PO.TB04.01 · 肿瘤生物学
Ex Vivo Systems: Patient-Derived, Patient-Specific Tumor Cultures
- 653 653 Rapid drug sensitivity testing of passage-zero patient brain tumor tissues to inform preclinical and clinical decisions: results from a clinical feasibility study Breanna Mann, Nichole Artz, Adebimpe Adefolaju, Alain Valdivia, Xiaopei Zhang, Rajaneekar Dasari, Caroline Stockwell, Morrent Thang, Allison Murray, Noah Bell, Andrew Buckley, Rami Darawsheh, Kerry Fitzgerald, Jonathan Williams, Hardik Parikh, Shuang Gao, Jie An, Yvette Rodriguez, Daniel Metzger, Collin Parrow, Dylan Riley, Robert Seager, Stephanie B. Hastings, Taylor Jensen, Shakti Ramkissoon, Dominique Higgins, Yasmeen Rauf, Scott Elton, Kimberly Hamilton, Jeremy Wang, Albert Baldwin, Shawn Hingtgen, David Kram, Andrew Satterlee
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- 659 659 Ex vivo evaluation of a MUC1-targeted bispecific T-cell engager in ovarian tumoroids using Nilogen's 3D-EXpress platform Vanessa Garrido, Janine DeBlasi, Andrea Mockabee, Seth Currlin, Justin Silberman, Jessica Linkous, Alliyah Humphrey, Jared Ehrhart
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- 661 661 Rapid CAR T testing in an ex vivo platform that maintains passage-zero patient tumor tissues and their native immunosuppressive microenvironment Xiaopei Zhang, Breanna Mann, Adebimpe Adefolaju, Alain Valdivia, Rajaneekar Dasari, Caroline Stockwell, Noah Bell, Ashley Geiger, Tracy A. Withers, Xin Zhou, Alexa Rodriguez, Kerry Fitzgerald, Jon Williams, Hardik Parikh, Shuang Gao, Jie An, Taylor Jensen, Shakti Ramkissoon, Dominique Higgins, Yasmeen Rauf, Scott Elton, Kimberly Hamilton, Albert Baldwin, Barbara Savoldo, Shawn Hingtgen, David Kram, Andrew Satterlee
- 662 662 Non-animal platforms using ex-vivo human tissue and live-cell biosensors enable functional drug testing in renal cell carcinoma Shuchi Gulati, Madhura Patankar, Elijah Kofke, Michael Pargett, Daniel Oberbauer, Ching-Hsien Chen, John G. Albeck
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- 665 665 Bridging tumor heterogeneity and drug response: A patient-derived immune-competent 3D spheroid model for translational oncology Charlotte Veser, Zuzanna Kotkowska, Irina Agarkova, Sue Grepper, Madhu Nag-LAL, Laure-Anne Ligeon
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- 668 668 Establishment of a patient-derived organoid-immune cell co-culture platform for evaluating the efficacy of immuno-oncology therapies Yuhui Wang, Pengyu Li, Chuyue Yu, Mingshuo Zhang, Pengwei Pan, Fang He
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- 672 672 Mapping tumor heterogeneity: Ex-Vivo drug responses in synchronous matched primary and metastatic tumors using a 3D functional precision platform Rajeshwar Nitiyanandan, Ivan Trus, Chiara Maestri, Ricardo J. Parker, Chris Apfel
- 673 673 Longitudinal mapping of immune activation to tumor response in anti-PD1-treated patient-derived organotypic tumor spheroids (PDOTS) Jun Yang, Julia Vail, Eunju Shin, Kyungjin Boo, Kirti Khardenavis, Sinal Patel, Kyoung Wan Yoon, Michael A. Perricone
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