PO.PR02.02 · 预防研究
Cancer and Cancer Related Alterations, Detection Approaches, and Molecular Characterization
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7614 · PDF 使用早期可用的Illumina protein prep 6K检测和机器学习进行癌症早期检测 Early cancer detection using early-access Illumina protein prep 6K assay and machine learning KAMEL LAHOUEL, Mete Mulazimoglu, Kameron Bates, Candice Wike, Kunjur Manasa Upadhyaya, Victoria Zismann, Kamawela Leka, Payton Smith, Gracyn Benck, Kianna Martos Rupp, Chaney Jambor, Matteo Munini, Sophie Pénisson, Stephanie Pond, Jeffrey Trent, Patrick Pirrotte, Cristian Tomasetti
- 7615 7615 采用基于PCR的单分子计数技术,在简化的单管流程中多重检测BCR-ABL1融合转录本 Multiplex detection of BCR-ABL1 fusion transcripts in a streamlined single-tube workflow using PCR-based single molecule counting Vladyslava Ratushna, Jung won Keum, Christina Fan
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7616 · PDF 采用多组学液体活检技术早期检测胰腺癌 Early detection of pancreatic cancer with a multi-omic liquid biopsy James M. Cameron, Holly J. Butler, David S. Palmer, Rose G. McHardy, Matthew J. Baker
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7617 · PDF 采用多组学液体活检技术更早期地检测卵巢癌 A multi-omic liquid biopsy for the earlier detection of ovarian cancer James M. Cameron, Holly Butler, David Palmer, Rose McHardy, Matthew Baker
- 7619 7619 PanGIA分析系统:一种通过口腔样本对口腔癌进行无创诊断的新型机器学习平台 PanGIA Analysis System, a novel machine learning platform for non-invasive diagnosis of oral cancer through an oral sample Francis Lim, Abhignyan Nagesetti, Nick Gonzalez, Miguel Javiel, Pablo Hernandez, Kyle Ambert, Robert Cardwell, Obdulio Piloto
- 7620 7620 PanGIA分析系统:一种通过尿液对多种癌症进行无创诊断的新型机器学习平台 PanGIA Analysis System, a novel machine learning platform for non-invasive diagnosis of multiple cancers through urine Abhignyan Nagesetti, Francis Lim, Nick Gonzalez, Miguel Javiel, Pablo Hernandez, Kyle Ambert, Robert Cardwell, Obdulio Piloto
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7621 · PDF 通过无创、无标记电化学免疫传感器探针检测早发性结直肠癌 Early-onset colorectal cancer detection through a non-invasive label-free electrochemical immunosensor probe Ruma Paul, Md Zahirul Islam Khan, Soumya Nair, Alicia I Loya, Sourav Roy, Carlos R. Cabrera
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7622 · PDF 突破可规模化多癌种早期检测(MCED)的障碍 Breaking barriers to scalable multi-cancer early detection (MCED) Bahram G. Kermani
- 7623 7623 利用红细胞DNA图谱分析无创检测早期结直肠肿瘤:一项前瞻性临床验证 Non-invasive detection of early colorectal neoplasia using red blood cell DNA profiling: a prospective clinical validation Chengcheng Liu, Xingyun Yao, Haobo Sun, Yurong Jiao, Xiangxing Kong, Jie Jin, Kefeng Ding, Jun Li, Xiaofei Gao
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7624 · PDF 由新型80万位点双峰扩增子测序技术实现的液体活检多癌种早期检测 Liquid biopsy MCED enabled by a novel 800K-locus bimodal amplicon sequencing technology Kamel Lahouel, Kameron Bates, Victoria Zismann, Candice Wike, Kunjur Manasa Upadhyaya, Matteo Munini, Mete Mulazimoglu, Gracyn Benck, Kianna Martos Rupp, Payton Smith, Chaney Jambor, Sophie Pénisson, Stephanie Pond, Jeffrey Trent, Cristian Tomasetti
