PO.TB04.01 · 肿瘤生物学
Ex Vivo Systems: Patient-Derived, Patient-Specific Tumor Cultures
- 653 653 对零代患者脑肿瘤组织进行快速药物敏感性检测以指导临床前和临床决策：一项临床可行性研究的结果 Rapid drug sensitivity testing of passage-zero patient brain tumor tissues to inform preclinical and clinical decisions: results from a clinical feasibility study Breanna Mann, Nichole Artz, Adebimpe Adefolaju, Alain Valdivia, Xiaopei Zhang, Rajaneekar Dasari, Caroline Stockwell, Morrent Thang, Allison Murray, Noah Bell, Andrew Buckley, Rami Darawsheh, Kerry Fitzgerald, Jonathan Williams, Hardik Parikh, Shuang Gao, Jie An, Yvette Rodriguez, Daniel Metzger, Collin Parrow, Dylan Riley, Robert Seager, Stephanie B. Hastings, Taylor Jensen, Shakti Ramkissoon, Dominique Higgins, Yasmeen Rauf, Scott Elton, Kimberly Hamilton, Jeremy Wang, Albert Baldwin, Shawn Hingtgen, David Kram, Andrew Satterlee
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- 659 659 使用Nilogen的3D-EXpress平台在卵巢肿瘤类球体中离体评估一种MUC1靶向双特异性T细胞衔接器 Ex vivo evaluation of a MUC1-targeted bispecific T-cell engager in ovarian tumoroids using Nilogen's 3D-EXpress platform Vanessa Garrido, Janine DeBlasi, Andrea Mockabee, Seth Currlin, Justin Silberman, Jessica Linkous, Alliyah Humphrey, Jared Ehrhart
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- 661 661 在一个维持零代次患者肿瘤组织及其天然免疫抑制微环境的离体平台中快速检测CAR T Rapid CAR T testing in an ex vivo platform that maintains passage-zero patient tumor tissues and their native immunosuppressive microenvironment Xiaopei Zhang, Breanna Mann, Adebimpe Adefolaju, Alain Valdivia, Rajaneekar Dasari, Caroline Stockwell, Noah Bell, Ashley Geiger, Tracy A. Withers, Xin Zhou, Alexa Rodriguez, Kerry Fitzgerald, Jon Williams, Hardik Parikh, Shuang Gao, Jie An, Taylor Jensen, Shakti Ramkissoon, Dominique Higgins, Yasmeen Rauf, Scott Elton, Kimberly Hamilton, Albert Baldwin, Barbara Savoldo, Shawn Hingtgen, David Kram, Andrew Satterlee
- 662 662 利用离体人体组织和活细胞生物传感器的非动物平台实现肾细胞癌的功能性药物检测 Non-animal platforms using ex-vivo human tissue and live-cell biosensors enable functional drug testing in renal cell carcinoma Shuchi Gulati, Madhura Patankar, Elijah Kofke, Michael Pargett, Daniel Oberbauer, Ching-Hsien Chen, John G. Albeck
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- 665 665 弥合肿瘤异质性与药物反应：用于转化肿瘤学的患者来源免疫活性3D球状体模型 Bridging tumor heterogeneity and drug response: A patient-derived immune-competent 3D spheroid model for translational oncology Charlotte Veser, Zuzanna Kotkowska, Irina Agarkova, Sue Grepper, Madhu Nag-LAL, Laure-Anne Ligeon
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- 668 668 建立患者来源类器官-免疫细胞共培养平台用于评估免疫肿瘤学疗法的疗效 Establishment of a patient-derived organoid-immune cell co-culture platform for evaluating the efficacy of immuno-oncology therapies Yuhui Wang, Pengyu Li, Chuyue Yu, Mingshuo Zhang, Pengwei Pan, Fang He
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- 672 672 绘制肿瘤异质性图谱：使用3D功能精准平台评估同期匹配的原发与转移肿瘤的离体药物反应 Mapping tumor heterogeneity: Ex-Vivo drug responses in synchronous matched primary and metastatic tumors using a 3D functional precision platform Rajeshwar Nitiyanandan, Ivan Trus, Chiara Maestri, Ricardo J. Parker, Chris Apfel
- 673 673 在抗PD1治疗的患者来源类器官型肿瘤球体（PDOTS）中对免疫激活与肿瘤反应进行纵向图谱绘制 Longitudinal mapping of immune activation to tumor response in anti-PD1-treated patient-derived organotypic tumor spheroids (PDOTS) Jun Yang, Julia Vail, Eunju Shin, Kyungjin Boo, Kirti Khardenavis, Sinal Patel, Kyoung Wan Yoon, Michael A. Perricone
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