wide association study and functional validation Jingjing Zhu, Pramod KC, Sweaty Koul, Yijun Tian, Hua Zhong, Thomas G. Beach, Hyeyoon Kim, Athena A. Schepmoes, Karl K. Weitz, Tyler Sagendorf, Tao Liu, Maarit I. Tiirikainen, Lucio Miele, Nicholas Mancuso, Timothy R. Rebbeck, David V. Conti, Christopher A. Haiman, the PRACTICAL/ELLIPSE consortium, Chong Wu, Liang Wang, Hari K. Koul, Lang Wu
- 6323 6323 血浆蛋白质组学分析揭示英国生物样本库中MASLD相关肝细胞癌与消化道肿瘤的共有生物标志物 Plasma proteomic profiling reveals shared biomarkers for MASLD-related hepatocellular carcinoma and gastrointestinal cancers in the UK Biobank Qing Wang, Yacong Zhang, Ke-Xin Chen
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6324 · PDF 基于蛋白质组学的模型提高上消化道肿瘤预测的准确性 A proteomics-based model improves the accuracy of upper gastrointestinal cancer prediction Xinyu Liu, Zhangyan Lyu, Kexin Chen
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6325 · PDF 肺癌的吸烟与性别特异性蛋白质组学标志物:一项前瞻性队列研究 Smoking and sex specific proteomic markers of lung cancer: A prospective cohort study Zhangyan Lyu, Xinyu Liu, Kexin Chen
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6326 · PDF 妊娠、哺乳及退化诱导健康女性乳腺组织的重塑和细胞状态变化 Pregnancy, lactation, and involution-induced remodeling and cell state changes in breast tissues of healthy women Poornima Bhat-Nakshatri, Cihat Erdogan, Hongyu Gao, Yunlong Liu, Rana German, Michele L. Cote, Harikrishna Nakshatri
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6327 · PDF 肺癌生物标志物从基于纳米颗粒的LCMS向酶联免疫吸附试验的转化 Translation of lung cancer biomarkers from nanoparticle-based LCMS to enzyme-linked immunosorbent assay Nga Ho, Jinlyung Choi, Guanhua Shu, Alicia Furlan, Ghristine Bundalian, Arcel Cunanan, Janelle Dela Vega, Jacob Waiss, Zachary Yanagihara, Joon-Yong Lee, Robert Zawada, Chinmay Belthangady, Brian Koh, Manway M. Liu, Bruce Wilcox
- 6328 6328 缺氧诱导因子1-α在不同组织学类型子宫颈癌中的表达及其与肿瘤类型侵袭性的相关性:一项免疫组化研究 Expression of hypoxia-inducible factor 1-alpha in diverse histological types of uterine cervical carcinoma and correlation with the aggressiveness of tumor type: An immunohistochemical study Conwell Ngobeni, Meshack Bida, Benny Mosoane, Rahaba Marima, Tebogo Marutha, Zodwa Dlamini, Tebogo Medupe
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6329 · PDF 通过处理器介导的PCR提高高危型HPV基因型检测的灵敏度 Improved sensitivity in high-risk HPV genotype detection via processor-mediated PCR Niloufar Mertz, Eric K. Pomaranski, Adam McCoy, Vladimir Makarov
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6330 · PDF 评估亚洲卵巢癌女性中靶向BRCA检测与普遍BRCA检测的比较 Evaluating targeted versus universal BRCA testing in Asian women with ovarian cancer Boon Hong Ang, Sook-Yee Yoon, Joanna Lim, Nur Tiara Hassan, Mei-Chee Tai, Zhi Lei Wong, Jo Yi Chow, Xin Wen Lee, Meow-Keong Thong, Gaik‑Siew Ch’ng, Jamil Omar, Chee‑Meng Yong, Ismail Aliyas, Rozita Abdul Malik, Suguna Subramaniam, Wee‑Wee Sim, Chun-Sen Lim, Saw-Joo Lee, Keng‑Joo Lim, Mohamad Nasir Shafiee, Fuad Ismail, Mohd Pazudin Ismail, Mohamad Faiz Mohamed Jamli, Suresh Kumarasamy, John Seng Hooi Low, Ahmad Muzamir Ahmad Mustafa, Mary Jenifer Makanjang, Shahila Tayib, Nellie Lay Chin Cheah, Chee‑Kin Fong, Kean‑Fatt Ho, Azura Deniel, Soo-Fan Ang, Ahmad Radzi Ahmad Badruddin, Lye-Mun Tho, Boon‑Kiong Lim, Yin Ling Woo, Weang-Kee Ho, Soo-Hwang Teo
- 6331 6331 面向结直肠息肉诊断检测开发的高多重空间图谱分析与复杂度降低转化框架 A translational framework for high-plex spatial profiling and complexity reduction toward diagnostic assay development in colorectal polyps Ettai Markovits, Joanne Edwards, Gerard Patrick Lynch, Ofir Rimer-Cohen, Aidan Lynch, Aula Ammar, Luke McNickle, Claire Kennedy-Dietrich, Amna Matly, Meir Azulay, Lina Sakhneny, Noori Maka, Lewis Irvine, Pamela McCall, Ken Bloom, Grainger Greene, Stephen McSorley, Nigel Jamieson