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7625 · PDF 基于血液的肿瘤缺氧检测方法的开发 Development of a blood-based tumor hypoxia detection assay Azemat Jamshidi-Parsian, Ruud Petrus Dings, Rajshekar A. Kore, Narasimhan Rajaram, Varsha Karunakaran, Robert J. Griffin
- 7626 7626 一种预测导管原位癌进展为浸润性乳腺癌风险的基因表达分类器 A gene expression classifier to predict progression risk of ductal carcinoma in situ to invasive breast cancer William Joseph Harley, Maria Roman-Escorza, Jelle Wesseling, Elinor Sawyer, Renee X. de Menezes, Esther Lips
- 7627 7627 多组学整合揭示晚间昼夜节律偏好通过共享的神经-内分泌-免疫通路成为癌症-抑郁共病的因果风险因素 Multi-omics integration reveals evening circadian preference as a causal risk factor for cancer-depression comorbidity through shared neuro-endocrine-immune pathways Liansha Tang, Wenbo He, Handan Hu, Jiayao Wang, Jiyan Liu
- 7628 7628 使用荧光氮-空位中心纳米金刚石从人黑色素瘤细胞系和FFPE组织中灵敏检测microRNA Sensitive detection of microRNAs from human melanoma cell lines and FFPE tissue using fluorescent nitrogen-vacancy center nanodiamonds Isaac Rampersaud, Charles Fletcher, Colin Angell, William E. Carson, Arfaan Rampersaud
- 7630 7630 剪切波弹性成像与光声成像无创识别肿瘤微环境中的耐药区域 Shear wave elastography and photoacoustic imaging to non-invasively identify resistant regions in the tumor microenvironment Sarah K. Burris, Caroline O'Riordan, Peter Kesa, Philippe Trochet, Dieter Fuchs
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7631 · PDF 预测和预防近地轨道中的癌症干性 Predicting and preventing cancer stemness in low Earth orbit Jessica Pham, Wenxue Ma, Claire Engstrom, Patrick Chang, Shuvro P. Nandi, Inge van der Werf, Emma Klacking, Teresa Sposito, Kendale Wirtjes, Thomas Frias, Antonio Ruiz, Jane Isquith, Luisa Ladel, Christina N. Wu, Jana Stoudemire, Pinar Mesci, Kay T. Yeung, Rebecca A. Shatsky, Anna A. Khachatrian, James J. La Clair, Michael D. Burkart, Peggy Wentworth, Curtis L. Scribner, Sheldon R. Morris, Thomas Whisenant, Karla Mack, Ludmil B. Alexandrov, Catriona H. M. Jamieson
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7632 · PDF 血浆蛋白质组学用于肺癌风险预测 Plasma proteomics for risk prediction of lung cancer Tej Pandya, Maria Zagorulya, Michelle M. Leung, Marcellus Augustine, Lydia Y. Liu, Oleg Blyuss, Jincheng Wu, Marc Pelletier, Vernon Burk, Neil Wright, David Muller, Ka Hung Chan, Ekaterina Pazukhina, Marc Gunter, Elizabeth A. Platz, Karl Smith-Byrne, Nuno Rocha Nene, Eva Camilla Gronroos, Nicholas McGranahan, William Hill, Clare Weeden, Charles Swanton
- 7633 7633 动态监测并识别可预测bireociclib联合氟维司群疗效的可靠生物标志物:BRIGHT-2研究的探索性ctDNA分析 Dynamic monitoring and identification of reliable biomarkers to predict efficacy of bireociclib and fulvestrant: An exploratory ctDNA analysis of the BRIGHT-2 study Yan Wang, Hangcheng Xu, Yiran Zhou, Liang Cui, Qiang Sa, Hong Cheng, Renchi Gao, Qingyuan Zhang, HHiping Li, Zhongsheng Tong, Quchang Ouyang, Xinxin Tan, Jing Bai, Li Wang, Xianghui Duan, Fan Yang, Jiayu Wang, Binghe Xu