- 6332 6332 应用于RADIOHEAD队列的nELISA高通量蛋白质图谱分析:来自接受检查点抑制剂治疗患者的最大规模血浆蛋白质组学研究的洞见 nELISA high-throughput protein profiling applied to the RADIOHEAD cohort: Insights from the largest plasma proteomics study of patients receiving checkpoint inhibitor therapy Amy R. Johnson, Nathaniel Robichaud, Samantha I. Liang, Jens Eberlein, Grant Ongo, Enjun Yang, John CONNOLLY, Milad Dagher
- 6333 6333 利用整合蛋白质组学与多变量模式分析识别初治非裔美国女性乳腺癌特异性血清蛋白质特征 Serum protein signatures specific to breast cancer in treatment-naive African American women identified using integrated proteomics and multivariate pattern analysis Padma P. Tadi Uppala, Hyun J. Kwon, Elmer C. Rivera, Sharon S. Lum
- 6334 6334 CervicalMethDx:一种可实现居家采样、扩大宫颈癌预防可及性并减少美国和波多黎各不必要活检的精准工具 CervicalMethDx: A precision tool to enable at-home sampling and expand access to cervical cancer prevention while reducing unnecessary biopsies in the United States and Puerto Rico. Ashley Ramos Lopez, Yanira Gonzalez Rodriguez, Amanda Garcia Negron, Paola Quinonez Mendez, Guie Beeu Guerrero Hunt, Adhi Guerrero Thillet, Mariana Brait, Teresa Díaz-Montes, Josefina Romaguera, Lourdes Fernadez, David Sidransky, Rafael E. Guerrero-Preston
- 6335 6335 PC3前列腺癌细胞中EGF诱导转录级联反应的时序图谱揭示双相致癌重编程 Temporal profiling of the EGF-induced transcriptional cascade in PC3 prostate cancer cells reveals biphasic oncogenic reprogramming Amit Kumar Tripathi, Jamboor K. Vishwanatha
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6336 · PDF 环境温度下cfRNA的保存:标准化提取揭示多分析物采集管中更优的稳定性 AmbientcfRNApreservation: standardized extraction reveals superior stability in a multi-analyte tube Emily Medina, Tony Baker, Kamran Syed, Jason Saenz, Cameron Van Dieren, Carlos Hernandez, Daniel Cedeno, Mayer Saidian, Nafiseh Jafari
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6337 · PDF 通过处理器介导PCR实现单反应KRAS变异图谱分析:利用iProbe增强SNV区分能力 Single-reaction KRAS variant profiling via processor-mediated PCR: Enhanced SNV discrimination using the iProbe Eric K. Pomaranski, Adam M. McCoy, Karl Spork, Niloufar Mertz, Vladimir Makarov
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6338 · PDF 用于肾癌筛查和分层的多基因血液检测的临床验证 Clinical validation of a multi-gene blood test for kidney cancer screening and stratification Taigo Kato, Koji Hatano, Yohei Okuda, Dharam P. Chauhan, Norio Nonomura, Rajvir Dahiya
- 6339 6339 利用甲基化敏感性限制性内切酶消化和微滴数字PCR对一种新型供者来源参考物质进行甲基化谱分析 Methylation profiling of a novel donor-derived reference material using methylation-sensitive restriction enzyme digestion and droplet digital PCR Daniel Wasik, Yves Konigshofer, Mona Shahbazian, Adam Corner, Eddy vanCollenburg, Jayanthi Ramprakash, Nish Kumar, Andrew Anfora, Mai Ho
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6340 · PDF 在HCC患者血清样本中检测异位磷酸化PDGFRA抗体 Detection of ectopic phosphorylated PDGFRA antibodies in the serum samples of HCC patients Jian-Hua Luo, Muhamuda Kader, Yan-Ping Yu
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6341 · PDF 利用人工智能从组织病理学图像中高保真地检测和分类卵巢癌 High-fidelity detection and classification of ovarian cancer from histopathological images using Artificial Intelligence Elangovan Krishnan, Jansi R. Sethuraj, Sophia Ahmed, Gowrishankar Palaniswamy, Muhammad Waqas Khan, Aravind Raghavan, Tayyiba Wasim
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6342 · PDF Li-Fraumeni综合征纵向癌症筛查的效能 Performance of longitudinal cancer screening in Li-Fraumeni syndrome Payal P. Khincha, Sophia Ty, Siddharth Roy, Jessica N. Hatton, Ashkan Malayeri, Megan N. Frone, Margarita Aryavand, Phuong Mai, Paul Albert, Sharon A. Savage
- 6343 6343 整合蛋白质组学、转录组学和基于FACS的表面标志物数据用于癌细胞系中ADC靶标的发现 Integrative analysis of proteomic, transcriptomic, and FACS-based surface marker data for ADC target discovery in cancer cell lines Nadine Obier, Vincent Vuaroqueqeaux, Johannes Krumm, Anne-Lise Peille, Daniel Feger, Sarah Ulrich, Johanna Wallner, Hannes Hahne, Jan E. Ehlert