- 7635 7635 阐明RELT与Filamin A之间的分子相互作用及该相互作用在乳腺癌细胞中的生理学作用 Elucidating the molecular interaction between RELT and Filamin A and the physiological role of this interaction in breast cancer cells Samantha Wong, Ashley Ko, Yashar Pourmoghadam, Hunter Hudgins, Maryann Batiste, Bethany Joy, Ashley Christensen, Eslam Mohamed, John K. Cusick
- 7636 7636 一种罕见的多能钉状(peg-like)上皮细胞是高级别浆液性卵巢癌的候选起源细胞 A rare multipotent peg-like epithelial cell is a candidate cell-of-origin for high-grade serous ovarian cancer Megan L. Ritting, Wenmei Yang, Syed Mohammed Musheer Aalam, Hui Zhao, Liang Feng, Jianning Song, Mihai G. Dumbrava, Wazim M. Ismail, Kenneth Schaufelberger, S. John Weroha, Scott H. Kaufmann, Alexandre Gaspar-Maia, Mark E. Sherman, Jamie N. Bakkum-Gamez, Nagarajan Kannan
- 7637 7637 全基因组CRISPR筛选揭示了二甲双胍用于口腔癌预防的一种PKA驱动耐药机制,该机制可通过联合NSAIDs加以利用 Genome-wide CRISPR screening reveals a PKA-driven resistance mechanism to metformin for oral cancer prevention that can be exploited by combination with NSAIDs Thomas S. Hoang, Farhoud Faraji, Amaya Mendez-Molina, Sendi R. Adame-Garcia, Kuniaki Sato, Tomohiko Ishikawa, Pham Thuy Vo, Sydney Ramirez, Paola Y. Anguiano Quiroz, Tracy Guo, Katie Fan, Xingyu Wu, Alfredo Molinolo, Ezra E. W. Cohen, Prashant Mali, Scott M. Lippman, J. Silvio Gutkind
- 7639 7639 灵长类比较肿瘤学揭示人类独特的癌症易感性 Primate comparative oncology reveal humans' unique cancer susceptibility Zachary Taylor Compton, Walker Mellon, Lisa M. Abegglen, Tara Harrison, Joshua D. Schiffman, Amy M. Boddy, Carlo C. Maley
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7640 · PDF 纤毛细胞驱动输卵管上皮中关键的STING介导的肿瘤抑制 Ciliated cells drive critical STING-mediated tumor suppression in fallopian tube epithelium Jose Colina, Maria Sol Recouvreux, Alex Sobeck, Benjamin K. Johnson, Yinzhi Lin, Sreeja C. Sekhar, Rita A. Avelar, Gabriela Rivera, Yali Zhai, amber fatima, Paula DiBenedetto, Justin Baldassarre, Grace McIntyre, Jessica Teitel, Michele Cusato, Harini Ram, Noah Puleo, Karan Bedi, Jane Miglo, Hui Shen, Dafydd G. Thomas, Jutta Huvila, Dawn R. Cochrane, Ronny I. Drapkin, Yu Lei, Joanna E. Burdette, David G. Huntsman, Kathleen Cho, Sandra Orsulic, Analisa DiFeo
- 7641 7641 解码错配修复缺陷型结直肠癌发生中免疫微环境的空间构筑 Decoding the spatial architecture of the immune microenvironment in mismatch repair-deficient colorectal carcinogenesis Abel Martel-Martel, Nan Deng, Melissa W. Taggart, Araceli Garcia-Gonzalez, Jacklyn V. Thompson, Luigi Ricciardiello, Y. Nancy You, Selvi Thirumurthi, Krishna M. Sinha, Eduardo Vilar
- 7642 7642 尼古丁依赖部分介导了吸烟者中IP6K3遗传变异与肺鳞状细胞癌风险之间的关联 Nicotine dependence partially mediates the association between IP6K3 genetic variation and risk of lung squamous cell carcinoma among smokers Jing Jin, Yasir Rahmatallah, Horacio Gomez-Acevedo, Yong-Moon (Mark) Park, David Ussery, Mohammed Orloff
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7643 · PDF 一种新型pH敏感探针,用于在高通量/高内涵成像平台上定量检测自噬 A novel pH-sensitive probe to quantify autophagy on high throughput/content imaging platforms Giuseppe D. Ciccotosto, Lorenzo Lorenzo, David L. Hare, Peter J. Wookey